| Full name: scratch family transcriptional repressor 1 | Alias Symbol: DKFZp547F072|ZNF898 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 83482 | HGNC ID: HGNC:15950 | Ensembl Gene: ENSG00000261678 | OMIM ID: 605858 |
| Drug and gene relationship at DGIdb | |||
Expression of SCRT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCRT1 | 83482 | 228761_at | 0.0521 | 0.8485 | |
| GSE20347 | SCRT1 | 83482 | 221026_s_at | -0.0196 | 0.7670 | |
| GSE23400 | SCRT1 | 83482 | 221026_s_at | -0.1551 | 0.0000 | |
| GSE26886 | SCRT1 | 83482 | 228761_at | 0.1694 | 0.1302 | |
| GSE29001 | SCRT1 | 83482 | 221026_s_at | -0.0371 | 0.7297 | |
| GSE38129 | SCRT1 | 83482 | 221026_s_at | -0.0326 | 0.5584 | |
| GSE45670 | SCRT1 | 83482 | 228761_at | 0.1953 | 0.0069 | |
| GSE53622 | SCRT1 | 83482 | 61355 | 0.0506 | 0.6731 | |
| GSE53624 | SCRT1 | 83482 | 58967 | 0.2344 | 0.0368 | |
| GSE63941 | SCRT1 | 83482 | 228761_at | 0.0528 | 0.7542 | |
| GSE77861 | SCRT1 | 83482 | 228761_at | -0.0020 | 0.9880 | |
| TCGA | SCRT1 | 83482 | RNAseq | -0.3824 | 0.6530 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SCRT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCRT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCRT1 | 83482 | 17 | 1 | 12 | |
| GSE20123 | SCRT1 | 83482 | 17 | 1 | 12 | |
| GSE43470 | SCRT1 | 83482 | 16 | 2 | 25 | |
| GSE46452 | SCRT1 | 83482 | 28 | 0 | 31 | |
| GSE47630 | SCRT1 | 83482 | 25 | 1 | 14 | |
| GSE54993 | SCRT1 | 83482 | 0 | 25 | 45 | |
| GSE54994 | SCRT1 | 83482 | 39 | 1 | 13 | |
| GSE60625 | SCRT1 | 83482 | 3 | 4 | 4 | |
| GSE74703 | SCRT1 | 83482 | 14 | 1 | 21 | |
| GSE74704 | SCRT1 | 83482 | 10 | 0 | 10 | |
| TCGA | SCRT1 | 83482 | 63 | 2 | 31 |
Total number of gains: 232; Total number of losses: 38; Total Number of normals: 218.
Somatic mutations of SCRT1:
Generating mutation plots.
Highly correlated genes for SCRT1:
Showing top 20/56 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCRT1 | CC2D1B | 0.646221 | 3 | 0 | 3 |
| SCRT1 | ZNF598 | 0.621796 | 3 | 0 | 3 |
| SCRT1 | NOX5 | 0.617482 | 3 | 0 | 3 |
| SCRT1 | KCNC3 | 0.611663 | 4 | 0 | 3 |
| SCRT1 | FBXL19-AS1 | 0.610566 | 3 | 0 | 3 |
| SCRT1 | SH3D21 | 0.603042 | 4 | 0 | 4 |
| SCRT1 | LYPLA2 | 0.602377 | 4 | 0 | 4 |
| SCRT1 | ICOSLG | 0.602357 | 3 | 0 | 3 |
| SCRT1 | OBSCN | 0.586696 | 4 | 0 | 4 |
| SCRT1 | ADCY1 | 0.583293 | 3 | 0 | 3 |
| SCRT1 | CYP2D6 | 0.581188 | 5 | 0 | 4 |
| SCRT1 | INPP5J | 0.579364 | 4 | 0 | 4 |
| SCRT1 | NOS1 | 0.57743 | 5 | 0 | 4 |
| SCRT1 | DPEP1 | 0.574478 | 4 | 0 | 3 |
| SCRT1 | KRT36 | 0.574365 | 3 | 0 | 3 |
| SCRT1 | CAPN10 | 0.573505 | 4 | 0 | 4 |
| SCRT1 | FARP2 | 0.567893 | 3 | 0 | 3 |
| SCRT1 | EPHB2 | 0.564294 | 3 | 0 | 3 |
| SCRT1 | NEUROG1 | 0.560254 | 4 | 0 | 3 |
| SCRT1 | LTK | 0.559814 | 3 | 0 | 3 |
For details and further investigation, click here
