| Full name: proteasome inhibitor subunit 1 | Alias Symbol: PI31 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 9491 | HGNC ID: HGNC:9571 | Ensembl Gene: ENSG00000125818 | OMIM ID: 617858 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PSMF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMF1 | 9491 | 201052_s_at | -0.0231 | 0.9766 | |
| GSE20347 | PSMF1 | 9491 | 201053_s_at | 0.2452 | 0.1217 | |
| GSE23400 | PSMF1 | 9491 | 201052_s_at | 0.1829 | 0.0219 | |
| GSE26886 | PSMF1 | 9491 | 201053_s_at | 1.1406 | 0.0000 | |
| GSE29001 | PSMF1 | 9491 | 201053_s_at | 0.5761 | 0.1064 | |
| GSE38129 | PSMF1 | 9491 | 201053_s_at | 0.1998 | 0.1613 | |
| GSE45670 | PSMF1 | 9491 | 201053_s_at | 0.1085 | 0.6601 | |
| GSE53622 | PSMF1 | 9491 | 9409 | 0.4423 | 0.0000 | |
| GSE53624 | PSMF1 | 9491 | 9409 | 0.4357 | 0.0000 | |
| GSE63941 | PSMF1 | 9491 | 201053_s_at | -0.4324 | 0.2447 | |
| GSE77861 | PSMF1 | 9491 | 201052_s_at | 0.0849 | 0.8101 | |
| GSE97050 | PSMF1 | 9491 | A_33_P3229722 | 0.6780 | 0.1616 | |
| SRP007169 | PSMF1 | 9491 | RNAseq | -0.4114 | 0.2266 | |
| SRP008496 | PSMF1 | 9491 | RNAseq | -0.2913 | 0.0896 | |
| SRP064894 | PSMF1 | 9491 | RNAseq | 0.2917 | 0.0714 | |
| SRP133303 | PSMF1 | 9491 | RNAseq | 0.1516 | 0.1474 | |
| SRP159526 | PSMF1 | 9491 | RNAseq | 0.1788 | 0.4132 | |
| SRP193095 | PSMF1 | 9491 | RNAseq | 0.0998 | 0.3419 | |
| SRP219564 | PSMF1 | 9491 | RNAseq | 0.2835 | 0.3422 | |
| TCGA | PSMF1 | 9491 | RNAseq | 0.0303 | 0.4927 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PSMF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMF1 | 9491 | 12 | 4 | 14 | |
| GSE20123 | PSMF1 | 9491 | 13 | 4 | 13 | |
| GSE43470 | PSMF1 | 9491 | 11 | 1 | 31 | |
| GSE46452 | PSMF1 | 9491 | 26 | 1 | 32 | |
| GSE47630 | PSMF1 | 9491 | 19 | 4 | 17 | |
| GSE54993 | PSMF1 | 9491 | 2 | 14 | 54 | |
| GSE54994 | PSMF1 | 9491 | 24 | 2 | 27 | |
| GSE60625 | PSMF1 | 9491 | 0 | 0 | 11 | |
| GSE74703 | PSMF1 | 9491 | 10 | 1 | 25 | |
| GSE74704 | PSMF1 | 9491 | 8 | 2 | 10 | |
| TCGA | PSMF1 | 9491 | 41 | 11 | 44 |
Total number of gains: 166; Total number of losses: 44; Total Number of normals: 278.
Somatic mutations of PSMF1:
Generating mutation plots.
Highly correlated genes for PSMF1:
Showing top 20/295 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMF1 | NOP56 | 0.745356 | 3 | 0 | 3 |
| PSMF1 | FAM160A2 | 0.697184 | 3 | 0 | 3 |
| PSMF1 | LSM10 | 0.638871 | 3 | 0 | 3 |
| PSMF1 | CHSY3 | 0.633279 | 4 | 0 | 3 |
| PSMF1 | EIF1B | 0.631553 | 3 | 0 | 3 |
| PSMF1 | CMSS1 | 0.630991 | 3 | 0 | 3 |
| PSMF1 | PDE4A | 0.630487 | 4 | 0 | 3 |
| PSMF1 | PTPRK | 0.623118 | 5 | 0 | 4 |
| PSMF1 | PLCG1 | 0.622335 | 5 | 0 | 4 |
| PSMF1 | CSNK2A1 | 0.621401 | 9 | 0 | 8 |
| PSMF1 | EXT1 | 0.620431 | 6 | 0 | 5 |
| PSMF1 | FMNL2 | 0.615808 | 4 | 0 | 4 |
| PSMF1 | PHTF2 | 0.615208 | 3 | 0 | 3 |
| PSMF1 | MICALL2 | 0.613207 | 3 | 0 | 3 |
| PSMF1 | UBE2E3 | 0.612623 | 5 | 0 | 4 |
| PSMF1 | KTN1 | 0.612307 | 6 | 0 | 4 |
| PSMF1 | PRKDC | 0.612145 | 5 | 0 | 5 |
| PSMF1 | IFT43 | 0.609991 | 5 | 0 | 4 |
| PSMF1 | LAGE3 | 0.606517 | 4 | 0 | 3 |
| PSMF1 | DDRGK1 | 0.602654 | 11 | 0 | 8 |
For details and further investigation, click here
