| Full name: potassium voltage-gated channel subfamily D member 2 | Alias Symbol: Kv4.2|RK5|KIAA1044 | ||
| Type: protein-coding gene | Cytoband: 7q31.31 | ||
| Entrez ID: 3751 | HGNC ID: HGNC:6238 | Ensembl Gene: ENSG00000184408 | OMIM ID: 605410 |
| Drug and gene relationship at DGIdb | |||
Expression of KCND2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCND2 | 3751 | 207103_at | 0.7892 | 0.2725 | |
| GSE20347 | KCND2 | 3751 | 207103_at | 0.3334 | 0.0001 | |
| GSE23400 | KCND2 | 3751 | 207103_at | 0.0522 | 0.0151 | |
| GSE26886 | KCND2 | 3751 | 207103_at | 0.4665 | 0.0037 | |
| GSE29001 | KCND2 | 3751 | 207103_at | 0.1309 | 0.3692 | |
| GSE38129 | KCND2 | 3751 | 207103_at | 0.3519 | 0.0004 | |
| GSE45670 | KCND2 | 3751 | 207103_at | 0.0083 | 0.9726 | |
| GSE53622 | KCND2 | 3751 | 6963 | 0.6823 | 0.0000 | |
| GSE53624 | KCND2 | 3751 | 6963 | 1.4241 | 0.0000 | |
| GSE63941 | KCND2 | 3751 | 207103_at | -4.5649 | 0.0000 | |
| GSE77861 | KCND2 | 3751 | 207103_at | 0.0787 | 0.4772 | |
| SRP007169 | KCND2 | 3751 | RNAseq | 4.7008 | 0.0001 | |
| SRP133303 | KCND2 | 3751 | RNAseq | 3.1619 | 0.0000 | |
| SRP159526 | KCND2 | 3751 | RNAseq | 2.1482 | 0.0002 | |
| SRP219564 | KCND2 | 3751 | RNAseq | 2.1207 | 0.0289 | |
| TCGA | KCND2 | 3751 | RNAseq | 0.9040 | 0.0027 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by KCND2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCND2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCND2 | 3751 | 7 | 2 | 21 | |
| GSE20123 | KCND2 | 3751 | 8 | 2 | 20 | |
| GSE43470 | KCND2 | 3751 | 3 | 3 | 37 | |
| GSE46452 | KCND2 | 3751 | 8 | 1 | 50 | |
| GSE47630 | KCND2 | 3751 | 7 | 4 | 29 | |
| GSE54993 | KCND2 | 3751 | 2 | 6 | 62 | |
| GSE54994 | KCND2 | 3751 | 11 | 5 | 37 | |
| GSE60625 | KCND2 | 3751 | 0 | 0 | 11 | |
| GSE74703 | KCND2 | 3751 | 3 | 3 | 30 | |
| GSE74704 | KCND2 | 3751 | 6 | 2 | 12 | |
| TCGA | KCND2 | 3751 | 31 | 18 | 47 |
Total number of gains: 86; Total number of losses: 46; Total Number of normals: 356.
Somatic mutations of KCND2:
Generating mutation plots.
Highly correlated genes for KCND2:
Showing top 20/420 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCND2 | CHSY3 | 0.745539 | 7 | 0 | 7 |
| KCND2 | GRM3 | 0.736152 | 3 | 0 | 3 |
| KCND2 | NID2 | 0.727194 | 8 | 0 | 8 |
| KCND2 | DACT1 | 0.717043 | 10 | 0 | 10 |
| KCND2 | OSR1 | 0.709164 | 3 | 0 | 3 |
| KCND2 | FAP | 0.703513 | 8 | 0 | 8 |
| KCND2 | CTSK | 0.702914 | 10 | 0 | 10 |
| KCND2 | POSTN | 0.691593 | 10 | 0 | 9 |
| KCND2 | VCAN | 0.687725 | 10 | 0 | 9 |
| KCND2 | PTX3 | 0.684972 | 3 | 0 | 3 |
| KCND2 | NOX4 | 0.68404 | 11 | 0 | 10 |
| KCND2 | CPT1C | 0.679771 | 3 | 0 | 3 |
| KCND2 | ADAMTS12 | 0.67833 | 7 | 0 | 6 |
| KCND2 | COL11A1 | 0.677907 | 11 | 0 | 9 |
| KCND2 | COL10A1 | 0.676194 | 9 | 0 | 9 |
| KCND2 | ZNF469 | 0.667365 | 7 | 0 | 6 |
| KCND2 | LRRC15 | 0.657569 | 10 | 0 | 8 |
| KCND2 | SULF1 | 0.657267 | 11 | 0 | 10 |
| KCND2 | FNDC1 | 0.65627 | 8 | 0 | 7 |
| KCND2 | THY1 | 0.653708 | 11 | 0 | 10 |
For details and further investigation, click here
