| Full name: retinol binding protein 7 | Alias Symbol: CRBPIV | ||
| Type: protein-coding gene | Cytoband: 1p36.22 | ||
| Entrez ID: 116362 | HGNC ID: HGNC:30316 | Ensembl Gene: ENSG00000162444 | OMIM ID: 608604 |
| Drug and gene relationship at DGIdb | |||
Expression of RBP7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBP7 | 116362 | 238066_at | -1.9282 | 0.0171 | |
| GSE26886 | RBP7 | 116362 | 238066_at | -1.4419 | 0.0060 | |
| GSE45670 | RBP7 | 116362 | 238066_at | -1.4124 | 0.0013 | |
| GSE53622 | RBP7 | 116362 | 82218 | -2.2054 | 0.0000 | |
| GSE53624 | RBP7 | 116362 | 82218 | -2.0712 | 0.0000 | |
| GSE63941 | RBP7 | 116362 | 238066_at | 1.3490 | 0.3329 | |
| GSE77861 | RBP7 | 116362 | 238066_at | -1.4418 | 0.0116 | |
| GSE97050 | RBP7 | 116362 | A_24_P165423 | -0.7140 | 0.3237 | |
| SRP007169 | RBP7 | 116362 | RNAseq | -3.0002 | 0.0000 | |
| SRP008496 | RBP7 | 116362 | RNAseq | -2.4907 | 0.0000 | |
| SRP064894 | RBP7 | 116362 | RNAseq | -1.1272 | 0.0135 | |
| SRP133303 | RBP7 | 116362 | RNAseq | -2.2672 | 0.0000 | |
| SRP159526 | RBP7 | 116362 | RNAseq | -0.4846 | 0.3975 | |
| SRP219564 | RBP7 | 116362 | RNAseq | -2.0549 | 0.0026 | |
| TCGA | RBP7 | 116362 | RNAseq | -0.3720 | 0.1324 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by RBP7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBP7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBP7 | 116362 | 0 | 5 | 25 | |
| GSE20123 | RBP7 | 116362 | 0 | 3 | 27 | |
| GSE43470 | RBP7 | 116362 | 6 | 5 | 32 | |
| GSE46452 | RBP7 | 116362 | 7 | 1 | 51 | |
| GSE47630 | RBP7 | 116362 | 8 | 4 | 28 | |
| GSE54993 | RBP7 | 116362 | 3 | 1 | 66 | |
| GSE54994 | RBP7 | 116362 | 12 | 4 | 37 | |
| GSE60625 | RBP7 | 116362 | 0 | 0 | 11 | |
| GSE74703 | RBP7 | 116362 | 5 | 3 | 28 | |
| GSE74704 | RBP7 | 116362 | 0 | 0 | 20 | |
| TCGA | RBP7 | 116362 | 10 | 24 | 62 |
Total number of gains: 51; Total number of losses: 50; Total Number of normals: 387.
Somatic mutations of RBP7:
Generating mutation plots.
Highly correlated genes for RBP7:
Showing top 20/1025 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBP7 | SHROOM3 | 0.779139 | 7 | 0 | 7 |
| RBP7 | TCP11L2 | 0.764481 | 4 | 0 | 4 |
| RBP7 | CTTNBP2 | 0.763332 | 7 | 0 | 7 |
| RBP7 | FNDC4 | 0.75782 | 7 | 0 | 6 |
| RBP7 | MGST2 | 0.756464 | 6 | 0 | 6 |
| RBP7 | GYS2 | 0.756283 | 6 | 0 | 6 |
| RBP7 | BLOC1S1 | 0.750883 | 5 | 0 | 5 |
| RBP7 | SH3BGRL2 | 0.750027 | 7 | 0 | 7 |
| RBP7 | PAQR8 | 0.74411 | 6 | 0 | 6 |
| RBP7 | CPNE3 | 0.743562 | 5 | 0 | 5 |
| RBP7 | SORT1 | 0.743479 | 6 | 0 | 6 |
| RBP7 | PHACTR4 | 0.74025 | 6 | 0 | 6 |
| RBP7 | EPB41L3 | 0.736704 | 6 | 0 | 6 |
| RBP7 | USP54 | 0.734333 | 6 | 0 | 6 |
| RBP7 | FAM3D | 0.732138 | 6 | 0 | 6 |
| RBP7 | UBL3 | 0.732083 | 7 | 0 | 7 |
| RBP7 | CAPN5 | 0.731001 | 7 | 0 | 7 |
| RBP7 | HCG22 | 0.726855 | 6 | 0 | 6 |
| RBP7 | SPATA19 | 0.724419 | 3 | 0 | 3 |
| RBP7 | CRISP3 | 0.722856 | 6 | 0 | 6 |
For details and further investigation, click here
