| Full name: canopy FGF signaling regulator 2 | Alias Symbol: HP10390|ZSIG9|Cnpy2 | ||
| Type: protein-coding gene | Cytoband: 12q13.3 | ||
| Entrez ID: 10330 | HGNC ID: HGNC:13529 | Ensembl Gene: ENSG00000257727 | OMIM ID: 605861 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CNPY2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNPY2 | 10330 | 202857_at | 0.3862 | 0.1252 | |
| GSE20347 | CNPY2 | 10330 | 202857_at | 0.4805 | 0.0029 | |
| GSE23400 | CNPY2 | 10330 | 202857_at | 0.7013 | 0.0000 | |
| GSE26886 | CNPY2 | 10330 | 202857_at | 0.3407 | 0.0704 | |
| GSE29001 | CNPY2 | 10330 | 202857_at | 0.4725 | 0.0695 | |
| GSE38129 | CNPY2 | 10330 | 202857_at | 0.5880 | 0.0000 | |
| GSE45670 | CNPY2 | 10330 | 202857_at | 0.4910 | 0.0005 | |
| GSE53622 | CNPY2 | 10330 | 25422 | 0.4315 | 0.0000 | |
| GSE53624 | CNPY2 | 10330 | 25422 | 0.5574 | 0.0000 | |
| GSE63941 | CNPY2 | 10330 | 202857_at | -0.5318 | 0.1010 | |
| GSE77861 | CNPY2 | 10330 | 202857_at | 0.3709 | 0.1990 | |
| GSE97050 | CNPY2 | 10330 | A_23_P53288 | 0.4034 | 0.2297 | |
| SRP007169 | CNPY2 | 10330 | RNAseq | 0.2323 | 0.6041 | |
| SRP008496 | CNPY2 | 10330 | RNAseq | 0.4823 | 0.0836 | |
| SRP064894 | CNPY2 | 10330 | RNAseq | 0.5463 | 0.0395 | |
| SRP133303 | CNPY2 | 10330 | RNAseq | 0.4648 | 0.0011 | |
| SRP159526 | CNPY2 | 10330 | RNAseq | 0.4972 | 0.0499 | |
| SRP193095 | CNPY2 | 10330 | RNAseq | 0.0390 | 0.7756 | |
| SRP219564 | CNPY2 | 10330 | RNAseq | 0.4618 | 0.1410 | |
| TCGA | CNPY2 | 10330 | RNAseq | 0.0658 | 0.2432 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CNPY2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNPY2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNPY2 | 10330 | 7 | 2 | 21 | |
| GSE20123 | CNPY2 | 10330 | 7 | 1 | 22 | |
| GSE43470 | CNPY2 | 10330 | 4 | 0 | 39 | |
| GSE46452 | CNPY2 | 10330 | 8 | 1 | 50 | |
| GSE47630 | CNPY2 | 10330 | 10 | 2 | 28 | |
| GSE54993 | CNPY2 | 10330 | 0 | 5 | 65 | |
| GSE54994 | CNPY2 | 10330 | 4 | 1 | 48 | |
| GSE60625 | CNPY2 | 10330 | 0 | 0 | 11 | |
| GSE74703 | CNPY2 | 10330 | 4 | 0 | 32 | |
| GSE74704 | CNPY2 | 10330 | 4 | 1 | 15 | |
| TCGA | CNPY2 | 10330 | 14 | 10 | 72 |
Total number of gains: 62; Total number of losses: 23; Total Number of normals: 403.
Somatic mutations of CNPY2:
Generating mutation plots.
Highly correlated genes for CNPY2:
Showing top 20/1153 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNPY2 | SLC35B2 | 0.762977 | 3 | 0 | 3 |
| CNPY2 | ZAP70 | 0.756114 | 3 | 0 | 3 |
| CNPY2 | HEXA | 0.733107 | 5 | 0 | 5 |
| CNPY2 | CDCA2 | 0.727455 | 4 | 0 | 4 |
| CNPY2 | PDIA5 | 0.720163 | 3 | 0 | 3 |
| CNPY2 | POC5 | 0.703279 | 3 | 0 | 3 |
| CNPY2 | KTI12 | 0.69797 | 3 | 0 | 3 |
| CNPY2 | CCNB2 | 0.694737 | 9 | 0 | 9 |
| CNPY2 | PYCR2 | 0.692929 | 3 | 0 | 3 |
| CNPY2 | DNAJB11 | 0.691697 | 6 | 0 | 6 |
| CNPY2 | PMS2 | 0.68808 | 3 | 0 | 3 |
| CNPY2 | KREMEN1 | 0.686918 | 3 | 0 | 3 |
| CNPY2 | KIAA1522 | 0.682602 | 3 | 0 | 3 |
| CNPY2 | SMARCAD1 | 0.678707 | 4 | 0 | 4 |
| CNPY2 | STEAP1B | 0.678536 | 3 | 0 | 3 |
| CNPY2 | FBXO5 | 0.677582 | 10 | 0 | 9 |
| CNPY2 | TNFSF13 | 0.67305 | 3 | 0 | 3 |
| CNPY2 | CXCL16 | 0.673046 | 4 | 0 | 3 |
| CNPY2 | HSD17B1 | 0.672423 | 4 | 0 | 3 |
| CNPY2 | FCHO1 | 0.672333 | 3 | 0 | 3 |
For details and further investigation, click here
