UNC119B

 

Full name: unc-119 lipid binding chaperone B Alias Symbol: MGC5139|POC7B
Type: protein-coding gene Cytoband: 12q24.31
Entrez ID: 84747 HGNC ID: HGNC:16488 Ensembl Gene: ENSG00000175970 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of UNC119B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UNC119B 84747 202365_at 0.9002 0.0958
GSE20347 UNC119B 84747 202365_at -0.0032 0.9856
GSE23400 UNC119B 84747 202365_at 0.2093 0.0003
GSE26886 UNC119B 84747 202365_at -0.6177 0.0055
GSE29001 UNC119B 84747 202365_at 0.1339 0.6835
GSE38129 UNC119B 84747 202365_at 0.0343 0.8083
GSE45670 UNC119B 84747 202365_at 0.1788 0.1251
GSE53622 UNC119B 84747 29059 0.2169 0.0596
GSE53624 UNC119B 84747 29059 0.2945 0.0020
GSE63941 UNC119B 84747 202365_at 0.0240 0.9442
GSE77861 UNC119B 84747 202365_at 0.1023 0.7096
GSE97050 UNC119B 84747 A_23_P87827 0.0507 0.8862
SRP007169 UNC119B 84747 RNAseq 0.0935 0.7936
SRP008496 UNC119B 84747 RNAseq 0.4330 0.0705
SRP064894 UNC119B 84747 RNAseq 0.0648 0.6347
SRP133303 UNC119B 84747 RNAseq -0.1474 0.3918
SRP159526 UNC119B 84747 RNAseq 0.3118 0.1729
SRP193095 UNC119B 84747 RNAseq 0.1088 0.2326
SRP219564 UNC119B 84747 RNAseq -0.2820 0.3309
TCGA UNC119B 84747 RNAseq -0.1591 0.0149

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by UNC119B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of UNC119B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UNC119B 84747 6 2 22
GSE20123 UNC119B 84747 6 2 22
GSE43470 UNC119B 84747 2 2 39
GSE46452 UNC119B 84747 9 1 49
GSE47630 UNC119B 84747 9 3 28
GSE54993 UNC119B 84747 0 5 65
GSE54994 UNC119B 84747 7 6 40
GSE60625 UNC119B 84747 0 0 11
GSE74703 UNC119B 84747 2 1 33
GSE74704 UNC119B 84747 3 2 15
TCGA UNC119B 84747 20 11 65

Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.  

 

Somatic mutations of UNC119B:

 

Generating mutation plots.

 

Highly correlated genes for UNC119B:

 

Showing top 20/304 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UNC119BNR2C20.727908303
UNC119BKCTD150.719447303
UNC119BRNF130.71233303
UNC119BNEURL1B0.703775303
UNC119BPARL0.694073303
UNC119BEMP20.68783303
UNC119BIP6K10.681969303
UNC119BSWT10.680335303
UNC119BHDAC10.675489303
UNC119BTTC40.672709303
UNC119BC2CD20.666149303
UNC119BFAM102B0.665903303
UNC119BDDX200.663417303
UNC119BPQBP10.663209303
UNC119BMIB10.661709403
UNC119BATG4C0.657714303
UNC119BNDUFS20.653164504
UNC119BTPD520.651767403
UNC119BRIOK20.647777303
UNC119BSBNO10.645158504

For details and further investigation, click here