| Full name: nuclear receptor coactivator 7 | Alias Symbol: ERAP140|dJ187J11.3|TLDC4 | ||
| Type: protein-coding gene | Cytoband: 6q22.31-q22.32 | ||
| Entrez ID: 135112 | HGNC ID: HGNC:21081 | Ensembl Gene: ENSG00000111912 | OMIM ID: 609752 |
| Drug and gene relationship at DGIdb | |||
Expression of NCOA7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCOA7 | 135112 | 225344_at | -0.0269 | 0.9826 | |
| GSE26886 | NCOA7 | 135112 | 225344_at | -0.2198 | 0.6556 | |
| GSE45670 | NCOA7 | 135112 | 225344_at | 0.3435 | 0.1543 | |
| GSE53622 | NCOA7 | 135112 | 20278 | -0.0287 | 0.8430 | |
| GSE53624 | NCOA7 | 135112 | 20278 | -0.1862 | 0.1141 | |
| GSE63941 | NCOA7 | 135112 | 225344_at | -0.0373 | 0.9767 | |
| GSE77861 | NCOA7 | 135112 | 225344_at | -0.3056 | 0.5660 | |
| GSE97050 | NCOA7 | 135112 | A_24_P12435 | 0.8875 | 0.1247 | |
| SRP007169 | NCOA7 | 135112 | RNAseq | -0.4618 | 0.2893 | |
| SRP008496 | NCOA7 | 135112 | RNAseq | -0.9404 | 0.1968 | |
| SRP064894 | NCOA7 | 135112 | RNAseq | 0.1735 | 0.5797 | |
| SRP133303 | NCOA7 | 135112 | RNAseq | 0.4176 | 0.1023 | |
| SRP159526 | NCOA7 | 135112 | RNAseq | 0.5016 | 0.2570 | |
| SRP193095 | NCOA7 | 135112 | RNAseq | 0.3572 | 0.1722 | |
| SRP219564 | NCOA7 | 135112 | RNAseq | -0.4222 | 0.5190 | |
| TCGA | NCOA7 | 135112 | RNAseq | 0.1008 | 0.2150 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NCOA7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCOA7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCOA7 | 135112 | 1 | 4 | 25 | |
| GSE20123 | NCOA7 | 135112 | 2 | 3 | 25 | |
| GSE43470 | NCOA7 | 135112 | 5 | 0 | 38 | |
| GSE46452 | NCOA7 | 135112 | 2 | 11 | 46 | |
| GSE47630 | NCOA7 | 135112 | 9 | 4 | 27 | |
| GSE54993 | NCOA7 | 135112 | 4 | 2 | 64 | |
| GSE54994 | NCOA7 | 135112 | 8 | 8 | 37 | |
| GSE60625 | NCOA7 | 135112 | 0 | 1 | 10 | |
| GSE74703 | NCOA7 | 135112 | 4 | 0 | 32 | |
| GSE74704 | NCOA7 | 135112 | 0 | 1 | 19 | |
| TCGA | NCOA7 | 135112 | 12 | 18 | 66 |
Total number of gains: 47; Total number of losses: 52; Total Number of normals: 389.
Somatic mutations of NCOA7:
Generating mutation plots.
Highly correlated genes for NCOA7:
Showing top 20/91 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCOA7 | CXCL3 | 0.769888 | 3 | 0 | 3 |
| NCOA7 | ALG8 | 0.730812 | 3 | 0 | 3 |
| NCOA7 | GPR65 | 0.716022 | 3 | 0 | 3 |
| NCOA7 | CCL28 | 0.714952 | 3 | 0 | 3 |
| NCOA7 | TXNDC11 | 0.71441 | 3 | 0 | 3 |
| NCOA7 | VDAC3 | 0.678592 | 3 | 0 | 3 |
| NCOA7 | SDHB | 0.669823 | 3 | 0 | 3 |
| NCOA7 | SPRR4 | 0.666715 | 3 | 0 | 3 |
| NCOA7 | SEMA6A | 0.661971 | 3 | 0 | 3 |
| NCOA7 | SLC43A3 | 0.654772 | 4 | 0 | 3 |
| NCOA7 | MRPS11 | 0.650231 | 3 | 0 | 3 |
| NCOA7 | C10orf88 | 0.645978 | 3 | 0 | 3 |
| NCOA7 | SH2B3 | 0.645668 | 3 | 0 | 3 |
| NCOA7 | ARHGEF6 | 0.643574 | 3 | 0 | 3 |
| NCOA7 | MANEA | 0.643505 | 3 | 0 | 3 |
| NCOA7 | CCL22 | 0.643399 | 3 | 0 | 3 |
| NCOA7 | TM4SF18 | 0.642795 | 4 | 0 | 3 |
| NCOA7 | C16orf54 | 0.637572 | 3 | 0 | 3 |
| NCOA7 | TNFAIP2 | 0.637201 | 4 | 0 | 4 |
| NCOA7 | TRIB1 | 0.633802 | 4 | 0 | 3 |
For details and further investigation, click here
