| Full name: Purkinje cell protein 4 like 1 | Alias Symbol: IQM1 | ||
| Type: protein-coding gene | Cytoband: 1q23.3 | ||
| Entrez ID: 654790 | HGNC ID: HGNC:20448 | Ensembl Gene: ENSG00000248485 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PCP4L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCP4L1 | 654790 | 241382_at | -1.6984 | 0.0877 | |
| GSE26886 | PCP4L1 | 654790 | 241382_at | -1.6719 | 0.0004 | |
| GSE45670 | PCP4L1 | 654790 | 241382_at | 0.9994 | 0.0863 | |
| GSE53622 | PCP4L1 | 654790 | 105444 | -1.9391 | 0.0000 | |
| GSE53624 | PCP4L1 | 654790 | 105444 | -1.7273 | 0.0000 | |
| GSE63941 | PCP4L1 | 654790 | 241382_at | 0.3009 | 0.5110 | |
| GSE77861 | PCP4L1 | 654790 | 241382_at | -0.2305 | 0.6622 | |
| GSE97050 | PCP4L1 | 654790 | A_32_P214665 | -1.3798 | 0.2013 | |
| SRP007169 | PCP4L1 | 654790 | RNAseq | -0.8596 | 0.2735 | |
| SRP008496 | PCP4L1 | 654790 | RNAseq | -2.3990 | 0.0034 | |
| SRP064894 | PCP4L1 | 654790 | RNAseq | -1.6756 | 0.0001 | |
| SRP133303 | PCP4L1 | 654790 | RNAseq | -2.0554 | 0.0000 | |
| SRP159526 | PCP4L1 | 654790 | RNAseq | -1.8930 | 0.0000 | |
| SRP219564 | PCP4L1 | 654790 | RNAseq | -1.1982 | 0.2040 | |
| TCGA | PCP4L1 | 654790 | RNAseq | -0.0614 | 0.8739 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by PCP4L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCP4L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCP4L1 | 654790 | 10 | 0 | 20 | |
| GSE20123 | PCP4L1 | 654790 | 10 | 0 | 20 | |
| GSE43470 | PCP4L1 | 654790 | 7 | 2 | 34 | |
| GSE46452 | PCP4L1 | 654790 | 2 | 1 | 56 | |
| GSE47630 | PCP4L1 | 654790 | 14 | 0 | 26 | |
| GSE54993 | PCP4L1 | 654790 | 0 | 6 | 64 | |
| GSE54994 | PCP4L1 | 654790 | 16 | 0 | 37 | |
| GSE60625 | PCP4L1 | 654790 | 0 | 0 | 11 | |
| GSE74703 | PCP4L1 | 654790 | 7 | 2 | 27 | |
| GSE74704 | PCP4L1 | 654790 | 4 | 0 | 16 | |
| TCGA | PCP4L1 | 654790 | 44 | 3 | 49 |
Total number of gains: 114; Total number of losses: 14; Total Number of normals: 360.
Somatic mutations of PCP4L1:
Generating mutation plots.
Highly correlated genes for PCP4L1:
Showing top 20/459 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCP4L1 | SKP1 | 0.734285 | 3 | 0 | 3 |
| PCP4L1 | UBE2D2 | 0.713908 | 3 | 0 | 3 |
| PCP4L1 | PPP1R3C | 0.711117 | 5 | 0 | 5 |
| PCP4L1 | PPM1L | 0.693877 | 3 | 0 | 3 |
| PCP4L1 | ANKRD35 | 0.687328 | 5 | 0 | 5 |
| PCP4L1 | HIGD1A | 0.684088 | 5 | 0 | 4 |
| PCP4L1 | CLCA4 | 0.675636 | 4 | 0 | 4 |
| PCP4L1 | MAOA | 0.672605 | 5 | 0 | 4 |
| PCP4L1 | GAB1 | 0.671439 | 4 | 0 | 4 |
| PCP4L1 | PGM5 | 0.671137 | 3 | 0 | 3 |
| PCP4L1 | PTGS1 | 0.667554 | 4 | 0 | 3 |
| PCP4L1 | NFIX | 0.667516 | 3 | 0 | 3 |
| PCP4L1 | KLK13 | 0.667349 | 4 | 0 | 4 |
| PCP4L1 | SNX2 | 0.667212 | 4 | 0 | 3 |
| PCP4L1 | PLEKHA6 | 0.666314 | 4 | 0 | 4 |
| PCP4L1 | TBC1D20 | 0.666017 | 3 | 0 | 3 |
| PCP4L1 | RALGPS1 | 0.664602 | 3 | 0 | 3 |
| PCP4L1 | SYNGR1 | 0.661841 | 5 | 0 | 5 |
| PCP4L1 | GPD1L | 0.660604 | 5 | 0 | 4 |
| PCP4L1 | GTF3C6 | 0.659499 | 3 | 0 | 3 |
For details and further investigation, click here
