| Full name: UL16 binding protein 2 | Alias Symbol: RAET1H | ||
| Type: protein-coding gene | Cytoband: 6q25.1 | ||
| Entrez ID: 80328 | HGNC ID: HGNC:14894 | Ensembl Gene: ENSG00000131015 | OMIM ID: 605698 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
ULBP2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04650 | Natural killer cell mediated cytotoxicity |
Expression of ULBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ULBP2 | 80328 | 238542_at | 0.2461 | 0.8823 | |
| GSE20347 | ULBP2 | 80328 | 221291_at | -0.8702 | 0.0000 | |
| GSE23400 | ULBP2 | 80328 | 221291_at | -0.4956 | 0.0000 | |
| GSE26886 | ULBP2 | 80328 | 238542_at | -0.5769 | 0.0910 | |
| GSE29001 | ULBP2 | 80328 | 221291_at | -0.4611 | 0.0560 | |
| GSE38129 | ULBP2 | 80328 | 221291_at | -0.3917 | 0.1394 | |
| GSE45670 | ULBP2 | 80328 | 238542_at | 0.5294 | 0.0739 | |
| GSE53622 | ULBP2 | 80328 | 15107 | -0.3961 | 0.1083 | |
| GSE53624 | ULBP2 | 80328 | 15107 | -0.9874 | 0.0000 | |
| GSE63941 | ULBP2 | 80328 | 238542_at | 1.1878 | 0.1624 | |
| GSE77861 | ULBP2 | 80328 | 238542_at | 0.3396 | 0.3773 | |
| GSE97050 | ULBP2 | 80328 | A_23_P145485 | 0.8395 | 0.3795 | |
| SRP007169 | ULBP2 | 80328 | RNAseq | 0.7655 | 0.1301 | |
| SRP008496 | ULBP2 | 80328 | RNAseq | 0.7939 | 0.0792 | |
| SRP064894 | ULBP2 | 80328 | RNAseq | 2.2008 | 0.0000 | |
| SRP133303 | ULBP2 | 80328 | RNAseq | 2.5955 | 0.0000 | |
| SRP159526 | ULBP2 | 80328 | RNAseq | 1.1554 | 0.0018 | |
| SRP219564 | ULBP2 | 80328 | RNAseq | 0.6276 | 0.4750 | |
| TCGA | ULBP2 | 80328 | RNAseq | 2.4299 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by ULBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ULBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ULBP2 | 80328 | 2 | 4 | 24 | |
| GSE20123 | ULBP2 | 80328 | 2 | 3 | 25 | |
| GSE43470 | ULBP2 | 80328 | 4 | 0 | 39 | |
| GSE46452 | ULBP2 | 80328 | 3 | 10 | 46 | |
| GSE47630 | ULBP2 | 80328 | 9 | 4 | 27 | |
| GSE54993 | ULBP2 | 80328 | 3 | 2 | 65 | |
| GSE54994 | ULBP2 | 80328 | 8 | 8 | 37 | |
| GSE60625 | ULBP2 | 80328 | 0 | 1 | 10 | |
| GSE74703 | ULBP2 | 80328 | 4 | 0 | 32 | |
| GSE74704 | ULBP2 | 80328 | 0 | 1 | 19 | |
| TCGA | ULBP2 | 80328 | 11 | 21 | 64 |
Total number of gains: 46; Total number of losses: 54; Total Number of normals: 388.
Somatic mutations of ULBP2:
Generating mutation plots.
Highly correlated genes for ULBP2:
Showing top 20/562 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ULBP2 | RAET1G | 0.83079 | 3 | 0 | 3 |
| ULBP2 | KRT5 | 0.790593 | 4 | 0 | 4 |
| ULBP2 | KRT6C | 0.744193 | 4 | 0 | 3 |
| ULBP2 | CERS3 | 0.711413 | 4 | 0 | 3 |
| ULBP2 | EPHA1 | 0.709169 | 8 | 0 | 8 |
| ULBP2 | GRHL2 | 0.704989 | 3 | 0 | 3 |
| ULBP2 | SLC27A4 | 0.69372 | 5 | 0 | 4 |
| ULBP2 | SLC10A6 | 0.691128 | 3 | 0 | 3 |
| ULBP2 | PLEKHN1 | 0.686284 | 3 | 0 | 3 |
| ULBP2 | MREG | 0.684515 | 8 | 0 | 7 |
| ULBP2 | FAM83C | 0.68367 | 4 | 0 | 3 |
| ULBP2 | RASAL2 | 0.677786 | 6 | 0 | 6 |
| ULBP2 | GJB5 | 0.676508 | 9 | 0 | 7 |
| ULBP2 | PRDM1 | 0.675559 | 9 | 0 | 8 |
| ULBP2 | ZDHHC5 | 0.67132 | 3 | 0 | 3 |
| ULBP2 | DSC3 | 0.67032 | 8 | 0 | 6 |
| ULBP2 | FXYD3 | 0.669535 | 3 | 0 | 3 |
| ULBP2 | ARNTL2 | 0.668477 | 8 | 0 | 7 |
| ULBP2 | KCTD11 | 0.667993 | 3 | 0 | 3 |
| ULBP2 | RTKN2 | 0.665275 | 3 | 0 | 3 |
For details and further investigation, click here
