NUP85

 

Full name: nucleoporin 85 Alias Symbol: NUP75|FLJ12549
Type: protein-coding gene Cytoband: 17q25
Entrez ID: 79902 HGNC ID: HGNC:8734 Ensembl Gene: ENSG00000125450 OMIM ID: 170285
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of NUP85:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NUP85 79902 218014_at 0.5746 0.1270
GSE20347 NUP85 79902 218014_at 0.5458 0.0005
GSE23400 NUP85 79902 218014_at 0.8495 0.0000
GSE26886 NUP85 79902 218014_at 0.3436 0.0105
GSE29001 NUP85 79902 218014_at 0.5975 0.0388
GSE38129 NUP85 79902 218014_at 0.7570 0.0000
GSE45670 NUP85 79902 218014_at 0.5346 0.0040
GSE53622 NUP85 79902 34139 0.5790 0.0000
GSE53624 NUP85 79902 34139 0.7653 0.0000
GSE63941 NUP85 79902 218014_at 1.2865 0.0088
GSE77861 NUP85 79902 218014_at 0.9048 0.0011
GSE97050 NUP85 79902 A_23_P26777 0.4984 0.1929
SRP007169 NUP85 79902 RNAseq 0.8725 0.0234
SRP008496 NUP85 79902 RNAseq 0.6192 0.0220
SRP064894 NUP85 79902 RNAseq 0.9905 0.0000
SRP133303 NUP85 79902 RNAseq 0.8687 0.0002
SRP159526 NUP85 79902 RNAseq 0.7156 0.0101
SRP193095 NUP85 79902 RNAseq 0.4687 0.0000
SRP219564 NUP85 79902 RNAseq 0.7720 0.0749
TCGA NUP85 79902 RNAseq 0.2740 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by NUP85 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NUP85:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NUP85 79902 6 2 22
GSE20123 NUP85 79902 6 2 22
GSE43470 NUP85 79902 5 3 35
GSE46452 NUP85 79902 33 0 26
GSE47630 NUP85 79902 8 1 31
GSE54993 NUP85 79902 2 5 63
GSE54994 NUP85 79902 10 4 39
GSE60625 NUP85 79902 6 0 5
GSE74703 NUP85 79902 5 1 30
GSE74704 NUP85 79902 4 1 15
TCGA NUP85 79902 32 10 54

Total number of gains: 117; Total number of losses: 29; Total Number of normals: 342.  

 

Somatic mutations of NUP85:

 

Generating mutation plots.

 

Highly correlated genes for NUP85:

 

Showing top 20/1726 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NUP85EME10.753788606
NUP85CENPW0.752424707
NUP85MMS22L0.734857303
NUP85UBE2C0.72658512011
NUP85GINS10.72642412011
NUP85ATAD20.72586111011
NUP85BIRC50.72486112011
NUP85TPX20.72466913012
NUP85NCAPG20.72409211010
NUP85UBE2T0.723583807
NUP85NOL110.7229412011
NUP85KIF2C0.72172912011
NUP85ESCO20.721045706
NUP85SNRPE0.72053910010
NUP85FAM89A0.719548303
NUP85DTL0.71918911010
NUP85KPNA20.718146908
NUP85DNAJC90.716806807
NUP85ACLY0.71555710010
NUP85TOP2A0.71521812011

For details and further investigation, click here