| Full name: APC down-regulated 1 | Alias Symbol: B7323 | ||
| Type: protein-coding gene | Cytoband: 18p11.22 | ||
| Entrez ID: 147495 | HGNC ID: HGNC:15718 | Ensembl Gene: ENSG00000154856 | OMIM ID: 607479 |
| Drug and gene relationship at DGIdb | |||
Expression of APCDD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APCDD1 | 147495 | 225016_at | -0.3555 | 0.7678 | |
| GSE26886 | APCDD1 | 147495 | 225016_at | -0.0403 | 0.9388 | |
| GSE45670 | APCDD1 | 147495 | 225016_at | -0.3367 | 0.2693 | |
| GSE53622 | APCDD1 | 147495 | 123488 | -0.5912 | 0.0000 | |
| GSE53624 | APCDD1 | 147495 | 123488 | -0.7796 | 0.0000 | |
| GSE63941 | APCDD1 | 147495 | 225016_at | 2.0881 | 0.1545 | |
| GSE77861 | APCDD1 | 147495 | 225016_at | -0.6634 | 0.0472 | |
| GSE97050 | APCDD1 | 147495 | A_23_P337262 | -0.5252 | 0.1810 | |
| SRP007169 | APCDD1 | 147495 | RNAseq | -2.6092 | 0.0000 | |
| SRP008496 | APCDD1 | 147495 | RNAseq | -1.1805 | 0.0030 | |
| SRP064894 | APCDD1 | 147495 | RNAseq | -0.6004 | 0.0756 | |
| SRP133303 | APCDD1 | 147495 | RNAseq | -0.8445 | 0.0010 | |
| SRP159526 | APCDD1 | 147495 | RNAseq | -1.0423 | 0.0135 | |
| SRP193095 | APCDD1 | 147495 | RNAseq | -0.1057 | 0.6947 | |
| SRP219564 | APCDD1 | 147495 | RNAseq | -1.0252 | 0.1142 | |
| TCGA | APCDD1 | 147495 | RNAseq | 0.0971 | 0.3760 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by APCDD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APCDD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APCDD1 | 147495 | 6 | 3 | 21 | |
| GSE20123 | APCDD1 | 147495 | 6 | 3 | 21 | |
| GSE43470 | APCDD1 | 147495 | 1 | 6 | 36 | |
| GSE46452 | APCDD1 | 147495 | 3 | 21 | 35 | |
| GSE47630 | APCDD1 | 147495 | 7 | 17 | 16 | |
| GSE54993 | APCDD1 | 147495 | 6 | 2 | 62 | |
| GSE54994 | APCDD1 | 147495 | 8 | 8 | 37 | |
| GSE60625 | APCDD1 | 147495 | 0 | 4 | 7 | |
| GSE74703 | APCDD1 | 147495 | 1 | 4 | 31 | |
| GSE74704 | APCDD1 | 147495 | 4 | 2 | 14 | |
| TCGA | APCDD1 | 147495 | 28 | 24 | 44 |
Total number of gains: 70; Total number of losses: 94; Total Number of normals: 324.
Somatic mutations of APCDD1:
Generating mutation plots.
Highly correlated genes for APCDD1:
Showing top 20/38 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APCDD1 | OPN3 | 0.634138 | 3 | 0 | 3 |
| APCDD1 | PEX6 | 0.617795 | 3 | 0 | 3 |
| APCDD1 | C10orf99 | 0.602439 | 4 | 0 | 3 |
| APCDD1 | ATP1B1 | 0.59808 | 4 | 0 | 3 |
| APCDD1 | SPTLC3 | 0.597849 | 5 | 0 | 4 |
| APCDD1 | TGM1 | 0.58679 | 4 | 0 | 3 |
| APCDD1 | SLC7A1 | 0.571129 | 5 | 0 | 4 |
| APCDD1 | ACADM | 0.565511 | 4 | 0 | 3 |
| APCDD1 | IL20RB | 0.563175 | 5 | 0 | 3 |
| APCDD1 | LYNX1 | 0.56122 | 4 | 0 | 3 |
| APCDD1 | CRABP2 | 0.560932 | 7 | 0 | 5 |
| APCDD1 | MFAP3 | 0.560729 | 3 | 0 | 3 |
| APCDD1 | LINC01159 | 0.553608 | 3 | 0 | 3 |
| APCDD1 | PAQR5 | 0.552464 | 4 | 0 | 3 |
| APCDD1 | SMAD6 | 0.550154 | 3 | 0 | 3 |
| APCDD1 | SFXN3 | 0.549093 | 4 | 0 | 4 |
| APCDD1 | HES1 | 0.547812 | 4 | 0 | 3 |
| APCDD1 | CWH43 | 0.547471 | 4 | 0 | 3 |
| APCDD1 | HSPA2 | 0.547124 | 8 | 0 | 4 |
| APCDD1 | LPAR6 | 0.545141 | 4 | 0 | 3 |
For details and further investigation, click here
