| Full name: neuronal regeneration related protein | Alias Symbol: P311|D4S114|PRO1873|PTZ17|SEZ17 | ||
| Type: protein-coding gene | Cytoband: 5q22.1 | ||
| Entrez ID: 9315 | HGNC ID: HGNC:16834 | Ensembl Gene: ENSG00000134986 | OMIM ID: 607332 |
| Drug and gene relationship at DGIdb | |||
Expression of NREP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NREP | 9315 | 201310_s_at | 1.3081 | 0.1156 | |
| GSE20347 | NREP | 9315 | 201310_s_at | 1.1088 | 0.0003 | |
| GSE23400 | NREP | 9315 | 201310_s_at | 1.1577 | 0.0000 | |
| GSE26886 | NREP | 9315 | 201310_s_at | 1.4840 | 0.0000 | |
| GSE29001 | NREP | 9315 | 201310_s_at | 0.9319 | 0.0735 | |
| GSE38129 | NREP | 9315 | 201310_s_at | 1.0425 | 0.0001 | |
| GSE45670 | NREP | 9315 | 201310_s_at | 0.5508 | 0.1215 | |
| GSE53622 | NREP | 9315 | 8920 | 1.3306 | 0.0000 | |
| GSE53624 | NREP | 9315 | 8920 | 1.5170 | 0.0000 | |
| GSE63941 | NREP | 9315 | 201310_s_at | -3.4332 | 0.0440 | |
| GSE77861 | NREP | 9315 | 201310_s_at | 0.2137 | 0.6583 | |
| SRP007169 | NREP | 9315 | RNAseq | 1.7511 | 0.0002 | |
| SRP008496 | NREP | 9315 | RNAseq | 2.0236 | 0.0000 | |
| SRP064894 | NREP | 9315 | RNAseq | 1.6093 | 0.0000 | |
| SRP133303 | NREP | 9315 | RNAseq | 1.6849 | 0.0000 | |
| SRP159526 | NREP | 9315 | RNAseq | 1.0817 | 0.0098 | |
| SRP193095 | NREP | 9315 | RNAseq | 1.2452 | 0.0000 | |
| SRP219564 | NREP | 9315 | RNAseq | 1.3622 | 0.0323 |
Upregulated datasets: 13; Downregulated datasets: 1.
Survival by NREP expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of NREP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NREP | 9315 | 1 | 13 | 16 | |
| GSE20123 | NREP | 9315 | 1 | 13 | 16 | |
| GSE43470 | NREP | 9315 | 3 | 8 | 32 | |
| GSE46452 | NREP | 9315 | 0 | 28 | 31 | |
| GSE47630 | NREP | 9315 | 0 | 21 | 19 | |
| GSE54993 | NREP | 9315 | 9 | 1 | 60 | |
| GSE54994 | NREP | 9315 | 1 | 17 | 35 | |
| GSE60625 | NREP | 9315 | 0 | 0 | 11 | |
| GSE74703 | NREP | 9315 | 2 | 6 | 28 | |
| GSE74704 | NREP | 9315 | 1 | 7 | 12 | |
| TCGA | NREP | 9315 | 2 | 41 | 53 |
Total number of gains: 20; Total number of losses: 155; Total Number of normals: 313.
Somatic mutations of NREP:
Generating mutation plots.
Highly correlated genes for NREP:
Showing top 20/872 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NREP | C1QTNF6 | 0.763594 | 4 | 0 | 4 |
| NREP | COL5A1 | 0.716716 | 11 | 0 | 10 |
| NREP | COL5A2 | 0.716497 | 11 | 0 | 10 |
| NREP | CDH11 | 0.712437 | 10 | 0 | 9 |
| NREP | LGALS1 | 0.712314 | 9 | 0 | 9 |
| NREP | MMD | 0.704381 | 10 | 0 | 10 |
| NREP | ADAMTS2 | 0.701326 | 6 | 0 | 6 |
| NREP | RHOBTB1 | 0.698839 | 11 | 0 | 10 |
| NREP | VCAN | 0.697256 | 11 | 0 | 9 |
| NREP | PXDN | 0.695189 | 11 | 0 | 10 |
| NREP | HTRA1 | 0.692295 | 11 | 0 | 11 |
| NREP | HOXC9 | 0.687202 | 3 | 0 | 3 |
| NREP | GXYLT2 | 0.682843 | 6 | 0 | 6 |
| NREP | COL3A1 | 0.682624 | 11 | 0 | 10 |
| NREP | COL1A1 | 0.682615 | 10 | 0 | 9 |
| NREP | CTHRC1 | 0.682148 | 7 | 0 | 6 |
| NREP | COL4A1 | 0.681991 | 11 | 0 | 10 |
| NREP | MFAP2 | 0.681808 | 11 | 0 | 11 |
| NREP | FKBP7 | 0.681101 | 5 | 0 | 5 |
| NREP | TGFBI | 0.680053 | 10 | 0 | 10 |
For details and further investigation, click here
