| Full name: keratin 15 | Alias Symbol: K15|CK15|K1CO | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 3866 | HGNC ID: HGNC:6421 | Ensembl Gene: ENSG00000171346 | OMIM ID: 148030 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT15 | 3866 | 204734_at | -0.9831 | 0.4690 | |
| GSE20347 | KRT15 | 3866 | 204734_at | -1.4238 | 0.0081 | |
| GSE23400 | KRT15 | 3866 | 204734_at | -1.7200 | 0.0000 | |
| GSE26886 | KRT15 | 3866 | 204734_at | -1.7719 | 0.0011 | |
| GSE29001 | KRT15 | 3866 | 204734_at | -2.0042 | 0.0218 | |
| GSE38129 | KRT15 | 3866 | 204734_at | 0.0507 | 0.9528 | |
| GSE45670 | KRT15 | 3866 | 204734_at | -0.4632 | 0.2696 | |
| GSE53622 | KRT15 | 3866 | 3780 | -1.4559 | 0.0000 | |
| GSE53624 | KRT15 | 3866 | 3780 | -2.1191 | 0.0000 | |
| GSE63941 | KRT15 | 3866 | 204734_at | 4.8333 | 0.0045 | |
| GSE77861 | KRT15 | 3866 | 204734_at | -2.3075 | 0.0088 | |
| GSE97050 | KRT15 | 3866 | A_23_P27133 | 0.1261 | 0.8879 | |
| SRP007169 | KRT15 | 3866 | RNAseq | -3.4235 | 0.0000 | |
| SRP008496 | KRT15 | 3866 | RNAseq | -1.7338 | 0.0024 | |
| SRP064894 | KRT15 | 3866 | RNAseq | -1.8309 | 0.0008 | |
| SRP133303 | KRT15 | 3866 | RNAseq | -1.9266 | 0.0001 | |
| SRP159526 | KRT15 | 3866 | RNAseq | -1.9300 | 0.0000 | |
| SRP193095 | KRT15 | 3866 | RNAseq | -1.4465 | 0.0119 | |
| SRP219564 | KRT15 | 3866 | RNAseq | -2.0718 | 0.0889 | |
| TCGA | KRT15 | 3866 | RNAseq | 1.1213 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 13.
Survival by KRT15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT15 | 3866 | 6 | 2 | 22 | |
| GSE20123 | KRT15 | 3866 | 6 | 2 | 22 | |
| GSE43470 | KRT15 | 3866 | 1 | 2 | 40 | |
| GSE46452 | KRT15 | 3866 | 34 | 0 | 25 | |
| GSE47630 | KRT15 | 3866 | 8 | 1 | 31 | |
| GSE54993 | KRT15 | 3866 | 3 | 4 | 63 | |
| GSE54994 | KRT15 | 3866 | 8 | 5 | 40 | |
| GSE60625 | KRT15 | 3866 | 4 | 0 | 7 | |
| GSE74703 | KRT15 | 3866 | 1 | 1 | 34 | |
| GSE74704 | KRT15 | 3866 | 4 | 1 | 15 | |
| TCGA | KRT15 | 3866 | 23 | 7 | 66 |
Total number of gains: 98; Total number of losses: 25; Total Number of normals: 365.
Somatic mutations of KRT15:
Generating mutation plots.
Highly correlated genes for KRT15:
Showing top 20/877 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT15 | UPK3B | 0.787567 | 3 | 0 | 3 |
| KRT15 | SPAG17 | 0.778138 | 3 | 0 | 3 |
| KRT15 | NCCRP1 | 0.770223 | 3 | 0 | 3 |
| KRT15 | MAL2 | 0.759491 | 6 | 0 | 6 |
| KRT15 | KRT13 | 0.754769 | 11 | 0 | 11 |
| KRT15 | GRHL1 | 0.734942 | 5 | 0 | 5 |
| KRT15 | VSIG10L | 0.734356 | 5 | 0 | 5 |
| KRT15 | S100A16 | 0.731874 | 5 | 0 | 5 |
| KRT15 | TMPRSS11A | 0.730211 | 3 | 0 | 3 |
| KRT15 | C15orf48 | 0.730033 | 5 | 0 | 5 |
| KRT15 | TRIM29 | 0.725971 | 10 | 0 | 10 |
| KRT15 | GRHL3 | 0.719218 | 6 | 0 | 6 |
| KRT15 | BNIPL | 0.711114 | 5 | 0 | 5 |
| KRT15 | SPRR1A | 0.708373 | 7 | 0 | 7 |
| KRT15 | SPRR2D | 0.703975 | 3 | 0 | 3 |
| KRT15 | NIPAL1 | 0.69984 | 3 | 0 | 3 |
| KRT15 | CERS3 | 0.699831 | 5 | 0 | 5 |
| KRT15 | SPRR2A | 0.694993 | 3 | 0 | 3 |
| KRT15 | UQCRC1 | 0.694369 | 3 | 0 | 3 |
| KRT15 | A2ML1 | 0.694279 | 6 | 0 | 5 |
For details and further investigation, click here
