| Full name: interferon alpha 2 | Alias Symbol: IFNA|IFN-alphaA | ||
| Type: protein-coding gene | Cytoband: 9p21.3 | ||
| Entrez ID: 3440 | HGNC ID: HGNC:5423 | Ensembl Gene: ENSG00000188379 | OMIM ID: 147562 |
| Drug and gene relationship at DGIdb | |||
IFNA2 involved pathways:
Expression of IFNA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFNA2 | 3440 | 211338_at | -0.0668 | 0.7576 | |
| GSE20347 | IFNA2 | 3440 | 211338_at | -0.0245 | 0.6602 | |
| GSE23400 | IFNA2 | 3440 | 211338_at | -0.0382 | 0.0943 | |
| GSE26886 | IFNA2 | 3440 | 211338_at | -0.1325 | 0.2003 | |
| GSE29001 | IFNA2 | 3440 | 211338_at | -0.0943 | 0.4595 | |
| GSE38129 | IFNA2 | 3440 | 211338_at | -0.0695 | 0.1102 | |
| GSE45670 | IFNA2 | 3440 | 211338_at | 0.0031 | 0.9742 | |
| GSE53622 | IFNA2 | 3440 | 44936 | -0.4971 | 0.0000 | |
| GSE53624 | IFNA2 | 3440 | 44936 | -0.3905 | 0.0001 | |
| GSE63941 | IFNA2 | 3440 | 211338_at | 0.1672 | 0.2689 | |
| GSE77861 | IFNA2 | 3440 | 211338_at | -0.1662 | 0.0894 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFNA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFNA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFNA2 | 3440 | 2 | 17 | 11 | |
| GSE20123 | IFNA2 | 3440 | 2 | 17 | 11 | |
| GSE43470 | IFNA2 | 3440 | 3 | 13 | 27 | |
| GSE46452 | IFNA2 | 3440 | 2 | 24 | 33 | |
| GSE47630 | IFNA2 | 3440 | 3 | 27 | 10 | |
| GSE54993 | IFNA2 | 3440 | 7 | 2 | 61 | |
| GSE54994 | IFNA2 | 3440 | 8 | 17 | 28 | |
| GSE60625 | IFNA2 | 3440 | 3 | 0 | 8 | |
| GSE74703 | IFNA2 | 3440 | 3 | 10 | 23 | |
| GSE74704 | IFNA2 | 3440 | 0 | 13 | 7 | |
| TCGA | IFNA2 | 3440 | 11 | 53 | 32 |
Total number of gains: 44; Total number of losses: 193; Total Number of normals: 251.
Somatic mutations of IFNA2:
Generating mutation plots.
Highly correlated genes for IFNA2:
Showing top 20/147 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFNA2 | KIR2DS4 | 0.650835 | 3 | 0 | 3 |
| IFNA2 | PRL | 0.635217 | 4 | 0 | 3 |
| IFNA2 | GSN-AS1 | 0.627304 | 3 | 0 | 3 |
| IFNA2 | SLPI | 0.619975 | 3 | 0 | 3 |
| IFNA2 | KIR2DS2 | 0.619009 | 4 | 0 | 3 |
| IFNA2 | UBQLN3 | 0.607508 | 3 | 0 | 3 |
| IFNA2 | LINC00563 | 0.60314 | 4 | 0 | 3 |
| IFNA2 | CER1 | 0.600841 | 3 | 0 | 3 |
| IFNA2 | KRTAP9-9 | 0.59789 | 3 | 0 | 3 |
| IFNA2 | C14orf132 | 0.596413 | 3 | 0 | 3 |
| IFNA2 | AMPD1 | 0.594672 | 4 | 0 | 4 |
| IFNA2 | TNFSF11 | 0.593646 | 4 | 0 | 3 |
| IFNA2 | MYO3A | 0.589197 | 3 | 0 | 3 |
| IFNA2 | ACTN2 | 0.584196 | 3 | 0 | 3 |
| IFNA2 | MYO1A | 0.583998 | 5 | 0 | 3 |
| IFNA2 | CRHR2 | 0.582198 | 4 | 0 | 3 |
| IFNA2 | EGOT | 0.581307 | 4 | 0 | 4 |
| IFNA2 | RGSL1 | 0.580843 | 5 | 0 | 3 |
| IFNA2 | SPINK2 | 0.580499 | 4 | 0 | 3 |
| IFNA2 | ADAM20 | 0.5785 | 3 | 0 | 3 |
For details and further investigation, click here
