| Full name: regulating synaptic membrane exocytosis 1 | Alias Symbol: RIM|KIAA0340|RIM1 | ||
| Type: protein-coding gene | Cytoband: 6q13 | ||
| Entrez ID: 22999 | HGNC ID: HGNC:17282 | Ensembl Gene: ENSG00000079841 | OMIM ID: 606629 |
| Drug and gene relationship at DGIdb | |||
Expression of RIMS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RIMS1 | 22999 | 231986_at | -0.8600 | 0.5107 | |
| GSE20347 | RIMS1 | 22999 | 216184_s_at | -0.1463 | 0.0887 | |
| GSE23400 | RIMS1 | 22999 | 216184_s_at | -0.2846 | 0.0000 | |
| GSE26886 | RIMS1 | 22999 | 216184_s_at | -0.1116 | 0.2776 | |
| GSE29001 | RIMS1 | 22999 | 216184_s_at | -0.2828 | 0.0030 | |
| GSE38129 | RIMS1 | 22999 | 216184_s_at | -0.1989 | 0.0155 | |
| GSE45670 | RIMS1 | 22999 | 231986_at | -0.3732 | 0.0075 | |
| GSE53622 | RIMS1 | 22999 | 122076 | -1.5487 | 0.0000 | |
| GSE53624 | RIMS1 | 22999 | 22738 | -2.2449 | 0.0000 | |
| GSE63941 | RIMS1 | 22999 | 231986_at | -0.7674 | 0.0003 | |
| GSE77861 | RIMS1 | 22999 | 216184_s_at | -0.2923 | 0.0888 | |
| SRP133303 | RIMS1 | 22999 | RNAseq | -1.3900 | 0.0375 | |
| SRP159526 | RIMS1 | 22999 | RNAseq | -0.7952 | 0.3618 | |
| SRP219564 | RIMS1 | 22999 | RNAseq | -1.7298 | 0.2587 | |
| TCGA | RIMS1 | 22999 | RNAseq | -1.2143 | 0.0640 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RIMS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RIMS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RIMS1 | 22999 | 1 | 3 | 26 | |
| GSE20123 | RIMS1 | 22999 | 1 | 2 | 27 | |
| GSE43470 | RIMS1 | 22999 | 3 | 0 | 40 | |
| GSE46452 | RIMS1 | 22999 | 2 | 11 | 46 | |
| GSE47630 | RIMS1 | 22999 | 8 | 4 | 28 | |
| GSE54993 | RIMS1 | 22999 | 3 | 2 | 65 | |
| GSE54994 | RIMS1 | 22999 | 9 | 5 | 39 | |
| GSE60625 | RIMS1 | 22999 | 0 | 1 | 10 | |
| GSE74703 | RIMS1 | 22999 | 3 | 0 | 33 | |
| GSE74704 | RIMS1 | 22999 | 0 | 1 | 19 | |
| TCGA | RIMS1 | 22999 | 9 | 21 | 66 |
Total number of gains: 39; Total number of losses: 50; Total Number of normals: 399.
Somatic mutations of RIMS1:
Generating mutation plots.
Highly correlated genes for RIMS1:
Showing top 20/712 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RIMS1 | SHISA3 | 0.72257 | 5 | 0 | 5 |
| RIMS1 | NEGR1 | 0.70805 | 5 | 0 | 5 |
| RIMS1 | LINC00702 | 0.693757 | 3 | 0 | 3 |
| RIMS1 | RSPO2 | 0.688956 | 3 | 0 | 3 |
| RIMS1 | CADM2 | 0.685796 | 3 | 0 | 3 |
| RIMS1 | ASB5 | 0.681758 | 5 | 0 | 5 |
| RIMS1 | NEXN | 0.681282 | 5 | 0 | 5 |
| RIMS1 | FGA | 0.675555 | 4 | 0 | 3 |
| RIMS1 | CPA1 | 0.672871 | 4 | 0 | 4 |
| RIMS1 | BFSP2 | 0.672689 | 4 | 0 | 4 |
| RIMS1 | MRVI1 | 0.670089 | 5 | 0 | 4 |
| RIMS1 | GJB4 | 0.668216 | 4 | 0 | 4 |
| RIMS1 | PGR | 0.666793 | 6 | 0 | 5 |
| RIMS1 | MYO15A | 0.665626 | 4 | 0 | 3 |
| RIMS1 | MYOCD | 0.661889 | 5 | 0 | 5 |
| RIMS1 | TGM6 | 0.660738 | 3 | 0 | 3 |
| RIMS1 | ITGA1 | 0.658206 | 4 | 0 | 4 |
| RIMS1 | RBPMS2 | 0.657276 | 4 | 0 | 3 |
| RIMS1 | CYP2A6 | 0.656206 | 6 | 0 | 6 |
| RIMS1 | FENDRR | 0.654548 | 6 | 0 | 5 |
For details and further investigation, click here
