| Full name: arginyl aminopeptidase | Alias Symbol: APB | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 6051 | HGNC ID: HGNC:10078 | Ensembl Gene: ENSG00000176393 | OMIM ID: 602675 |
| Drug and gene relationship at DGIdb | |||
Expression of RNPEP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNPEP | 6051 | 208270_s_at | -0.0956 | 0.8664 | |
| GSE20347 | RNPEP | 6051 | 208270_s_at | -0.7115 | 0.0000 | |
| GSE23400 | RNPEP | 6051 | 208270_s_at | -0.2339 | 0.0063 | |
| GSE26886 | RNPEP | 6051 | 208270_s_at | -0.7574 | 0.0025 | |
| GSE29001 | RNPEP | 6051 | 208270_s_at | -0.7908 | 0.0466 | |
| GSE38129 | RNPEP | 6051 | 208270_s_at | -0.2214 | 0.2706 | |
| GSE45670 | RNPEP | 6051 | 208270_s_at | -0.1945 | 0.1692 | |
| GSE63941 | RNPEP | 6051 | 208270_s_at | 0.4035 | 0.3284 | |
| GSE77861 | RNPEP | 6051 | 208270_s_at | -0.2183 | 0.3735 | |
| GSE97050 | RNPEP | 6051 | A_33_P3258091 | 0.0471 | 0.9023 | |
| SRP007169 | RNPEP | 6051 | RNAseq | -1.8096 | 0.0000 | |
| SRP008496 | RNPEP | 6051 | RNAseq | -1.8204 | 0.0000 | |
| SRP064894 | RNPEP | 6051 | RNAseq | -0.1120 | 0.5035 | |
| SRP133303 | RNPEP | 6051 | RNAseq | -0.3139 | 0.0458 | |
| SRP159526 | RNPEP | 6051 | RNAseq | 0.0002 | 0.9994 | |
| SRP193095 | RNPEP | 6051 | RNAseq | -0.5246 | 0.0000 | |
| SRP219564 | RNPEP | 6051 | RNAseq | -0.1094 | 0.7930 | |
| TCGA | RNPEP | 6051 | RNAseq | 0.1377 | 0.0062 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RNPEP expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RNPEP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNPEP | 6051 | 11 | 0 | 19 | |
| GSE20123 | RNPEP | 6051 | 11 | 0 | 19 | |
| GSE43470 | RNPEP | 6051 | 6 | 0 | 37 | |
| GSE46452 | RNPEP | 6051 | 3 | 1 | 55 | |
| GSE47630 | RNPEP | 6051 | 14 | 0 | 26 | |
| GSE54993 | RNPEP | 6051 | 0 | 6 | 64 | |
| GSE54994 | RNPEP | 6051 | 15 | 0 | 38 | |
| GSE60625 | RNPEP | 6051 | 0 | 0 | 11 | |
| GSE74703 | RNPEP | 6051 | 6 | 0 | 30 | |
| GSE74704 | RNPEP | 6051 | 5 | 0 | 15 | |
| TCGA | RNPEP | 6051 | 43 | 4 | 49 |
Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.
Somatic mutations of RNPEP:
Generating mutation plots.
Highly correlated genes for RNPEP:
Showing top 20/723 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNPEP | PARD6G | 0.714492 | 3 | 0 | 3 |
| RNPEP | C15orf48 | 0.693569 | 4 | 0 | 3 |
| RNPEP | GLUD1 | 0.692029 | 3 | 0 | 3 |
| RNPEP | CCNYL1 | 0.681216 | 3 | 0 | 3 |
| RNPEP | DHCR24 | 0.67785 | 8 | 0 | 8 |
| RNPEP | GRHL1 | 0.675913 | 4 | 0 | 4 |
| RNPEP | PWWP2B | 0.675038 | 3 | 0 | 3 |
| RNPEP | TMED3 | 0.674634 | 9 | 0 | 8 |
| RNPEP | VAMP8 | 0.673963 | 9 | 0 | 7 |
| RNPEP | GJB5 | 0.666281 | 7 | 0 | 7 |
| RNPEP | FBXL5 | 0.665722 | 4 | 0 | 4 |
| RNPEP | KRT15 | 0.664017 | 5 | 0 | 4 |
| RNPEP | GIPC1 | 0.661999 | 7 | 0 | 6 |
| RNPEP | APEH | 0.661972 | 6 | 0 | 4 |
| RNPEP | CD59 | 0.661703 | 4 | 0 | 4 |
| RNPEP | GRN | 0.660905 | 8 | 0 | 7 |
| RNPEP | TMEM79 | 0.660494 | 4 | 0 | 4 |
| RNPEP | P4HB | 0.660109 | 8 | 0 | 8 |
| RNPEP | TRIM29 | 0.657041 | 9 | 0 | 8 |
| RNPEP | IRX5 | 0.656048 | 5 | 0 | 4 |
For details and further investigation, click here
