| Full name: thiosulfate sulfurtransferase | Alias Symbol: RDS | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 7263 | HGNC ID: HGNC:12388 | Ensembl Gene: ENSG00000128311 | OMIM ID: 180370 |
| Drug and gene relationship at DGIdb | |||
Expression of TST:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TST | 7263 | 209605_at | -1.1941 | 0.1185 | |
| GSE20347 | TST | 7263 | 209605_at | -1.2966 | 0.0000 | |
| GSE23400 | TST | 7263 | 209605_at | -1.1741 | 0.0000 | |
| GSE26886 | TST | 7263 | 209605_at | -1.4450 | 0.0000 | |
| GSE29001 | TST | 7263 | 209605_at | -1.5654 | 0.0003 | |
| GSE38129 | TST | 7263 | 209605_at | -0.8747 | 0.0005 | |
| GSE45670 | TST | 7263 | 209605_at | -0.5034 | 0.1306 | |
| GSE53622 | TST | 7263 | 66065 | -1.3656 | 0.0000 | |
| GSE53624 | TST | 7263 | 66065 | -1.4355 | 0.0000 | |
| GSE63941 | TST | 7263 | 209605_at | 0.3598 | 0.6852 | |
| GSE77861 | TST | 7263 | 209605_at | -0.3335 | 0.3753 | |
| GSE97050 | TST | 7263 | A_23_P29248 | -0.0088 | 0.9786 | |
| SRP007169 | TST | 7263 | RNAseq | -2.6480 | 0.0000 | |
| SRP008496 | TST | 7263 | RNAseq | -2.6589 | 0.0000 | |
| SRP064894 | TST | 7263 | RNAseq | -1.4636 | 0.0006 | |
| SRP133303 | TST | 7263 | RNAseq | -1.8387 | 0.0000 | |
| SRP159526 | TST | 7263 | RNAseq | -1.4225 | 0.0004 | |
| SRP193095 | TST | 7263 | RNAseq | -1.7298 | 0.0000 | |
| SRP219564 | TST | 7263 | RNAseq | -1.2955 | 0.0178 | |
| TCGA | TST | 7263 | RNAseq | -0.2610 | 0.0123 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by TST expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TST:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TST | 7263 | 6 | 6 | 18 | |
| GSE20123 | TST | 7263 | 6 | 5 | 19 | |
| GSE43470 | TST | 7263 | 4 | 6 | 33 | |
| GSE46452 | TST | 7263 | 31 | 1 | 27 | |
| GSE47630 | TST | 7263 | 8 | 5 | 27 | |
| GSE54993 | TST | 7263 | 3 | 6 | 61 | |
| GSE54994 | TST | 7263 | 10 | 8 | 35 | |
| GSE60625 | TST | 7263 | 5 | 0 | 6 | |
| GSE74703 | TST | 7263 | 4 | 4 | 28 | |
| GSE74704 | TST | 7263 | 3 | 2 | 15 | |
| TCGA | TST | 7263 | 27 | 16 | 53 |
Total number of gains: 107; Total number of losses: 59; Total Number of normals: 322.
Somatic mutations of TST:
Generating mutation plots.
Highly correlated genes for TST:
Showing top 20/1349 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TST | LTA4H | 0.786946 | 3 | 0 | 3 |
| TST | MPST | 0.783667 | 12 | 0 | 12 |
| TST | GRHL1 | 0.782545 | 6 | 0 | 6 |
| TST | UPK3B | 0.781332 | 3 | 0 | 3 |
| TST | SYTL1 | 0.780109 | 5 | 0 | 5 |
| TST | CAPNS2 | 0.763784 | 4 | 0 | 4 |
| TST | TTC9 | 0.763659 | 11 | 0 | 11 |
| TST | CHP1 | 0.756353 | 9 | 0 | 9 |
| TST | CLIC3 | 0.755243 | 8 | 0 | 8 |
| TST | LIPH | 0.748905 | 7 | 0 | 7 |
| TST | TMEM45B | 0.748183 | 7 | 0 | 6 |
| TST | A2ML1 | 0.748143 | 6 | 0 | 6 |
| TST | CYP2C18 | 0.747957 | 11 | 0 | 10 |
| TST | GDPD3 | 0.747166 | 11 | 0 | 10 |
| TST | CBR3-AS1 | 0.747046 | 4 | 0 | 4 |
| TST | KLK13 | 0.746697 | 10 | 0 | 10 |
| TST | SAMD5 | 0.744952 | 6 | 0 | 6 |
| TST | ASPG | 0.742744 | 5 | 0 | 4 |
| TST | NIPAL1 | 0.74267 | 3 | 0 | 3 |
| TST | ZDHHC13 | 0.74256 | 11 | 0 | 10 |
For details and further investigation, click here
