| Full name: metallothionein 1G | Alias Symbol: MT1K | ||
| Type: protein-coding gene | Cytoband: 16q13 | ||
| Entrez ID: 4495 | HGNC ID: HGNC:7399 | Ensembl Gene: ENSG00000125144 | OMIM ID: 156353 |
| Drug and gene relationship at DGIdb | |||
Expression of MT1G:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MT1G | 4495 | 204745_x_at | -0.0840 | 0.9319 | |
| GSE20347 | MT1G | 4495 | 204745_x_at | 0.0781 | 0.8103 | |
| GSE23400 | MT1G | 4495 | 204745_x_at | -0.4973 | 0.0007 | |
| GSE26886 | MT1G | 4495 | 204745_x_at | -0.4967 | 0.4842 | |
| GSE29001 | MT1G | 4495 | 204745_x_at | -0.3872 | 0.1550 | |
| GSE38129 | MT1G | 4495 | 204745_x_at | -0.2334 | 0.4793 | |
| GSE45670 | MT1G | 4495 | 204745_x_at | -0.8843 | 0.0152 | |
| GSE63941 | MT1G | 4495 | 204745_x_at | -1.1998 | 0.1255 | |
| GSE77861 | MT1G | 4495 | 204745_x_at | -0.9427 | 0.0971 | |
| GSE97050 | MT1G | 4495 | A_33_P3233645 | -1.8169 | 0.1812 | |
| SRP007169 | MT1G | 4495 | RNAseq | -4.5907 | 0.0038 | |
| SRP064894 | MT1G | 4495 | RNAseq | -3.7189 | 0.0000 | |
| SRP133303 | MT1G | 4495 | RNAseq | -3.5461 | 0.0000 | |
| SRP219564 | MT1G | 4495 | RNAseq | -2.1742 | 0.0131 | |
| TCGA | MT1G | 4495 | RNAseq | -1.6797 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by MT1G expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MT1G:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MT1G | 4495 | 5 | 0 | 25 | |
| GSE20123 | MT1G | 4495 | 5 | 1 | 24 | |
| GSE43470 | MT1G | 4495 | 2 | 7 | 34 | |
| GSE46452 | MT1G | 4495 | 38 | 1 | 20 | |
| GSE47630 | MT1G | 4495 | 10 | 8 | 22 | |
| GSE54993 | MT1G | 4495 | 2 | 4 | 64 | |
| GSE54994 | MT1G | 4495 | 7 | 10 | 36 | |
| GSE60625 | MT1G | 4495 | 4 | 0 | 7 | |
| GSE74703 | MT1G | 4495 | 2 | 4 | 30 | |
| GSE74704 | MT1G | 4495 | 4 | 0 | 16 | |
| TCGA | MT1G | 4495 | 25 | 13 | 58 |
Total number of gains: 104; Total number of losses: 48; Total Number of normals: 336.
Somatic mutations of MT1G:
Generating mutation plots.
Highly correlated genes for MT1G:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MT1G | MT1HL1 | 0.929102 | 9 | 0 | 9 |
| MT1G | MT1H | 0.907491 | 11 | 0 | 10 |
| MT1G | MT1F | 0.86156 | 11 | 0 | 10 |
| MT1G | MT2A | 0.838757 | 10 | 0 | 9 |
| MT1G | MT1X | 0.805959 | 11 | 0 | 9 |
| MT1G | MT1E | 0.725432 | 10 | 0 | 9 |
| MT1G | AK5 | 0.657465 | 4 | 0 | 3 |
| MT1G | SFXN3 | 0.657156 | 3 | 0 | 3 |
| MT1G | SPATA3-AS1 | 0.642887 | 3 | 0 | 3 |
| MT1G | FAM187B | 0.64071 | 3 | 0 | 3 |
| MT1G | RSU1 | 0.632901 | 3 | 0 | 3 |
| MT1G | LEPROT | 0.626034 | 4 | 0 | 3 |
| MT1G | C1orf167 | 0.616705 | 3 | 0 | 3 |
| MT1G | HSPA2 | 0.614196 | 5 | 0 | 5 |
| MT1G | TAC1 | 0.606514 | 3 | 0 | 3 |
| MT1G | MT1M | 0.601151 | 10 | 0 | 7 |
| MT1G | EDN3 | 0.599337 | 4 | 0 | 3 |
| MT1G | DMRTA1 | 0.581754 | 3 | 0 | 3 |
| MT1G | ANG | 0.570149 | 3 | 0 | 3 |
| MT1G | SGMS2 | 0.560934 | 4 | 0 | 3 |
For details and further investigation, click here
