| Full name: serpin family I member 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q26.1 | ||
| Entrez ID: 5274 | HGNC ID: HGNC:8943 | Ensembl Gene: ENSG00000163536 | OMIM ID: 602445 |
| Drug and gene relationship at DGIdb | |||
Expression of SERPINI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERPINI1 | 5274 | 205352_at | 0.5819 | 0.3584 | |
| GSE20347 | SERPINI1 | 5274 | 205352_at | 0.3593 | 0.1811 | |
| GSE23400 | SERPINI1 | 5274 | 205352_at | 0.0112 | 0.8493 | |
| GSE26886 | SERPINI1 | 5274 | 205352_at | -0.5875 | 0.1043 | |
| GSE29001 | SERPINI1 | 5274 | 205352_at | 0.0449 | 0.9366 | |
| GSE38129 | SERPINI1 | 5274 | 205352_at | 0.1163 | 0.7211 | |
| GSE45670 | SERPINI1 | 5274 | 205352_at | -0.4954 | 0.2216 | |
| GSE53622 | SERPINI1 | 5274 | 11600 | 0.1738 | 0.2798 | |
| GSE53624 | SERPINI1 | 5274 | 11600 | 0.0239 | 0.9188 | |
| GSE63941 | SERPINI1 | 5274 | 205352_at | -1.3697 | 0.3986 | |
| GSE77861 | SERPINI1 | 5274 | 205352_at | 0.7909 | 0.2227 | |
| GSE97050 | SERPINI1 | 5274 | A_23_P166929 | 0.0055 | 0.9848 | |
| SRP007169 | SERPINI1 | 5274 | RNAseq | 1.5588 | 0.0357 | |
| SRP064894 | SERPINI1 | 5274 | RNAseq | -0.0152 | 0.9394 | |
| SRP133303 | SERPINI1 | 5274 | RNAseq | 0.1804 | 0.4961 | |
| SRP159526 | SERPINI1 | 5274 | RNAseq | 0.6453 | 0.1228 | |
| SRP193095 | SERPINI1 | 5274 | RNAseq | 0.2810 | 0.2865 | |
| SRP219564 | SERPINI1 | 5274 | RNAseq | -0.1028 | 0.8349 | |
| TCGA | SERPINI1 | 5274 | RNAseq | -0.4617 | 0.0052 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SERPINI1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERPINI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERPINI1 | 5274 | 22 | 0 | 8 | |
| GSE20123 | SERPINI1 | 5274 | 22 | 0 | 8 | |
| GSE43470 | SERPINI1 | 5274 | 23 | 0 | 20 | |
| GSE46452 | SERPINI1 | 5274 | 19 | 1 | 39 | |
| GSE47630 | SERPINI1 | 5274 | 27 | 2 | 11 | |
| GSE54993 | SERPINI1 | 5274 | 1 | 13 | 56 | |
| GSE54994 | SERPINI1 | 5274 | 41 | 0 | 12 | |
| GSE60625 | SERPINI1 | 5274 | 0 | 6 | 5 | |
| GSE74703 | SERPINI1 | 5274 | 19 | 0 | 17 | |
| GSE74704 | SERPINI1 | 5274 | 14 | 0 | 6 | |
| TCGA | SERPINI1 | 5274 | 79 | 0 | 17 |
Total number of gains: 267; Total number of losses: 22; Total Number of normals: 199.
Somatic mutations of SERPINI1:
Generating mutation plots.
Highly correlated genes for SERPINI1:
Showing top 20/211 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERPINI1 | CMTM4 | 0.724623 | 3 | 0 | 3 |
| SERPINI1 | LRP4 | 0.703507 | 3 | 0 | 3 |
| SERPINI1 | TMEM181 | 0.682673 | 3 | 0 | 3 |
| SERPINI1 | NUFIP2 | 0.66499 | 4 | 0 | 4 |
| SERPINI1 | WDR75 | 0.653101 | 3 | 0 | 3 |
| SERPINI1 | SFXN4 | 0.649026 | 3 | 0 | 3 |
| SERPINI1 | USP45 | 0.647535 | 4 | 0 | 3 |
| SERPINI1 | CHTOP | 0.644166 | 4 | 0 | 3 |
| SERPINI1 | PSAT1 | 0.641007 | 4 | 0 | 3 |
| SERPINI1 | CLK2 | 0.638419 | 3 | 0 | 3 |
| SERPINI1 | USP21 | 0.63667 | 4 | 0 | 4 |
| SERPINI1 | FZD6 | 0.634286 | 3 | 0 | 3 |
| SERPINI1 | GTF3C2 | 0.628278 | 3 | 0 | 3 |
| SERPINI1 | METTL14 | 0.627813 | 3 | 0 | 3 |
| SERPINI1 | THAP6 | 0.624475 | 3 | 0 | 3 |
| SERPINI1 | DDX59 | 0.622669 | 4 | 0 | 3 |
| SERPINI1 | RMND1 | 0.62182 | 4 | 0 | 3 |
| SERPINI1 | ZNF202 | 0.61972 | 3 | 0 | 3 |
| SERPINI1 | NUP35 | 0.616453 | 4 | 0 | 3 |
| SERPINI1 | CNPY2 | 0.61629 | 4 | 0 | 4 |
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