| Full name: galectin 3 binding protein | Alias Symbol: MAC-2-BP|90K|BTBD17B|TANGO10B|M2BP|gp90|CyCAP | ||
| Type: protein-coding gene | Cytoband: 17q25 | ||
| Entrez ID: 3959 | HGNC ID: HGNC:6564 | Ensembl Gene: ENSG00000108679 | OMIM ID: 600626 |
| Drug and gene relationship at DGIdb | |||
Expression of LGALS3BP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LGALS3BP | 3959 | 200923_at | 0.5583 | 0.1169 | |
| GSE20347 | LGALS3BP | 3959 | 200923_at | 0.3423 | 0.0632 | |
| GSE23400 | LGALS3BP | 3959 | 200923_at | 0.6651 | 0.0000 | |
| GSE26886 | LGALS3BP | 3959 | 200923_at | 0.3940 | 0.4281 | |
| GSE29001 | LGALS3BP | 3959 | 200923_at | 0.9011 | 0.0060 | |
| GSE38129 | LGALS3BP | 3959 | 200923_at | 0.4506 | 0.0020 | |
| GSE45670 | LGALS3BP | 3959 | 200923_at | 0.9798 | 0.0001 | |
| GSE53622 | LGALS3BP | 3959 | 27265 | 0.8253 | 0.0000 | |
| GSE53624 | LGALS3BP | 3959 | 27265 | 0.9515 | 0.0000 | |
| GSE63941 | LGALS3BP | 3959 | 200923_at | 1.6473 | 0.0483 | |
| GSE77861 | LGALS3BP | 3959 | 200923_at | 0.6622 | 0.0597 | |
| GSE97050 | LGALS3BP | 3959 | A_23_P15357 | 1.0931 | 0.0727 | |
| SRP007169 | LGALS3BP | 3959 | RNAseq | 0.7114 | 0.0366 | |
| SRP008496 | LGALS3BP | 3959 | RNAseq | 0.3834 | 0.0531 | |
| SRP064894 | LGALS3BP | 3959 | RNAseq | 1.2912 | 0.0000 | |
| SRP133303 | LGALS3BP | 3959 | RNAseq | 0.7775 | 0.0000 | |
| SRP159526 | LGALS3BP | 3959 | RNAseq | 0.6085 | 0.1211 | |
| SRP193095 | LGALS3BP | 3959 | RNAseq | 0.5052 | 0.0515 | |
| SRP219564 | LGALS3BP | 3959 | RNAseq | 1.2520 | 0.0242 | |
| TCGA | LGALS3BP | 3959 | RNAseq | 0.0539 | 0.3057 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by LGALS3BP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LGALS3BP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LGALS3BP | 3959 | 4 | 3 | 23 | |
| GSE20123 | LGALS3BP | 3959 | 4 | 3 | 23 | |
| GSE43470 | LGALS3BP | 3959 | 3 | 4 | 36 | |
| GSE46452 | LGALS3BP | 3959 | 33 | 0 | 26 | |
| GSE47630 | LGALS3BP | 3959 | 8 | 1 | 31 | |
| GSE54993 | LGALS3BP | 3959 | 2 | 5 | 63 | |
| GSE54994 | LGALS3BP | 3959 | 10 | 5 | 38 | |
| GSE60625 | LGALS3BP | 3959 | 6 | 0 | 5 | |
| GSE74703 | LGALS3BP | 3959 | 3 | 2 | 31 | |
| GSE74704 | LGALS3BP | 3959 | 4 | 3 | 13 | |
| TCGA | LGALS3BP | 3959 | 30 | 9 | 57 |
Total number of gains: 107; Total number of losses: 35; Total Number of normals: 346.
Somatic mutations of LGALS3BP:
Generating mutation plots.
Highly correlated genes for LGALS3BP:
Showing top 20/729 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LGALS3BP | USP41 | 0.710468 | 3 | 0 | 3 |
| LGALS3BP | CD80 | 0.679593 | 3 | 0 | 3 |
| LGALS3BP | ARHGEF16 | 0.666368 | 4 | 0 | 3 |
| LGALS3BP | TTYH3 | 0.661663 | 7 | 0 | 7 |
| LGALS3BP | RNF213 | 0.659074 | 4 | 0 | 4 |
| LGALS3BP | PTK7 | 0.658794 | 9 | 0 | 8 |
| LGALS3BP | IFI35 | 0.658542 | 12 | 0 | 11 |
| LGALS3BP | LY6E | 0.6584 | 12 | 0 | 9 |
| LGALS3BP | OAS3 | 0.657413 | 12 | 0 | 11 |
| LGALS3BP | C4orf48 | 0.653817 | 6 | 0 | 6 |
| LGALS3BP | AGTRAP | 0.646013 | 5 | 0 | 4 |
| LGALS3BP | PARP12 | 0.645521 | 11 | 0 | 9 |
| LGALS3BP | UBE2L6 | 0.645013 | 13 | 0 | 11 |
| LGALS3BP | DTX3L | 0.6446 | 8 | 0 | 6 |
| LGALS3BP | GSDMD | 0.644149 | 10 | 0 | 8 |
| LGALS3BP | UTP23 | 0.641684 | 4 | 0 | 4 |
| LGALS3BP | HSP90B1 | 0.641625 | 6 | 0 | 5 |
| LGALS3BP | STAT1 | 0.639278 | 10 | 0 | 9 |
| LGALS3BP | TONSL | 0.638236 | 5 | 0 | 4 |
| LGALS3BP | TRIM47 | 0.636776 | 5 | 0 | 5 |
For details and further investigation, click here
