| Full name: glycerol kinase | Alias Symbol: GK1|GKD | ||
| Type: protein-coding gene | Cytoband: Xp21.2 | ||
| Entrez ID: 2710 | HGNC ID: HGNC:4289 | Ensembl Gene: ENSG00000198814 | OMIM ID: 300474 |
| Drug and gene relationship at DGIdb | |||
GK involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03320 | PPAR signaling pathway |
Expression of GK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GK | 2710 | 217167_x_at | -0.0021 | 0.9985 | |
| GSE20347 | GK | 2710 | 214681_at | -0.3232 | 0.0222 | |
| GSE26886 | GK | 2710 | 217167_x_at | -0.5735 | 0.0025 | |
| GSE29001 | GK | 2710 | 217167_x_at | -0.2327 | 0.0936 | |
| GSE38129 | GK | 2710 | 214681_at | -0.2380 | 0.0915 | |
| GSE45670 | GK | 2710 | 215977_x_at | 0.4883 | 0.0153 | |
| GSE53622 | GK | 2710 | 16383 | 0.9209 | 0.0001 | |
| GSE53624 | GK | 2710 | 16383 | 0.3019 | 0.0087 | |
| GSE63941 | GK | 2710 | 217167_x_at | -1.3833 | 0.0156 | |
| GSE77861 | GK | 2710 | 215977_x_at | -0.2151 | 0.3555 | |
| GSE97050 | GK | 2710 | A_32_P172848 | 0.8186 | 0.1791 | |
| SRP007169 | GK | 2710 | RNAseq | -0.7714 | 0.0195 | |
| SRP008496 | GK | 2710 | RNAseq | -1.1154 | 0.0000 | |
| SRP064894 | GK | 2710 | RNAseq | 0.4388 | 0.1900 | |
| SRP133303 | GK | 2710 | RNAseq | 0.8864 | 0.0002 | |
| SRP159526 | GK | 2710 | RNAseq | -0.5972 | 0.1223 | |
| SRP193095 | GK | 2710 | RNAseq | -0.1214 | 0.5786 | |
| SRP219564 | GK | 2710 | RNAseq | 0.6731 | 0.2615 | |
| TCGA | GK | 2710 | RNAseq | 0.2031 | 0.0866 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GK:
No record found for this gene.
Somatic mutations of GK:
Generating mutation plots.
Highly correlated genes for GK:
Showing top 20/278 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GK | TTC39C | 0.786077 | 3 | 0 | 3 |
| GK | LZTS1 | 0.734206 | 3 | 0 | 3 |
| GK | APBB1IP | 0.730645 | 3 | 0 | 3 |
| GK | RNF183 | 0.724096 | 3 | 0 | 3 |
| GK | CPA2 | 0.705523 | 3 | 0 | 3 |
| GK | CD79B | 0.702447 | 4 | 0 | 3 |
| GK | IKZF3 | 0.698782 | 3 | 0 | 3 |
| GK | CCR2 | 0.693427 | 4 | 0 | 4 |
| GK | SERPINA1 | 0.691273 | 3 | 0 | 3 |
| GK | IL10RB | 0.675825 | 5 | 0 | 4 |
| GK | P2RY13 | 0.672905 | 4 | 0 | 4 |
| GK | CXCR6 | 0.671871 | 4 | 0 | 4 |
| GK | SEC61B | 0.667019 | 4 | 0 | 3 |
| GK | BCL2L1 | 0.666395 | 3 | 0 | 3 |
| GK | CD79A | 0.664902 | 3 | 0 | 3 |
| GK | IRF4 | 0.664815 | 4 | 0 | 3 |
| GK | GABRR2 | 0.662147 | 3 | 0 | 3 |
| GK | OSBPL8 | 0.658471 | 3 | 0 | 3 |
| GK | IL1R1 | 0.656093 | 4 | 0 | 3 |
| GK | CYP7B1 | 0.654692 | 4 | 0 | 4 |
For details and further investigation, click here
