| Full name: solute carrier family 25 member 22 | Alias Symbol: GC1|FLJ13044|NET44|EIEE3 | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 79751 | HGNC ID: HGNC:19954 | Ensembl Gene: ENSG00000177542 | OMIM ID: 609302 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC25A22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC25A22 | 79751 | 218725_at | 0.7242 | 0.0103 | |
| GSE20347 | SLC25A22 | 79751 | 218725_at | 0.2591 | 0.0023 | |
| GSE23400 | SLC25A22 | 79751 | 218725_at | 0.2282 | 0.0000 | |
| GSE26886 | SLC25A22 | 79751 | 218725_at | 0.2420 | 0.1489 | |
| GSE29001 | SLC25A22 | 79751 | 218725_at | 0.3534 | 0.1891 | |
| GSE38129 | SLC25A22 | 79751 | 218725_at | 0.2687 | 0.0003 | |
| GSE45670 | SLC25A22 | 79751 | 218725_at | 0.3750 | 0.0011 | |
| GSE53622 | SLC25A22 | 79751 | 24727 | 0.4670 | 0.0014 | |
| GSE53624 | SLC25A22 | 79751 | 24727 | 0.8197 | 0.0000 | |
| GSE63941 | SLC25A22 | 79751 | 218725_at | 0.2646 | 0.3987 | |
| GSE77861 | SLC25A22 | 79751 | 218725_at | 0.1328 | 0.4531 | |
| GSE97050 | SLC25A22 | 79751 | A_23_P409386 | 0.3172 | 0.4057 | |
| SRP007169 | SLC25A22 | 79751 | RNAseq | 0.5565 | 0.1896 | |
| SRP008496 | SLC25A22 | 79751 | RNAseq | 0.2227 | 0.4210 | |
| SRP064894 | SLC25A22 | 79751 | RNAseq | 0.6112 | 0.0064 | |
| SRP133303 | SLC25A22 | 79751 | RNAseq | 0.7409 | 0.0001 | |
| SRP159526 | SLC25A22 | 79751 | RNAseq | 0.1932 | 0.5008 | |
| SRP193095 | SLC25A22 | 79751 | RNAseq | 0.6677 | 0.0002 | |
| SRP219564 | SLC25A22 | 79751 | RNAseq | 1.1429 | 0.0225 | |
| TCGA | SLC25A22 | 79751 | RNAseq | 0.2341 | 0.0009 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLC25A22 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC25A22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC25A22 | 79751 | 1 | 11 | 18 | |
| GSE20123 | SLC25A22 | 79751 | 1 | 12 | 17 | |
| GSE43470 | SLC25A22 | 79751 | 1 | 10 | 32 | |
| GSE46452 | SLC25A22 | 79751 | 7 | 8 | 44 | |
| GSE47630 | SLC25A22 | 79751 | 4 | 12 | 24 | |
| GSE54993 | SLC25A22 | 79751 | 3 | 1 | 66 | |
| GSE54994 | SLC25A22 | 79751 | 1 | 12 | 40 | |
| GSE60625 | SLC25A22 | 79751 | 0 | 0 | 11 | |
| GSE74703 | SLC25A22 | 79751 | 1 | 8 | 27 | |
| GSE74704 | SLC25A22 | 79751 | 0 | 8 | 12 | |
| TCGA | SLC25A22 | 79751 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 120; Total Number of normals: 341.
Somatic mutations of SLC25A22:
Generating mutation plots.
Highly correlated genes for SLC25A22:
Showing top 20/894 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC25A22 | NAV1 | 0.719492 | 3 | 0 | 3 |
| SLC25A22 | OTX1 | 0.693959 | 3 | 0 | 3 |
| SLC25A22 | MRPL14 | 0.680418 | 5 | 0 | 4 |
| SLC25A22 | PHLDA2 | 0.663881 | 4 | 0 | 4 |
| SLC25A22 | ARHGEF11 | 0.659431 | 3 | 0 | 3 |
| SLC25A22 | TLCD1 | 0.65826 | 4 | 0 | 3 |
| SLC25A22 | FAM89B | 0.637455 | 5 | 0 | 3 |
| SLC25A22 | TCF7L1 | 0.636416 | 3 | 0 | 3 |
| SLC25A22 | BCL2L12 | 0.634919 | 4 | 0 | 4 |
| SLC25A22 | CORO1B | 0.63433 | 3 | 0 | 3 |
| SLC25A22 | PSMG3 | 0.632065 | 6 | 0 | 6 |
| SLC25A22 | SIPA1 | 0.631967 | 5 | 0 | 4 |
| SLC25A22 | CEP78 | 0.631076 | 4 | 0 | 3 |
| SLC25A22 | UHRF1 | 0.630049 | 6 | 0 | 4 |
| SLC25A22 | TNFSF13 | 0.625504 | 3 | 0 | 3 |
| SLC25A22 | SMARCD2 | 0.624076 | 3 | 0 | 3 |
| SLC25A22 | GPATCH4 | 0.624038 | 4 | 0 | 4 |
| SLC25A22 | CHEK1 | 0.621216 | 8 | 0 | 6 |
| SLC25A22 | EME1 | 0.619731 | 5 | 0 | 3 |
| SLC25A22 | ZC3HC1 | 0.619043 | 5 | 0 | 4 |
For details and further investigation, click here
