| Full name: suppressor of tumorigenicity 20 | Alias Symbol: HCCS-1 | ||
| Type: protein-coding gene | Cytoband: 15q25.1 | ||
| Entrez ID: 400410 | HGNC ID: HGNC:33520 | Ensembl Gene: | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ST20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST20 | 400410 | 210242_x_at | 0.3787 | 0.1529 | |
| GSE20347 | ST20 | 400410 | 210242_x_at | 0.1720 | 0.0931 | |
| GSE23400 | ST20 | 400410 | 210242_x_at | 0.1593 | 0.0000 | |
| GSE26886 | ST20 | 400410 | 210242_x_at | 0.7365 | 0.0001 | |
| GSE29001 | ST20 | 400410 | 210242_x_at | 0.1787 | 0.1335 | |
| GSE38129 | ST20 | 400410 | 210242_x_at | 0.4625 | 0.0001 | |
| GSE45670 | ST20 | 400410 | 210242_x_at | 0.3151 | 0.0021 | |
| GSE53622 | ST20 | 400410 | 37733 | 1.4757 | 0.0000 | |
| GSE53624 | ST20 | 400410 | 37733 | 1.2778 | 0.0000 | |
| GSE63941 | ST20 | 400410 | 210242_x_at | -0.4461 | 0.2544 | |
| GSE77861 | ST20 | 400410 | 210242_x_at | 0.1138 | 0.4997 | |
| SRP064894 | ST20 | 400410 | RNAseq | 0.8977 | 0.0155 | |
| SRP133303 | ST20 | 400410 | RNAseq | 0.7778 | 0.0057 | |
| SRP159526 | ST20 | 400410 | RNAseq | 1.0975 | 0.0191 | |
| SRP193095 | ST20 | 400410 | RNAseq | 0.6475 | 0.0000 | |
| SRP219564 | ST20 | 400410 | RNAseq | 0.7021 | 0.0608 | |
| TCGA | ST20 | 400410 | RNAseq | 0.6513 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ST20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST20 | 400410 | 7 | 1 | 22 | |
| GSE20123 | ST20 | 400410 | 7 | 1 | 22 | |
| GSE43470 | ST20 | 400410 | 4 | 4 | 35 | |
| GSE46452 | ST20 | 400410 | 3 | 7 | 49 | |
| GSE47630 | ST20 | 400410 | 8 | 10 | 22 | |
| GSE54993 | ST20 | 400410 | 5 | 6 | 59 | |
| GSE54994 | ST20 | 400410 | 5 | 6 | 42 | |
| GSE60625 | ST20 | 400410 | 4 | 0 | 7 | |
| GSE74703 | ST20 | 400410 | 4 | 2 | 30 | |
| GSE74704 | ST20 | 400410 | 3 | 1 | 16 | |
| TCGA | ST20 | 400410 | 14 | 15 | 67 |
Total number of gains: 64; Total number of losses: 53; Total Number of normals: 371.
Somatic mutations of ST20:
Generating mutation plots.
Highly correlated genes for ST20:
Showing top 20/1013 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST20 | IL4I1 | 0.788206 | 3 | 0 | 3 |
| ST20 | APOC1 | 0.722039 | 3 | 0 | 3 |
| ST20 | WDR54 | 0.706383 | 5 | 0 | 5 |
| ST20 | RNF168 | 0.700216 | 4 | 0 | 4 |
| ST20 | NTMT1 | 0.698235 | 5 | 0 | 5 |
| ST20 | SOX11 | 0.694041 | 4 | 0 | 4 |
| ST20 | CEP78 | 0.692037 | 5 | 0 | 5 |
| ST20 | TTYH3 | 0.688092 | 5 | 0 | 5 |
| ST20 | KNSTRN | 0.680772 | 6 | 0 | 5 |
| ST20 | CABLES2 | 0.675665 | 4 | 0 | 3 |
| ST20 | STC2 | 0.672807 | 6 | 0 | 6 |
| ST20 | MRPL21 | 0.666069 | 4 | 0 | 3 |
| ST20 | SDS | 0.664179 | 3 | 0 | 3 |
| ST20 | ZIC5 | 0.659556 | 3 | 0 | 3 |
| ST20 | PGP | 0.655715 | 4 | 0 | 3 |
| ST20 | CENPL | 0.654913 | 5 | 0 | 5 |
| ST20 | CTHRC1 | 0.654109 | 6 | 0 | 5 |
| ST20 | DDX54 | 0.653854 | 4 | 0 | 4 |
| ST20 | LCLAT1 | 0.653217 | 5 | 0 | 5 |
| ST20 | UBE2T | 0.652649 | 6 | 0 | 5 |
For details and further investigation, click here
