| Full name: TBC1 domain family member 5 | Alias Symbol: KIAA0210 | ||
| Type: protein-coding gene | Cytoband: 3p24.3 | ||
| Entrez ID: 9779 | HGNC ID: HGNC:19166 | Ensembl Gene: ENSG00000131374 | OMIM ID: 615740 |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D5 | 9779 | 201813_s_at | 0.1194 | 0.7103 | |
| GSE20347 | TBC1D5 | 9779 | 201813_s_at | -0.3441 | 0.0020 | |
| GSE23400 | TBC1D5 | 9779 | 201814_at | -0.1333 | 0.0065 | |
| GSE26886 | TBC1D5 | 9779 | 201814_at | -0.0318 | 0.8836 | |
| GSE29001 | TBC1D5 | 9779 | 201814_at | -0.0215 | 0.9370 | |
| GSE38129 | TBC1D5 | 9779 | 201813_s_at | -0.3017 | 0.0009 | |
| GSE45670 | TBC1D5 | 9779 | 201814_at | -0.4453 | 0.0038 | |
| GSE53622 | TBC1D5 | 9779 | 57615 | -0.4333 | 0.0000 | |
| GSE53624 | TBC1D5 | 9779 | 57615 | -0.2883 | 0.0000 | |
| GSE63941 | TBC1D5 | 9779 | 201813_s_at | 0.2378 | 0.6938 | |
| GSE77861 | TBC1D5 | 9779 | 201813_s_at | 0.0170 | 0.9655 | |
| GSE97050 | TBC1D5 | 9779 | A_23_P355455 | -0.2090 | 0.4116 | |
| SRP007169 | TBC1D5 | 9779 | RNAseq | -0.1096 | 0.7895 | |
| SRP008496 | TBC1D5 | 9779 | RNAseq | 0.0921 | 0.6582 | |
| SRP064894 | TBC1D5 | 9779 | RNAseq | -0.2897 | 0.1622 | |
| SRP133303 | TBC1D5 | 9779 | RNAseq | -0.4377 | 0.0002 | |
| SRP159526 | TBC1D5 | 9779 | RNAseq | -0.3646 | 0.0747 | |
| SRP193095 | TBC1D5 | 9779 | RNAseq | -0.3010 | 0.0001 | |
| SRP219564 | TBC1D5 | 9779 | RNAseq | -0.3398 | 0.3622 | |
| TCGA | TBC1D5 | 9779 | RNAseq | -0.1326 | 0.0043 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBC1D5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D5 | 9779 | 1 | 18 | 11 | |
| GSE20123 | TBC1D5 | 9779 | 1 | 18 | 11 | |
| GSE43470 | TBC1D5 | 9779 | 0 | 20 | 23 | |
| GSE46452 | TBC1D5 | 9779 | 2 | 17 | 40 | |
| GSE47630 | TBC1D5 | 9779 | 1 | 24 | 15 | |
| GSE54993 | TBC1D5 | 9779 | 6 | 1 | 63 | |
| GSE54994 | TBC1D5 | 9779 | 1 | 32 | 20 | |
| GSE60625 | TBC1D5 | 9779 | 5 | 0 | 6 | |
| GSE74703 | TBC1D5 | 9779 | 0 | 17 | 19 | |
| GSE74704 | TBC1D5 | 9779 | 0 | 12 | 8 | |
| TCGA | TBC1D5 | 9779 | 1 | 70 | 25 |
Total number of gains: 18; Total number of losses: 229; Total Number of normals: 241.
Somatic mutations of TBC1D5:
Generating mutation plots.
Highly correlated genes for TBC1D5:
Showing top 20/190 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D5 | GLI3 | 0.764153 | 3 | 0 | 3 |
| TBC1D5 | TTLL1 | 0.723901 | 3 | 0 | 3 |
| TBC1D5 | ERVW-1 | 0.706423 | 3 | 0 | 3 |
| TBC1D5 | POGK | 0.70564 | 3 | 0 | 3 |
| TBC1D5 | API5 | 0.699637 | 3 | 0 | 3 |
| TBC1D5 | GXYLT2 | 0.695816 | 3 | 0 | 3 |
| TBC1D5 | BBX | 0.681478 | 3 | 0 | 3 |
| TBC1D5 | ZNF25 | 0.672577 | 3 | 0 | 3 |
| TBC1D5 | STAG1 | 0.67175 | 3 | 0 | 3 |
| TBC1D5 | SSH1 | 0.670716 | 3 | 0 | 3 |
| TBC1D5 | KIF16B | 0.670427 | 3 | 0 | 3 |
| TBC1D5 | EIF1B | 0.669373 | 4 | 0 | 3 |
| TBC1D5 | JAK1 | 0.655541 | 4 | 0 | 3 |
| TBC1D5 | PSEN1 | 0.652931 | 3 | 0 | 3 |
| TBC1D5 | FNDC3A | 0.652258 | 4 | 0 | 4 |
| TBC1D5 | UBAC1 | 0.646582 | 3 | 0 | 3 |
| TBC1D5 | C5 | 0.644651 | 4 | 0 | 3 |
| TBC1D5 | RGS7BP | 0.638623 | 3 | 0 | 3 |
| TBC1D5 | TPCN1 | 0.637153 | 4 | 0 | 3 |
| TBC1D5 | STX6 | 0.631898 | 3 | 0 | 3 |
For details and further investigation, click here
