| Full name: kinesin family member C3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q21 | ||
| Entrez ID: 3801 | HGNC ID: HGNC:6326 | Ensembl Gene: ENSG00000140859 | OMIM ID: 604535 |
| Drug and gene relationship at DGIdb | |||
Expression of KIFC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIFC3 | 3801 | 209661_at | -0.0366 | 0.9510 | |
| GSE20347 | KIFC3 | 3801 | 209661_at | -0.1186 | 0.3613 | |
| GSE23400 | KIFC3 | 3801 | 209661_at | -0.1540 | 0.0193 | |
| GSE26886 | KIFC3 | 3801 | 209661_at | 0.1838 | 0.4910 | |
| GSE29001 | KIFC3 | 3801 | 209661_at | -0.0989 | 0.8037 | |
| GSE38129 | KIFC3 | 3801 | 209661_at | -0.0447 | 0.7405 | |
| GSE45670 | KIFC3 | 3801 | 1559759_at | 0.6567 | 0.0032 | |
| GSE53622 | KIFC3 | 3801 | 99437 | 0.0598 | 0.6611 | |
| GSE53624 | KIFC3 | 3801 | 99437 | 0.1109 | 0.2799 | |
| GSE63941 | KIFC3 | 3801 | 209661_at | -0.5507 | 0.1948 | |
| GSE77861 | KIFC3 | 3801 | 209661_at | 0.0925 | 0.5939 | |
| GSE97050 | KIFC3 | 3801 | A_23_P54576 | 0.1566 | 0.4898 | |
| SRP007169 | KIFC3 | 3801 | RNAseq | -1.2354 | 0.0516 | |
| SRP008496 | KIFC3 | 3801 | RNAseq | -1.2154 | 0.0006 | |
| SRP064894 | KIFC3 | 3801 | RNAseq | -0.0511 | 0.8213 | |
| SRP133303 | KIFC3 | 3801 | RNAseq | 0.0381 | 0.8704 | |
| SRP159526 | KIFC3 | 3801 | RNAseq | -0.1821 | 0.6130 | |
| SRP193095 | KIFC3 | 3801 | RNAseq | 0.0522 | 0.8271 | |
| SRP219564 | KIFC3 | 3801 | RNAseq | -0.6655 | 0.0002 | |
| TCGA | KIFC3 | 3801 | RNAseq | 0.0968 | 0.3012 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KIFC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIFC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIFC3 | 3801 | 6 | 0 | 24 | |
| GSE20123 | KIFC3 | 3801 | 6 | 1 | 23 | |
| GSE43470 | KIFC3 | 3801 | 2 | 6 | 35 | |
| GSE46452 | KIFC3 | 3801 | 38 | 1 | 20 | |
| GSE47630 | KIFC3 | 3801 | 10 | 8 | 22 | |
| GSE54993 | KIFC3 | 3801 | 2 | 4 | 64 | |
| GSE54994 | KIFC3 | 3801 | 6 | 10 | 37 | |
| GSE60625 | KIFC3 | 3801 | 4 | 0 | 7 | |
| GSE74703 | KIFC3 | 3801 | 2 | 4 | 30 | |
| GSE74704 | KIFC3 | 3801 | 5 | 0 | 15 | |
| TCGA | KIFC3 | 3801 | 26 | 12 | 58 |
Total number of gains: 107; Total number of losses: 46; Total Number of normals: 335.
Somatic mutations of KIFC3:
Generating mutation plots.
Highly correlated genes for KIFC3:
Showing top 20/77 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIFC3 | MT1X | 0.676492 | 3 | 0 | 3 |
| KIFC3 | MT1HL1 | 0.633418 | 3 | 0 | 3 |
| KIFC3 | MFSD10 | 0.63011 | 3 | 0 | 3 |
| KIFC3 | MT1H | 0.612131 | 3 | 0 | 3 |
| KIFC3 | MAN1B1 | 0.602998 | 3 | 0 | 3 |
| KIFC3 | MT1F | 0.594873 | 3 | 0 | 3 |
| KIFC3 | SMOX | 0.592659 | 4 | 0 | 3 |
| KIFC3 | TGFB2 | 0.568923 | 3 | 0 | 3 |
| KIFC3 | YIPF5 | 0.566742 | 5 | 0 | 4 |
| KIFC3 | PLEC | 0.563175 | 4 | 0 | 3 |
| KIFC3 | DLG4 | 0.563174 | 5 | 0 | 3 |
| KIFC3 | HMOX2 | 0.562308 | 4 | 0 | 3 |
| KIFC3 | APOL2 | 0.562179 | 4 | 0 | 4 |
| KIFC3 | LIMK1 | 0.560109 | 3 | 0 | 3 |
| KIFC3 | AFAP1L2 | 0.56003 | 5 | 0 | 3 |
| KIFC3 | NXPH4 | 0.555405 | 4 | 0 | 3 |
| KIFC3 | MT2A | 0.554857 | 6 | 0 | 4 |
| KIFC3 | DUSP10 | 0.554425 | 5 | 0 | 3 |
| KIFC3 | PDLIM7 | 0.552433 | 5 | 0 | 3 |
| KIFC3 | GDAP1L1 | 0.552399 | 5 | 0 | 3 |
For details and further investigation, click here
