| Full name: keratin 75 | Alias Symbol: K6HF | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 9119 | HGNC ID: HGNC:24431 | Ensembl Gene: ENSG00000170454 | OMIM ID: 609025 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT75:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT75 | 9119 | 207065_at | 1.6200 | 0.2840 | |
| GSE20347 | KRT75 | 9119 | 207065_at | 0.7530 | 0.0132 | |
| GSE23400 | KRT75 | 9119 | 207065_at | 0.6818 | 0.0004 | |
| GSE26886 | KRT75 | 9119 | 207065_at | 0.6515 | 0.1239 | |
| GSE29001 | KRT75 | 9119 | 207065_at | 0.7529 | 0.1805 | |
| GSE38129 | KRT75 | 9119 | 207065_at | 1.0275 | 0.0005 | |
| GSE45670 | KRT75 | 9119 | 207065_at | 1.6972 | 0.0236 | |
| GSE53622 | KRT75 | 9119 | 5370 | -0.5391 | 0.1022 | |
| GSE53624 | KRT75 | 9119 | 5370 | -1.2006 | 0.0000 | |
| GSE63941 | KRT75 | 9119 | 207065_at | 0.2883 | 0.4241 | |
| GSE77861 | KRT75 | 9119 | 207065_at | 1.1454 | 0.0903 | |
| GSE97050 | KRT75 | 9119 | A_23_P64854 | 0.6533 | 0.4860 | |
| SRP007169 | KRT75 | 9119 | RNAseq | -1.1269 | 0.2443 | |
| SRP008496 | KRT75 | 9119 | RNAseq | -1.3500 | 0.0580 | |
| SRP133303 | KRT75 | 9119 | RNAseq | 8.0083 | 0.0000 | |
| SRP159526 | KRT75 | 9119 | RNAseq | 4.8859 | 0.0000 | |
| TCGA | KRT75 | 9119 | RNAseq | 2.6526 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by KRT75 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT75:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT75 | 9119 | 8 | 1 | 21 | |
| GSE20123 | KRT75 | 9119 | 8 | 1 | 21 | |
| GSE43470 | KRT75 | 9119 | 3 | 0 | 40 | |
| GSE46452 | KRT75 | 9119 | 7 | 1 | 51 | |
| GSE47630 | KRT75 | 9119 | 10 | 2 | 28 | |
| GSE54993 | KRT75 | 9119 | 0 | 5 | 65 | |
| GSE54994 | KRT75 | 9119 | 5 | 1 | 47 | |
| GSE60625 | KRT75 | 9119 | 0 | 0 | 11 | |
| GSE74703 | KRT75 | 9119 | 3 | 0 | 33 | |
| GSE74704 | KRT75 | 9119 | 5 | 1 | 14 | |
| TCGA | KRT75 | 9119 | 13 | 11 | 72 |
Total number of gains: 62; Total number of losses: 23; Total Number of normals: 403.
Somatic mutations of KRT75:
Generating mutation plots.
Highly correlated genes for KRT75:
Showing top 20/293 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT75 | KRT6C | 0.802363 | 4 | 0 | 3 |
| KRT75 | LAD1 | 0.795661 | 3 | 0 | 3 |
| KRT75 | PGLYRP3 | 0.76996 | 3 | 0 | 3 |
| KRT75 | FAM83C | 0.764381 | 3 | 0 | 3 |
| KRT75 | PRR9 | 0.737689 | 4 | 0 | 4 |
| KRT75 | LPAR5 | 0.719831 | 3 | 0 | 3 |
| KRT75 | SPRR1A | 0.715587 | 3 | 0 | 3 |
| KRT75 | GNA15 | 0.703273 | 4 | 0 | 3 |
| KRT75 | ARAP2 | 0.699821 | 3 | 0 | 3 |
| KRT75 | FAM160A1 | 0.694336 | 3 | 0 | 3 |
| KRT75 | UPP1 | 0.682935 | 4 | 0 | 4 |
| KRT75 | CSNK2A2 | 0.666623 | 3 | 0 | 3 |
| KRT75 | ARSI | 0.666431 | 3 | 0 | 3 |
| KRT75 | SLC39A2 | 0.664965 | 3 | 0 | 3 |
| KRT75 | MSRB1 | 0.662469 | 3 | 0 | 3 |
| KRT75 | TRADD | 0.662073 | 4 | 0 | 3 |
| KRT75 | SDC1 | 0.658138 | 4 | 0 | 3 |
| KRT75 | DSC3 | 0.655561 | 4 | 0 | 3 |
| KRT75 | NCF2 | 0.654816 | 5 | 0 | 5 |
| KRT75 | PERP | 0.649769 | 4 | 0 | 3 |
For details and further investigation, click here
