| Full name: solute carrier family 51 alpha subunit | Alias Symbol: OSTalpha | ||
| Type: protein-coding gene | Cytoband: 3q29 | ||
| Entrez ID: 200931 | HGNC ID: HGNC:29955 | Ensembl Gene: ENSG00000163959 | OMIM ID: 612084 |
| Drug and gene relationship at DGIdb | |||
SLC51A involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04976 | Bile secretion |
Expression of SLC51A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC51A | 200931 | 229230_at | 0.3927 | 0.6305 | |
| GSE26886 | SLC51A | 200931 | 229230_at | 0.3887 | 0.3898 | |
| GSE45670 | SLC51A | 200931 | 229230_at | 0.4730 | 0.0993 | |
| GSE53622 | SLC51A | 200931 | 12146 | 0.2281 | 0.2844 | |
| GSE53624 | SLC51A | 200931 | 12146 | 0.2658 | 0.0729 | |
| GSE63941 | SLC51A | 200931 | 229230_at | 0.2887 | 0.5083 | |
| GSE77861 | SLC51A | 200931 | 229230_at | -0.0413 | 0.8671 | |
| SRP064894 | SLC51A | 200931 | RNAseq | 1.1347 | 0.0007 | |
| SRP133303 | SLC51A | 200931 | RNAseq | 1.4510 | 0.0054 | |
| SRP159526 | SLC51A | 200931 | RNAseq | 0.6050 | 0.3310 | |
| SRP193095 | SLC51A | 200931 | RNAseq | -0.4396 | 0.2567 | |
| SRP219564 | SLC51A | 200931 | RNAseq | 1.4931 | 0.0093 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SLC51A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SLC51A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC51A | 200931 | 22 | 0 | 8 | |
| GSE20123 | SLC51A | 200931 | 22 | 0 | 8 | |
| GSE43470 | SLC51A | 200931 | 21 | 0 | 22 | |
| GSE46452 | SLC51A | 200931 | 19 | 1 | 39 | |
| GSE47630 | SLC51A | 200931 | 27 | 2 | 11 | |
| GSE54993 | SLC51A | 200931 | 1 | 22 | 47 | |
| GSE54994 | SLC51A | 200931 | 41 | 0 | 12 | |
| GSE60625 | SLC51A | 200931 | 0 | 6 | 5 | |
| GSE74703 | SLC51A | 200931 | 19 | 0 | 17 | |
| GSE74704 | SLC51A | 200931 | 14 | 0 | 6 | |
| TCGA | SLC51A | 200931 | 77 | 0 | 19 |
Total number of gains: 263; Total number of losses: 31; Total Number of normals: 194.
Somatic mutations of SLC51A:
Generating mutation plots.
Highly correlated genes for SLC51A:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC51A | BCAS1 | 0.681647 | 3 | 0 | 3 |
| SLC51A | CLIC6 | 0.676896 | 3 | 0 | 3 |
| SLC51A | IDO1 | 0.671622 | 3 | 0 | 3 |
| SLC51A | KDM4A | 0.664851 | 3 | 0 | 3 |
| SLC51A | MSLN | 0.653109 | 3 | 0 | 3 |
| SLC51A | ATP7B | 0.635693 | 3 | 0 | 3 |
| SLC51A | MIB2 | 0.627604 | 3 | 0 | 3 |
| SLC51A | AP3M2 | 0.617585 | 3 | 0 | 3 |
| SLC51A | PARK7 | 0.604723 | 3 | 0 | 3 |
| SLC51A | TCEANC | 0.60108 | 3 | 0 | 3 |
| SLC51A | GPR158 | 0.593527 | 3 | 0 | 3 |
| SLC51A | ELOVL2-AS1 | 0.58851 | 3 | 0 | 3 |
| SLC51A | KLK3 | 0.579946 | 3 | 0 | 3 |
| SLC51A | TSPAN1 | 0.577915 | 5 | 0 | 4 |
| SLC51A | PRR15 | 0.574923 | 5 | 0 | 3 |
| SLC51A | BTG1 | 0.569743 | 3 | 0 | 3 |
| SLC51A | ZAP70 | 0.559549 | 4 | 0 | 3 |
| SLC51A | WDTC1 | 0.554639 | 3 | 0 | 3 |
| SLC51A | BCL2L14 | 0.540201 | 5 | 0 | 3 |
| SLC51A | PLEKHH1 | 0.528223 | 3 | 0 | 3 |
For details and further investigation, click here
