| Full name: T-box transcription factor 18 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q14.3 | ||
| Entrez ID: 9096 | HGNC ID: HGNC:11595 | Ensembl Gene: ENSG00000112837 | OMIM ID: 604613 |
| Drug and gene relationship at DGIdb | |||
Expression of TBX18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBX18 | 9096 | 233889_at | -0.0163 | 0.9678 | |
| GSE26886 | TBX18 | 9096 | 233889_at | 0.3755 | 0.0207 | |
| GSE45670 | TBX18 | 9096 | 233889_at | 0.1205 | 0.2477 | |
| GSE53622 | TBX18 | 9096 | 938 | 0.4366 | 0.0706 | |
| GSE53624 | TBX18 | 9096 | 938 | 0.7552 | 0.0000 | |
| GSE63941 | TBX18 | 9096 | 233889_at | 0.3065 | 0.5663 | |
| GSE77861 | TBX18 | 9096 | 233889_at | 0.1314 | 0.3412 | |
| GSE97050 | TBX18 | 9096 | A_23_P134041 | -0.2633 | 0.5541 | |
| SRP064894 | TBX18 | 9096 | RNAseq | 0.6524 | 0.1235 | |
| SRP133303 | TBX18 | 9096 | RNAseq | 0.5405 | 0.2751 | |
| SRP159526 | TBX18 | 9096 | RNAseq | 0.9661 | 0.1544 | |
| SRP219564 | TBX18 | 9096 | RNAseq | 1.3393 | 0.0005 | |
| TCGA | TBX18 | 9096 | RNAseq | 0.7914 | 0.0254 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TBX18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBX18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBX18 | 9096 | 1 | 4 | 25 | |
| GSE20123 | TBX18 | 9096 | 1 | 3 | 26 | |
| GSE43470 | TBX18 | 9096 | 2 | 1 | 40 | |
| GSE46452 | TBX18 | 9096 | 2 | 11 | 46 | |
| GSE47630 | TBX18 | 9096 | 8 | 6 | 26 | |
| GSE54993 | TBX18 | 9096 | 3 | 2 | 65 | |
| GSE54994 | TBX18 | 9096 | 8 | 8 | 37 | |
| GSE60625 | TBX18 | 9096 | 0 | 1 | 10 | |
| GSE74703 | TBX18 | 9096 | 2 | 1 | 33 | |
| GSE74704 | TBX18 | 9096 | 0 | 2 | 18 | |
| TCGA | TBX18 | 9096 | 6 | 21 | 69 |
Total number of gains: 33; Total number of losses: 60; Total Number of normals: 395.
Somatic mutations of TBX18:
Generating mutation plots.
Highly correlated genes for TBX18:
Showing top 20/149 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBX18 | RILPL1 | 0.756874 | 3 | 0 | 3 |
| TBX18 | GPR135 | 0.727937 | 3 | 0 | 3 |
| TBX18 | SF3B4 | 0.706524 | 3 | 0 | 3 |
| TBX18 | KLHL31 | 0.70463 | 3 | 0 | 3 |
| TBX18 | GATAD2B | 0.702992 | 3 | 0 | 3 |
| TBX18 | SSC5D | 0.69609 | 3 | 0 | 3 |
| TBX18 | CRTC2 | 0.692241 | 3 | 0 | 3 |
| TBX18 | MYC | 0.689648 | 3 | 0 | 3 |
| TBX18 | PHC2 | 0.687965 | 3 | 0 | 3 |
| TBX18 | MFGE8 | 0.68586 | 4 | 0 | 3 |
| TBX18 | RAVER1 | 0.683956 | 3 | 0 | 3 |
| TBX18 | NCSTN | 0.682757 | 3 | 0 | 3 |
| TBX18 | PCDH18 | 0.680214 | 3 | 0 | 3 |
| TBX18 | FIBCD1 | 0.673943 | 3 | 0 | 3 |
| TBX18 | ZBTB25 | 0.673414 | 3 | 0 | 3 |
| TBX18 | MAN1A1 | 0.671458 | 3 | 0 | 3 |
| TBX18 | MTMR11 | 0.664616 | 4 | 0 | 4 |
| TBX18 | NENF | 0.658518 | 3 | 0 | 3 |
| TBX18 | RHOBTB2 | 0.653404 | 4 | 0 | 3 |
| TBX18 | XAB2 | 0.652618 | 3 | 0 | 3 |
For details and further investigation, click here
