| Full name: solute carrier family 44 member 5 | Alias Symbol: MGC34032|CTL5 | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 204962 | HGNC ID: HGNC:28524 | Ensembl Gene: ENSG00000137968 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
SLC44A5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05231 | Choline metabolism in cancer |
Expression of SLC44A5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC44A5 | 204962 | 235763_at | 2.0945 | 0.2332 | |
| GSE26886 | SLC44A5 | 204962 | 235763_at | 1.8285 | 0.0846 | |
| GSE45670 | SLC44A5 | 204962 | 235763_at | 3.8990 | 0.0000 | |
| GSE53622 | SLC44A5 | 204962 | 40000 | 2.7553 | 0.0000 | |
| GSE53624 | SLC44A5 | 204962 | 40000 | 2.3931 | 0.0000 | |
| GSE63941 | SLC44A5 | 204962 | 235763_at | 3.6766 | 0.0034 | |
| GSE77861 | SLC44A5 | 204962 | 1569112_at | 0.4448 | 0.3414 | |
| GSE97050 | SLC44A5 | 204962 | A_23_P342641 | 0.8888 | 0.2616 | |
| SRP133303 | SLC44A5 | 204962 | RNAseq | 1.2256 | 0.0509 | |
| SRP159526 | SLC44A5 | 204962 | RNAseq | 3.7836 | 0.0000 | |
| SRP193095 | SLC44A5 | 204962 | RNAseq | 1.9530 | 0.0000 | |
| TCGA | SLC44A5 | 204962 | RNAseq | 0.9769 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SLC44A5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC44A5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC44A5 | 204962 | 0 | 7 | 23 | |
| GSE20123 | SLC44A5 | 204962 | 0 | 7 | 23 | |
| GSE43470 | SLC44A5 | 204962 | 4 | 4 | 35 | |
| GSE46452 | SLC44A5 | 204962 | 0 | 1 | 58 | |
| GSE47630 | SLC44A5 | 204962 | 8 | 6 | 26 | |
| GSE54993 | SLC44A5 | 204962 | 0 | 0 | 70 | |
| GSE54994 | SLC44A5 | 204962 | 6 | 3 | 44 | |
| GSE60625 | SLC44A5 | 204962 | 0 | 0 | 11 | |
| GSE74703 | SLC44A5 | 204962 | 3 | 3 | 30 | |
| GSE74704 | SLC44A5 | 204962 | 0 | 4 | 16 | |
| TCGA | SLC44A5 | 204962 | 8 | 25 | 63 |
Total number of gains: 29; Total number of losses: 60; Total Number of normals: 399.
Somatic mutations of SLC44A5:
Generating mutation plots.
Highly correlated genes for SLC44A5:
Showing top 20/385 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC44A5 | TM9SF4 | 0.737133 | 3 | 0 | 3 |
| SLC44A5 | INO80B | 0.661569 | 3 | 0 | 3 |
| SLC44A5 | SLC6A14 | 0.657863 | 3 | 0 | 3 |
| SLC44A5 | VANGL2 | 0.639862 | 4 | 0 | 4 |
| SLC44A5 | LRP8 | 0.636116 | 3 | 0 | 3 |
| SLC44A5 | RPARP-AS1 | 0.632837 | 3 | 0 | 3 |
| SLC44A5 | WDR72 | 0.626377 | 6 | 0 | 4 |
| SLC44A5 | PTK7 | 0.621752 | 5 | 0 | 4 |
| SLC44A5 | COL10A1 | 0.62158 | 3 | 0 | 3 |
| SLC44A5 | TMC6 | 0.620558 | 4 | 0 | 4 |
| SLC44A5 | FAM91A1 | 0.618937 | 5 | 0 | 3 |
| SLC44A5 | CELSR1 | 0.615455 | 4 | 0 | 3 |
| SLC44A5 | POMZP3 | 0.61084 | 3 | 0 | 3 |
| SLC44A5 | CEP85 | 0.610811 | 6 | 0 | 5 |
| SLC44A5 | HOXA10 | 0.61067 | 4 | 0 | 4 |
| SLC44A5 | MYBL2 | 0.610059 | 6 | 0 | 6 |
| SLC44A5 | SYT7 | 0.604717 | 4 | 0 | 3 |
| SLC44A5 | CDC25B | 0.603218 | 6 | 0 | 6 |
| SLC44A5 | EWSR1 | 0.603188 | 3 | 0 | 3 |
| SLC44A5 | LAPTM4B | 0.602587 | 7 | 0 | 6 |
For details and further investigation, click here
