NBR2

 

Full name: neighbor of BRCA1 lncRNA 2 Alias Symbol: NCRNA00192
Type: non-coding RNA Cytoband: 17q21.31
Entrez ID: 10230 HGNC ID: HGNC:20691 Ensembl Gene: ENSG00000198496 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of NBR2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NBR2 10230 1553992_s_at 0.0079 0.9830
GSE20347 NBR2 10230 207631_at 0.2326 0.0093
GSE23400 NBR2 10230 207631_at 0.0615 0.1359
GSE26886 NBR2 10230 1553992_s_at -0.3335 0.2602
GSE29001 NBR2 10230 207631_at 0.4920 0.0598
GSE38129 NBR2 10230 207631_at 0.2153 0.0132
GSE45670 NBR2 10230 1553992_s_at 0.3560 0.0882
GSE63941 NBR2 10230 1553992_s_at 1.1366 0.0728
GSE77861 NBR2 10230 207631_at 0.1050 0.4003
SRP007169 NBR2 10230 RNAseq 0.5927 0.3751
SRP064894 NBR2 10230 RNAseq 0.4913 0.0136
SRP133303 NBR2 10230 RNAseq 0.0362 0.8009
SRP159526 NBR2 10230 RNAseq 0.4336 0.1658
SRP193095 NBR2 10230 RNAseq 0.2079 0.1108
SRP219564 NBR2 10230 RNAseq 0.5400 0.1883
TCGA NBR2 10230 RNAseq -0.0716 0.4495

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by NBR2 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of NBR2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NBR2 10230 6 2 22
GSE20123 NBR2 10230 6 2 22
GSE43470 NBR2 10230 1 2 40
GSE46452 NBR2 10230 34 0 25
GSE47630 NBR2 10230 8 1 31
GSE54993 NBR2 10230 3 4 63
GSE54994 NBR2 10230 8 5 40
GSE60625 NBR2 10230 4 0 7
GSE74703 NBR2 10230 1 1 34
GSE74704 NBR2 10230 4 1 15
TCGA NBR2 10230 22 7 67

Total number of gains: 97; Total number of losses: 25; Total Number of normals: 366.  


 

Somatic mutations of NBR2:

 

Generating mutation plots.

 

Highly correlated genes for NBR2:

 

Showing top 20/44 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NBR2MNX10.647231303
NBR2WDR60.645173303
NBR2RAB11FIP30.634112303
NBR2PHC30.62764404
NBR2ARID5A0.61606403
NBR2COLEC110.614062504
NBR2CALML40.612669403
NBR2PRR110.600885403
NBR2HAUS50.599357404
NBR2NXF10.592279303
NBR2OGDHL0.589471404
NBR2FREM20.582961303
NBR2GSDMB0.56924503
NBR2AXIN10.565786403
NBR2NDE10.56147403
NBR2HOXB90.560878303
NBR2TTF10.557905605
NBR2DDX110.556798504
NBR2APBA20.55675503
NBR2AKT20.55576403

For details and further investigation, click here