| Full name: ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 | Alias Symbol: ST6GALNACIV|SIAT3C | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 27090 | HGNC ID: HGNC:17846 | Ensembl Gene: ENSG00000136840 | OMIM ID: 606378 |
| Drug and gene relationship at DGIdb | |||
Expression of ST6GALNAC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST6GALNAC4 | 27090 | 220937_s_at | 0.2488 | 0.5454 | |
| GSE20347 | ST6GALNAC4 | 27090 | 220937_s_at | 0.1405 | 0.2136 | |
| GSE23400 | ST6GALNAC4 | 27090 | 221551_x_at | -0.0441 | 0.3159 | |
| GSE26886 | ST6GALNAC4 | 27090 | 220937_s_at | 0.2385 | 0.0813 | |
| GSE29001 | ST6GALNAC4 | 27090 | 221551_x_at | -0.0492 | 0.6789 | |
| GSE38129 | ST6GALNAC4 | 27090 | 220937_s_at | 0.2696 | 0.0115 | |
| GSE45670 | ST6GALNAC4 | 27090 | 221551_x_at | 0.0422 | 0.7789 | |
| GSE53622 | ST6GALNAC4 | 27090 | 7063 | 0.2016 | 0.0151 | |
| GSE53624 | ST6GALNAC4 | 27090 | 7063 | -0.1450 | 0.0486 | |
| GSE63941 | ST6GALNAC4 | 27090 | 220937_s_at | -0.4948 | 0.4984 | |
| GSE77861 | ST6GALNAC4 | 27090 | 220937_s_at | -0.1771 | 0.2411 | |
| GSE97050 | ST6GALNAC4 | 27090 | A_23_P94736 | 0.3322 | 0.3408 | |
| SRP007169 | ST6GALNAC4 | 27090 | RNAseq | -0.2701 | 0.5847 | |
| SRP008496 | ST6GALNAC4 | 27090 | RNAseq | -0.0263 | 0.9472 | |
| SRP064894 | ST6GALNAC4 | 27090 | RNAseq | 0.6599 | 0.0224 | |
| SRP133303 | ST6GALNAC4 | 27090 | RNAseq | -0.1089 | 0.5365 | |
| SRP159526 | ST6GALNAC4 | 27090 | RNAseq | 0.1343 | 0.5862 | |
| SRP193095 | ST6GALNAC4 | 27090 | RNAseq | 0.3446 | 0.0555 | |
| SRP219564 | ST6GALNAC4 | 27090 | RNAseq | -0.1538 | 0.7653 | |
| TCGA | ST6GALNAC4 | 27090 | RNAseq | 0.0459 | 0.5650 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ST6GALNAC4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST6GALNAC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST6GALNAC4 | 27090 | 6 | 9 | 15 | |
| GSE20123 | ST6GALNAC4 | 27090 | 6 | 9 | 15 | |
| GSE43470 | ST6GALNAC4 | 27090 | 5 | 7 | 31 | |
| GSE46452 | ST6GALNAC4 | 27090 | 6 | 13 | 40 | |
| GSE47630 | ST6GALNAC4 | 27090 | 3 | 16 | 21 | |
| GSE54993 | ST6GALNAC4 | 27090 | 3 | 3 | 64 | |
| GSE54994 | ST6GALNAC4 | 27090 | 11 | 8 | 34 | |
| GSE60625 | ST6GALNAC4 | 27090 | 0 | 0 | 11 | |
| GSE74703 | ST6GALNAC4 | 27090 | 5 | 5 | 26 | |
| GSE74704 | ST6GALNAC4 | 27090 | 3 | 7 | 10 | |
| TCGA | ST6GALNAC4 | 27090 | 27 | 25 | 44 |
Total number of gains: 75; Total number of losses: 102; Total Number of normals: 311.
Somatic mutations of ST6GALNAC4:
Generating mutation plots.
Highly correlated genes for ST6GALNAC4:
Showing top 20/81 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST6GALNAC4 | SERPINA1 | 0.740404 | 3 | 0 | 3 |
| ST6GALNAC4 | ZNF90 | 0.704547 | 3 | 0 | 3 |
| ST6GALNAC4 | SORL1 | 0.698677 | 3 | 0 | 3 |
| ST6GALNAC4 | PCDH12 | 0.676222 | 4 | 0 | 3 |
| ST6GALNAC4 | ADORA2B | 0.665046 | 3 | 0 | 3 |
| ST6GALNAC4 | CLCN7 | 0.658538 | 3 | 0 | 3 |
| ST6GALNAC4 | RUNX3 | 0.654632 | 3 | 0 | 3 |
| ST6GALNAC4 | CSF3R | 0.654264 | 3 | 0 | 3 |
| ST6GALNAC4 | PRPSAP2 | 0.653447 | 4 | 0 | 4 |
| ST6GALNAC4 | HSPB9 | 0.644593 | 3 | 0 | 3 |
| ST6GALNAC4 | ENG | 0.638273 | 4 | 0 | 3 |
| ST6GALNAC4 | PTPRJ | 0.63036 | 4 | 0 | 3 |
| ST6GALNAC4 | TMEM25 | 0.627352 | 3 | 0 | 3 |
| ST6GALNAC4 | AOAH | 0.624798 | 5 | 0 | 4 |
| ST6GALNAC4 | CHRM4 | 0.622677 | 3 | 0 | 3 |
| ST6GALNAC4 | SLC25A5 | 0.614 | 4 | 0 | 3 |
| ST6GALNAC4 | SMO | 0.610839 | 3 | 0 | 3 |
| ST6GALNAC4 | PIK3AP1 | 0.609271 | 4 | 0 | 3 |
| ST6GALNAC4 | HGF | 0.608014 | 4 | 0 | 3 |
| ST6GALNAC4 | SEC61G | 0.606637 | 4 | 0 | 3 |
For details and further investigation, click here
