| Full name: STEAP2 metalloreductase | Alias Symbol: IPCA-1|STAMP1|STMP | ||
| Type: protein-coding gene | Cytoband: 7q21.13 | ||
| Entrez ID: 261729 | HGNC ID: HGNC:17885 | Ensembl Gene: ENSG00000157214 | OMIM ID: 605094 |
| Drug and gene relationship at DGIdb | |||
Expression of STEAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STEAP2 | 261729 | 225871_at | -0.3926 | 0.6884 | |
| GSE26886 | STEAP2 | 261729 | 225871_at | 1.1427 | 0.0006 | |
| GSE45670 | STEAP2 | 261729 | 225871_at | -0.3760 | 0.3076 | |
| GSE53622 | STEAP2 | 261729 | 10657 | 0.4263 | 0.0010 | |
| GSE53624 | STEAP2 | 261729 | 10657 | 0.2556 | 0.0297 | |
| GSE63941 | STEAP2 | 261729 | 225871_at | -2.1196 | 0.0865 | |
| GSE77861 | STEAP2 | 261729 | 225871_at | 0.7885 | 0.2406 | |
| GSE97050 | STEAP2 | 261729 | A_33_P3218925 | 0.5564 | 0.1628 | |
| SRP007169 | STEAP2 | 261729 | RNAseq | 1.1725 | 0.0037 | |
| SRP008496 | STEAP2 | 261729 | RNAseq | 1.4189 | 0.0007 | |
| SRP064894 | STEAP2 | 261729 | RNAseq | 0.5191 | 0.0603 | |
| SRP133303 | STEAP2 | 261729 | RNAseq | 0.7547 | 0.0011 | |
| SRP159526 | STEAP2 | 261729 | RNAseq | 0.6179 | 0.0616 | |
| SRP193095 | STEAP2 | 261729 | RNAseq | 1.3948 | 0.0000 | |
| SRP219564 | STEAP2 | 261729 | RNAseq | 0.7295 | 0.2211 | |
| TCGA | STEAP2 | 261729 | RNAseq | -0.1882 | 0.0706 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by STEAP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STEAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STEAP2 | 261729 | 13 | 1 | 16 | |
| GSE20123 | STEAP2 | 261729 | 13 | 0 | 17 | |
| GSE43470 | STEAP2 | 261729 | 6 | 1 | 36 | |
| GSE46452 | STEAP2 | 261729 | 11 | 0 | 48 | |
| GSE47630 | STEAP2 | 261729 | 9 | 2 | 29 | |
| GSE54993 | STEAP2 | 261729 | 1 | 8 | 61 | |
| GSE54994 | STEAP2 | 261729 | 17 | 2 | 34 | |
| GSE60625 | STEAP2 | 261729 | 0 | 0 | 11 | |
| GSE74703 | STEAP2 | 261729 | 5 | 1 | 30 | |
| GSE74704 | STEAP2 | 261729 | 9 | 0 | 11 | |
| TCGA | STEAP2 | 261729 | 55 | 5 | 36 |
Total number of gains: 139; Total number of losses: 20; Total Number of normals: 329.
Somatic mutations of STEAP2:
Generating mutation plots.
Highly correlated genes for STEAP2:
Showing top 20/187 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STEAP2 | IGF2BP2 | 0.717969 | 3 | 0 | 3 |
| STEAP2 | TRIP13 | 0.691204 | 3 | 0 | 3 |
| STEAP2 | ADPGK | 0.678597 | 3 | 0 | 3 |
| STEAP2 | SULT1A2 | 0.676403 | 3 | 0 | 3 |
| STEAP2 | EPHB4 | 0.654342 | 3 | 0 | 3 |
| STEAP2 | EME1 | 0.654335 | 3 | 0 | 3 |
| STEAP2 | STEAP1 | 0.648687 | 9 | 0 | 9 |
| STEAP2 | FANCI | 0.647519 | 3 | 0 | 3 |
| STEAP2 | DTL | 0.644242 | 3 | 0 | 3 |
| STEAP2 | CCNB2 | 0.634812 | 3 | 0 | 3 |
| STEAP2 | SLC12A7 | 0.628696 | 4 | 0 | 4 |
| STEAP2 | TNFRSF10B | 0.622826 | 5 | 0 | 4 |
| STEAP2 | KRTCAP3 | 0.620462 | 3 | 0 | 3 |
| STEAP2 | IQCK | 0.618641 | 3 | 0 | 3 |
| STEAP2 | ADAM10 | 0.618477 | 3 | 0 | 3 |
| STEAP2 | ITGA5 | 0.617792 | 4 | 0 | 3 |
| STEAP2 | STC1 | 0.61717 | 5 | 0 | 4 |
| STEAP2 | PCNA | 0.609729 | 3 | 0 | 3 |
| STEAP2 | MET | 0.606517 | 3 | 0 | 3 |
| STEAP2 | PIF1 | 0.606237 | 3 | 0 | 3 |
For details and further investigation, click here
