| Full name: progestin and adipoQ receptor family member 5 | Alias Symbol: FLJ20190|MPRG | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 54852 | HGNC ID: HGNC:29645 | Ensembl Gene: ENSG00000137819 | OMIM ID: 607781 |
| Drug and gene relationship at DGIdb | |||
Expression of PAQR5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAQR5 | 54852 | 242871_at | -1.4254 | 0.4486 | |
| GSE20347 | PAQR5 | 54852 | 220333_at | -0.4547 | 0.0023 | |
| GSE23400 | PAQR5 | 54852 | 220333_at | -0.2372 | 0.0000 | |
| GSE26886 | PAQR5 | 54852 | 242871_at | -1.7212 | 0.0082 | |
| GSE29001 | PAQR5 | 54852 | 220333_at | -0.7865 | 0.0027 | |
| GSE38129 | PAQR5 | 54852 | 220333_at | -0.3657 | 0.0139 | |
| GSE45670 | PAQR5 | 54852 | 242871_at | -1.0214 | 0.0179 | |
| GSE53622 | PAQR5 | 54852 | 83695 | -1.2685 | 0.0000 | |
| GSE53624 | PAQR5 | 54852 | 83695 | -1.6033 | 0.0000 | |
| GSE63941 | PAQR5 | 54852 | 242871_at | -1.8067 | 0.1412 | |
| GSE77861 | PAQR5 | 54852 | 242871_at | -1.9612 | 0.0032 | |
| SRP007169 | PAQR5 | 54852 | RNAseq | -3.6211 | 0.0000 | |
| SRP008496 | PAQR5 | 54852 | RNAseq | -2.8402 | 0.0000 | |
| SRP064894 | PAQR5 | 54852 | RNAseq | -1.0869 | 0.0029 | |
| SRP133303 | PAQR5 | 54852 | RNAseq | -1.2893 | 0.0000 | |
| SRP159526 | PAQR5 | 54852 | RNAseq | -2.1322 | 0.0002 | |
| SRP193095 | PAQR5 | 54852 | RNAseq | -1.5147 | 0.0000 | |
| SRP219564 | PAQR5 | 54852 | RNAseq | -1.3183 | 0.1579 | |
| TCGA | PAQR5 | 54852 | RNAseq | -0.4820 | 0.0197 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by PAQR5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAQR5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAQR5 | 54852 | 7 | 1 | 22 | |
| GSE20123 | PAQR5 | 54852 | 7 | 1 | 22 | |
| GSE43470 | PAQR5 | 54852 | 4 | 6 | 33 | |
| GSE46452 | PAQR5 | 54852 | 3 | 7 | 49 | |
| GSE47630 | PAQR5 | 54852 | 8 | 10 | 22 | |
| GSE54993 | PAQR5 | 54852 | 5 | 6 | 59 | |
| GSE54994 | PAQR5 | 54852 | 5 | 8 | 40 | |
| GSE60625 | PAQR5 | 54852 | 4 | 0 | 7 | |
| GSE74703 | PAQR5 | 54852 | 4 | 3 | 29 | |
| GSE74704 | PAQR5 | 54852 | 3 | 1 | 16 | |
| TCGA | PAQR5 | 54852 | 10 | 15 | 71 |
Total number of gains: 60; Total number of losses: 58; Total Number of normals: 370.
Somatic mutations of PAQR5:
Generating mutation plots.
Highly correlated genes for PAQR5:
Showing top 20/806 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAQR5 | CWH43 | 0.743246 | 10 | 0 | 10 |
| PAQR5 | ARF4 | 0.706376 | 3 | 0 | 3 |
| PAQR5 | KCNK7 | 0.696781 | 8 | 0 | 8 |
| PAQR5 | MXD1 | 0.695301 | 10 | 0 | 10 |
| PAQR5 | RDH12 | 0.68534 | 6 | 0 | 5 |
| PAQR5 | GRPEL2 | 0.684965 | 6 | 0 | 6 |
| PAQR5 | RAB10 | 0.678933 | 6 | 0 | 6 |
| PAQR5 | PRDM1 | 0.678608 | 10 | 0 | 10 |
| PAQR5 | KCNK6 | 0.677997 | 5 | 0 | 4 |
| PAQR5 | CRCT1 | 0.677025 | 11 | 0 | 10 |
| PAQR5 | TXNDC17 | 0.676834 | 3 | 0 | 3 |
| PAQR5 | CDA | 0.674575 | 11 | 0 | 10 |
| PAQR5 | TRAPPC13 | 0.673498 | 3 | 0 | 3 |
| PAQR5 | SPATA19 | 0.672842 | 3 | 0 | 3 |
| PAQR5 | ENDOU | 0.672435 | 10 | 0 | 9 |
| PAQR5 | GDPD3 | 0.671696 | 11 | 0 | 10 |
| PAQR5 | FCHO2 | 0.67125 | 5 | 0 | 5 |
| PAQR5 | SLC46A2 | 0.668926 | 6 | 0 | 5 |
| PAQR5 | ATP6V1D | 0.665029 | 10 | 0 | 9 |
| PAQR5 | SDR16C5 | 0.664352 | 5 | 0 | 4 |
For details and further investigation, click here
