| Full name: ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | Alias Symbol: MGC3184|ST6GalNAcV | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 81849 | HGNC ID: HGNC:19342 | Ensembl Gene: ENSG00000117069 | OMIM ID: 610134 |
| Drug and gene relationship at DGIdb | |||
Expression of ST6GALNAC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST6GALNAC5 | 81849 | 230482_at | -0.2911 | 0.5031 | |
| GSE20347 | ST6GALNAC5 | 81849 | 220979_s_at | 0.6993 | 0.0002 | |
| GSE23400 | ST6GALNAC5 | 81849 | 220979_s_at | 0.2417 | 0.0000 | |
| GSE26886 | ST6GALNAC5 | 81849 | 1562753_at | 0.0346 | 0.7293 | |
| GSE29001 | ST6GALNAC5 | 81849 | 220979_s_at | 0.5753 | 0.0351 | |
| GSE38129 | ST6GALNAC5 | 81849 | 220979_s_at | 0.5561 | 0.0510 | |
| GSE45670 | ST6GALNAC5 | 81849 | 230482_at | -0.0346 | 0.9208 | |
| GSE53622 | ST6GALNAC5 | 81849 | 102399 | 0.8917 | 0.0000 | |
| GSE53624 | ST6GALNAC5 | 81849 | 156664 | 1.0322 | 0.0000 | |
| GSE63941 | ST6GALNAC5 | 81849 | 220979_s_at | -2.6536 | 0.0071 | |
| GSE77861 | ST6GALNAC5 | 81849 | 1562753_at | -0.0581 | 0.4861 | |
| GSE97050 | ST6GALNAC5 | 81849 | A_23_P33093 | 0.1639 | 0.6326 | |
| SRP007169 | ST6GALNAC5 | 81849 | RNAseq | 4.6998 | 0.0000 | |
| SRP008496 | ST6GALNAC5 | 81849 | RNAseq | 4.9730 | 0.0000 | |
| SRP064894 | ST6GALNAC5 | 81849 | RNAseq | 0.6911 | 0.0341 | |
| SRP133303 | ST6GALNAC5 | 81849 | RNAseq | 1.6211 | 0.0000 | |
| SRP159526 | ST6GALNAC5 | 81849 | RNAseq | 1.7993 | 0.0015 | |
| SRP219564 | ST6GALNAC5 | 81849 | RNAseq | 0.9630 | 0.1383 | |
| TCGA | ST6GALNAC5 | 81849 | RNAseq | -0.1525 | 0.4742 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by ST6GALNAC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST6GALNAC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST6GALNAC5 | 81849 | 0 | 7 | 23 | |
| GSE20123 | ST6GALNAC5 | 81849 | 0 | 7 | 23 | |
| GSE43470 | ST6GALNAC5 | 81849 | 3 | 4 | 36 | |
| GSE46452 | ST6GALNAC5 | 81849 | 0 | 1 | 58 | |
| GSE47630 | ST6GALNAC5 | 81849 | 8 | 6 | 26 | |
| GSE54993 | ST6GALNAC5 | 81849 | 0 | 0 | 70 | |
| GSE54994 | ST6GALNAC5 | 81849 | 6 | 4 | 43 | |
| GSE60625 | ST6GALNAC5 | 81849 | 0 | 0 | 11 | |
| GSE74703 | ST6GALNAC5 | 81849 | 2 | 3 | 31 | |
| GSE74704 | ST6GALNAC5 | 81849 | 0 | 4 | 16 | |
| TCGA | ST6GALNAC5 | 81849 | 8 | 24 | 64 |
Total number of gains: 27; Total number of losses: 60; Total Number of normals: 401.
Somatic mutations of ST6GALNAC5:
Generating mutation plots.
Highly correlated genes for ST6GALNAC5:
Showing top 20/317 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST6GALNAC5 | CTSK | 0.682265 | 8 | 0 | 7 |
| ST6GALNAC5 | DACT1 | 0.674182 | 8 | 0 | 8 |
| ST6GALNAC5 | SCG5 | 0.673934 | 9 | 0 | 7 |
| ST6GALNAC5 | CSGALNACT1 | 0.661884 | 3 | 0 | 3 |
| ST6GALNAC5 | SAP30 | 0.65916 | 4 | 0 | 3 |
| ST6GALNAC5 | CNTN3 | 0.658829 | 3 | 0 | 3 |
| ST6GALNAC5 | PTGER3 | 0.641645 | 5 | 0 | 4 |
| ST6GALNAC5 | ACVR1 | 0.641538 | 6 | 0 | 6 |
| ST6GALNAC5 | NME5 | 0.63992 | 4 | 0 | 3 |
| ST6GALNAC5 | GPX8 | 0.639184 | 3 | 0 | 3 |
| ST6GALNAC5 | CDH11 | 0.638748 | 7 | 0 | 6 |
| ST6GALNAC5 | VEGFC | 0.6374 | 4 | 0 | 3 |
| ST6GALNAC5 | SERPINA3 | 0.637278 | 4 | 0 | 3 |
| ST6GALNAC5 | ADAMTS12 | 0.635848 | 4 | 0 | 3 |
| ST6GALNAC5 | FAT4 | 0.635269 | 4 | 0 | 3 |
| ST6GALNAC5 | TCEAL7 | 0.629069 | 6 | 0 | 5 |
| ST6GALNAC5 | PLOD1 | 0.626057 | 5 | 0 | 4 |
| ST6GALNAC5 | ANGPTL2 | 0.622879 | 8 | 0 | 6 |
| ST6GALNAC5 | GALNT10 | 0.622093 | 6 | 0 | 5 |
| ST6GALNAC5 | PLA2G15 | 0.621855 | 3 | 0 | 3 |
For details and further investigation, click here
