| Full name: serine/threonine/tyrosine interacting like 1 | Alias Symbol: MK-STYX | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 51657 | HGNC ID: HGNC:18165 | Ensembl Gene: ENSG00000127952 | OMIM ID: 616695 |
| Drug and gene relationship at DGIdb | |||
Expression of STYXL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STYXL1 | 51657 | 232353_s_at | 0.1764 | 0.7765 | |
| GSE20347 | STYXL1 | 51657 | 218321_x_at | -0.1129 | 0.6068 | |
| GSE23400 | STYXL1 | 51657 | 218321_x_at | 0.0450 | 0.5430 | |
| GSE26886 | STYXL1 | 51657 | 232353_s_at | 0.1176 | 0.5054 | |
| GSE29001 | STYXL1 | 51657 | 218321_x_at | -0.4072 | 0.2219 | |
| GSE38129 | STYXL1 | 51657 | 218321_x_at | 0.0953 | 0.5571 | |
| GSE45670 | STYXL1 | 51657 | 232353_s_at | 0.5508 | 0.0132 | |
| GSE53622 | STYXL1 | 51657 | 18519 | 0.2208 | 0.0049 | |
| GSE53624 | STYXL1 | 51657 | 11094 | 0.1175 | 0.1486 | |
| GSE63941 | STYXL1 | 51657 | 232353_s_at | 0.8353 | 0.0496 | |
| GSE77861 | STYXL1 | 51657 | 218321_x_at | 0.0002 | 0.9994 | |
| GSE97050 | STYXL1 | 51657 | A_23_P111635 | 0.5600 | 0.0786 | |
| SRP007169 | STYXL1 | 51657 | RNAseq | -1.2457 | 0.0002 | |
| SRP008496 | STYXL1 | 51657 | RNAseq | -1.1243 | 0.0000 | |
| SRP064894 | STYXL1 | 51657 | RNAseq | 0.3441 | 0.2152 | |
| SRP133303 | STYXL1 | 51657 | RNAseq | 0.4123 | 0.0125 | |
| SRP159526 | STYXL1 | 51657 | RNAseq | -0.2722 | 0.1525 | |
| SRP193095 | STYXL1 | 51657 | RNAseq | -0.0957 | 0.5123 | |
| SRP219564 | STYXL1 | 51657 | RNAseq | 0.5542 | 0.0952 | |
| TCGA | STYXL1 | 51657 | RNAseq | 0.2082 | 0.0075 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by STYXL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STYXL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STYXL1 | 51657 | 14 | 1 | 15 | |
| GSE20123 | STYXL1 | 51657 | 14 | 1 | 15 | |
| GSE43470 | STYXL1 | 51657 | 3 | 2 | 38 | |
| GSE46452 | STYXL1 | 51657 | 12 | 0 | 47 | |
| GSE47630 | STYXL1 | 51657 | 7 | 2 | 31 | |
| GSE54993 | STYXL1 | 51657 | 2 | 7 | 61 | |
| GSE54994 | STYXL1 | 51657 | 14 | 3 | 36 | |
| GSE60625 | STYXL1 | 51657 | 0 | 0 | 11 | |
| GSE74703 | STYXL1 | 51657 | 3 | 1 | 32 | |
| GSE74704 | STYXL1 | 51657 | 8 | 1 | 11 | |
| TCGA | STYXL1 | 51657 | 44 | 5 | 47 |
Total number of gains: 121; Total number of losses: 23; Total Number of normals: 344.
Somatic mutations of STYXL1:
Generating mutation plots.
Highly correlated genes for STYXL1:
Showing top 20/89 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STYXL1 | SPAG1 | 0.663054 | 3 | 0 | 3 |
| STYXL1 | ERAP2 | 0.658838 | 3 | 0 | 3 |
| STYXL1 | TMPRSS13 | 0.654333 | 3 | 0 | 3 |
| STYXL1 | GSDMC | 0.625151 | 4 | 0 | 3 |
| STYXL1 | CPOX | 0.622225 | 3 | 0 | 3 |
| STYXL1 | ATAD3B | 0.607669 | 3 | 0 | 3 |
| STYXL1 | LPAR3 | 0.6069 | 6 | 0 | 5 |
| STYXL1 | TMEM79 | 0.606867 | 3 | 0 | 3 |
| STYXL1 | RNF149 | 0.597699 | 3 | 0 | 3 |
| STYXL1 | TLCD1 | 0.596322 | 4 | 0 | 3 |
| STYXL1 | ARRDC1 | 0.594085 | 4 | 0 | 3 |
| STYXL1 | PNP | 0.591087 | 7 | 0 | 4 |
| STYXL1 | ARPC3 | 0.590325 | 4 | 0 | 3 |
| STYXL1 | C21orf58 | 0.586127 | 3 | 0 | 3 |
| STYXL1 | OXA1L | 0.585918 | 5 | 0 | 3 |
| STYXL1 | FGF11 | 0.584492 | 3 | 0 | 3 |
| STYXL1 | BAIAP2L1 | 0.581561 | 6 | 0 | 3 |
| STYXL1 | HSD17B4 | 0.581401 | 3 | 0 | 3 |
| STYXL1 | TMEM54 | 0.581384 | 4 | 0 | 3 |
| STYXL1 | ADAM17 | 0.577573 | 3 | 0 | 3 |
For details and further investigation, click here
