| Full name: proteolipid protein 2 | Alias Symbol: A4|A4-LSB|MGC126187 | ||
| Type: protein-coding gene | Cytoband: Xp11.23 | ||
| Entrez ID: 5355 | HGNC ID: HGNC:9087 | Ensembl Gene: ENSG00000102007 | OMIM ID: 300112 |
| Drug and gene relationship at DGIdb | |||
Expression of PLP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLP2 | 5355 | 201136_at | -0.1608 | 0.5552 | |
| GSE20347 | PLP2 | 5355 | 201136_at | -0.4545 | 0.0239 | |
| GSE23400 | PLP2 | 5355 | 201136_at | -0.1348 | 0.1595 | |
| GSE26886 | PLP2 | 5355 | 201136_at | -0.8239 | 0.0003 | |
| GSE29001 | PLP2 | 5355 | 201136_at | -0.5403 | 0.2102 | |
| GSE38129 | PLP2 | 5355 | 201136_at | -0.0345 | 0.8994 | |
| GSE45670 | PLP2 | 5355 | 201136_at | 0.0188 | 0.9421 | |
| GSE53622 | PLP2 | 5355 | 137986 | -0.4033 | 0.0001 | |
| GSE53624 | PLP2 | 5355 | 137986 | -0.2162 | 0.0009 | |
| GSE63941 | PLP2 | 5355 | 201136_at | 1.4482 | 0.0037 | |
| GSE77861 | PLP2 | 5355 | 201136_at | -0.1914 | 0.4741 | |
| GSE97050 | PLP2 | 5355 | A_24_P74932 | -0.0149 | 0.9774 | |
| SRP007169 | PLP2 | 5355 | RNAseq | -0.9651 | 0.0350 | |
| SRP008496 | PLP2 | 5355 | RNAseq | -1.0135 | 0.0000 | |
| SRP064894 | PLP2 | 5355 | RNAseq | 0.2423 | 0.4325 | |
| SRP133303 | PLP2 | 5355 | RNAseq | 0.1192 | 0.6915 | |
| SRP159526 | PLP2 | 5355 | RNAseq | -0.4387 | 0.1976 | |
| SRP193095 | PLP2 | 5355 | RNAseq | -0.3587 | 0.0964 | |
| SRP219564 | PLP2 | 5355 | RNAseq | -0.0193 | 0.9686 | |
| TCGA | PLP2 | 5355 | RNAseq | 0.2929 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by PLP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLP2:
No record found for this gene.
Somatic mutations of PLP2:
Generating mutation plots.
Highly correlated genes for PLP2:
Showing top 20/340 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLP2 | ARFGAP2 | 0.69122 | 4 | 0 | 4 |
| PLP2 | PAOX | 0.674489 | 3 | 0 | 3 |
| PLP2 | RPUSD1 | 0.667674 | 3 | 0 | 3 |
| PLP2 | NDUFS3 | 0.667047 | 4 | 0 | 4 |
| PLP2 | FAR1 | 0.660858 | 3 | 0 | 3 |
| PLP2 | CXCL17 | 0.660251 | 4 | 0 | 3 |
| PLP2 | TSPAN14 | 0.658239 | 4 | 0 | 4 |
| PLP2 | TBC1D22B | 0.655514 | 3 | 0 | 3 |
| PLP2 | TMEM125 | 0.652838 | 3 | 0 | 3 |
| PLP2 | MACC1 | 0.645407 | 3 | 0 | 3 |
| PLP2 | PSMD6 | 0.6445 | 4 | 0 | 3 |
| PLP2 | POLR2L | 0.638283 | 4 | 0 | 4 |
| PLP2 | EIF2B1 | 0.634998 | 3 | 0 | 3 |
| PLP2 | CCNG2 | 0.633032 | 3 | 0 | 3 |
| PLP2 | RAET1E | 0.63126 | 3 | 0 | 3 |
| PLP2 | PGD | 0.618377 | 6 | 0 | 6 |
| PLP2 | KRT78 | 0.617286 | 3 | 0 | 3 |
| PLP2 | EIF4B | 0.61415 | 3 | 0 | 3 |
| PLP2 | ATP6V1F | 0.612123 | 10 | 0 | 7 |
| PLP2 | LANCL3 | 0.609791 | 3 | 0 | 3 |
For details and further investigation, click here
