PDCD10

 

Full name: programmed cell death 10 Alias Symbol: TFAR15
Type: protein-coding gene Cytoband: 3q26.1
Entrez ID: 11235 HGNC ID: HGNC:8761 Ensembl Gene: ENSG00000114209 OMIM ID: 609118
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of PDCD10:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PDCD10 11235 210907_s_at 0.2798 0.3168
GSE20347 PDCD10 11235 210907_s_at 0.2621 0.0871
GSE23400 PDCD10 11235 210907_s_at 0.2966 0.0002
GSE26886 PDCD10 11235 210907_s_at 0.3219 0.0496
GSE29001 PDCD10 11235 210907_s_at 0.2171 0.7330
GSE38129 PDCD10 11235 210907_s_at 0.4507 0.0011
GSE45670 PDCD10 11235 210907_s_at 0.2582 0.1344
GSE53622 PDCD10 11235 64155 0.2135 0.0011
GSE53624 PDCD10 11235 64155 0.2450 0.0016
GSE63941 PDCD10 11235 210907_s_at 1.1307 0.0119
GSE77861 PDCD10 11235 210907_s_at -0.0375 0.9058
GSE97050 PDCD10 11235 A_23_P18325 0.4413 0.1772
SRP007169 PDCD10 11235 RNAseq -0.3399 0.2872
SRP008496 PDCD10 11235 RNAseq -0.1076 0.5934
SRP064894 PDCD10 11235 RNAseq 0.0058 0.9792
SRP133303 PDCD10 11235 RNAseq 0.6679 0.0003
SRP159526 PDCD10 11235 RNAseq 0.3790 0.3868
SRP193095 PDCD10 11235 RNAseq 0.0769 0.6201
SRP219564 PDCD10 11235 RNAseq -0.3819 0.4340
TCGA PDCD10 11235 RNAseq 0.2353 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by PDCD10 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PDCD10:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PDCD10 11235 22 0 8
GSE20123 PDCD10 11235 22 0 8
GSE43470 PDCD10 11235 23 0 20
GSE46452 PDCD10 11235 19 1 39
GSE47630 PDCD10 11235 27 2 11
GSE54993 PDCD10 11235 1 13 56
GSE54994 PDCD10 11235 41 0 12
GSE60625 PDCD10 11235 0 6 5
GSE74703 PDCD10 11235 19 0 17
GSE74704 PDCD10 11235 14 0 6
TCGA PDCD10 11235 79 0 17

Total number of gains: 267; Total number of losses: 22; Total Number of normals: 199.  

 

Somatic mutations of PDCD10:

 

Generating mutation plots.

 

Highly correlated genes for PDCD10:

 

Showing top 20/757 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PDCD10PSPC10.717805303
PDCD10PHF140.673955504
PDCD10SRSF90.671439303
PDCD10TIMMDC10.67122303
PDCD10RCC20.669149404
PDCD10COPB20.6656441209
PDCD10RPAP30.665222807
PDCD10CALML50.665025303
PDCD10NMD30.66394113013
PDCD10FAM110A0.663512303
PDCD10NDUFB50.663245907
PDCD10UTP200.659414303
PDCD10ATG30.6592831108
PDCD10CHML0.658353303
PDCD10CCNE10.655871403
PDCD10TXNDC90.6557991008
PDCD10ABCF30.655711806
PDCD10CNOT100.65552303
PDCD10RASA20.654328403
PDCD10SIX40.654307404

For details and further investigation, click here