| Full name: SEC14 like lipid binding 1 | Alias Symbol: PRELID4A | ||
| Type: protein-coding gene | Cytoband: 17q25.2-q25.3 | ||
| Entrez ID: 6397 | HGNC ID: HGNC:10698 | Ensembl Gene: ENSG00000129657 | OMIM ID: 601504 |
| Drug and gene relationship at DGIdb | |||
Expression of SEC14L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC14L1 | 6397 | 202084_s_at | -0.2813 | 0.5442 | |
| GSE20347 | SEC14L1 | 6397 | 202084_s_at | -0.3926 | 0.0052 | |
| GSE23400 | SEC14L1 | 6397 | 202084_s_at | -0.4372 | 0.0000 | |
| GSE26886 | SEC14L1 | 6397 | 202084_s_at | -0.8191 | 0.0014 | |
| GSE29001 | SEC14L1 | 6397 | 202084_s_at | -0.7321 | 0.0403 | |
| GSE38129 | SEC14L1 | 6397 | 202084_s_at | -0.3993 | 0.0292 | |
| GSE45670 | SEC14L1 | 6397 | 202084_s_at | -0.6141 | 0.0020 | |
| GSE53622 | SEC14L1 | 6397 | 128925 | -0.3301 | 0.0000 | |
| GSE53624 | SEC14L1 | 6397 | 128925 | -0.4624 | 0.0000 | |
| GSE63941 | SEC14L1 | 6397 | 202084_s_at | 0.0772 | 0.8965 | |
| GSE77861 | SEC14L1 | 6397 | 202084_s_at | -0.1715 | 0.5365 | |
| GSE97050 | SEC14L1 | A_19_P00320158 | 0.1319 | 0.4885 | ||
| SRP007169 | SEC14L1 | 6397 | RNAseq | -1.3032 | 0.0080 | |
| SRP008496 | SEC14L1 | 6397 | RNAseq | -1.8370 | 0.0000 | |
| SRP064894 | SEC14L1 | 6397 | RNAseq | -1.0715 | 0.0000 | |
| SRP133303 | SEC14L1 | 6397 | RNAseq | -0.1125 | 0.4753 | |
| SRP159526 | SEC14L1 | 6397 | RNAseq | -0.3622 | 0.2766 | |
| SRP193095 | SEC14L1 | 6397 | RNAseq | -0.8209 | 0.0000 | |
| SRP219564 | SEC14L1 | 6397 | RNAseq | -0.7657 | 0.1019 | |
| TCGA | SEC14L1 | 6397 | RNAseq | -0.3103 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SEC14L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC14L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC14L1 | 6397 | 7 | 2 | 21 | |
| GSE20123 | SEC14L1 | 6397 | 7 | 2 | 21 | |
| GSE43470 | SEC14L1 | 6397 | 4 | 4 | 35 | |
| GSE46452 | SEC14L1 | 6397 | 33 | 1 | 25 | |
| GSE47630 | SEC14L1 | 6397 | 8 | 1 | 31 | |
| GSE54993 | SEC14L1 | 6397 | 2 | 5 | 63 | |
| GSE54994 | SEC14L1 | 6397 | 10 | 4 | 39 | |
| GSE60625 | SEC14L1 | 6397 | 6 | 0 | 5 | |
| GSE74703 | SEC14L1 | 6397 | 4 | 2 | 30 | |
| GSE74704 | SEC14L1 | 6397 | 5 | 1 | 14 | |
| TCGA | SEC14L1 | 6397 | 31 | 9 | 56 |
Total number of gains: 117; Total number of losses: 31; Total Number of normals: 340.
Somatic mutations of SEC14L1:
Generating mutation plots.
Highly correlated genes for SEC14L1:
Showing top 20/138 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC14L1 | BCDIN3D | 0.749186 | 3 | 0 | 3 |
| SEC14L1 | SCARA5 | 0.705186 | 3 | 0 | 3 |
| SEC14L1 | PTPRN2 | 0.685951 | 3 | 0 | 3 |
| SEC14L1 | IQCD | 0.684949 | 3 | 0 | 3 |
| SEC14L1 | WDR60 | 0.677767 | 3 | 0 | 3 |
| SEC14L1 | BRAF | 0.676824 | 4 | 0 | 3 |
| SEC14L1 | LDB2 | 0.675211 | 4 | 0 | 4 |
| SEC14L1 | NPR1 | 0.672653 | 3 | 0 | 3 |
| SEC14L1 | ESAM | 0.662317 | 7 | 0 | 6 |
| SEC14L1 | GPR146 | 0.660582 | 3 | 0 | 3 |
| SEC14L1 | GALNT5 | 0.658877 | 3 | 0 | 3 |
| SEC14L1 | FAM110B | 0.653553 | 4 | 0 | 4 |
| SEC14L1 | HSPA12B | 0.64013 | 3 | 0 | 3 |
| SEC14L1 | KCTD5 | 0.622768 | 5 | 0 | 3 |
| SEC14L1 | ADRA2A | 0.615075 | 4 | 0 | 3 |
| SEC14L1 | FAM219B | 0.613551 | 3 | 0 | 3 |
| SEC14L1 | SPNS3 | 0.612123 | 4 | 0 | 4 |
| SEC14L1 | GCHFR | 0.608602 | 7 | 0 | 7 |
| SEC14L1 | FAM171A1 | 0.604625 | 4 | 0 | 3 |
| SEC14L1 | DNASE1 | 0.602712 | 5 | 0 | 4 |
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