RIN2

 

Full name: Ras and Rab interactor 2 Alias Symbol: RASSF4
Type: protein-coding gene Cytoband: 20p11.23
Entrez ID: 54453 HGNC ID: HGNC:18750 Ensembl Gene: ENSG00000132669 OMIM ID: 610222
Drug and gene relationship at DGIdb

 

Expression of RIN2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RIN2 54453 209684_at 0.6120 0.1946
GSE20347 RIN2 54453 209684_at 0.4688 0.0137
GSE23400 RIN2 54453 209684_at 0.7441 0.0000
GSE26886 RIN2 54453 209684_at 0.1904 0.4343
GSE29001 RIN2 54453 209684_at 0.6495 0.1088
GSE38129 RIN2 54453 209684_at 0.5761 0.0002
GSE45670 RIN2 54453 209684_at 0.7922 0.0007
GSE53622 RIN2 54453 45952 0.7595 0.0000
GSE53624 RIN2 54453 45952 0.8222 0.0000
GSE63941 RIN2 54453 209684_at -1.5352 0.1617
GSE77861 RIN2 54453 209684_at 0.3680 0.3443
GSE97050 RIN2 54453 A_24_P305570 0.8483 0.0620
SRP007169 RIN2 54453 RNAseq 1.0335 0.0051
SRP008496 RIN2 54453 RNAseq 1.1727 0.0000
SRP064894 RIN2 54453 RNAseq 0.7969 0.0000
SRP133303 RIN2 54453 RNAseq 0.7643 0.0014
SRP159526 RIN2 54453 RNAseq 0.3405 0.3561
SRP193095 RIN2 54453 RNAseq 0.6355 0.0000
SRP219564 RIN2 54453 RNAseq 0.9576 0.0029
TCGA RIN2 54453 RNAseq 0.1308 0.0516

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by RIN2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RIN2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RIN2 54453 13 2 15
GSE20123 RIN2 54453 13 2 15
GSE43470 RIN2 54453 11 1 31
GSE46452 RIN2 54453 27 1 31
GSE47630 RIN2 54453 17 4 19
GSE54993 RIN2 54453 0 15 55
GSE54994 RIN2 54453 26 2 25
GSE60625 RIN2 54453 0 0 11
GSE74703 RIN2 54453 8 1 27
GSE74704 RIN2 54453 7 2 11
TCGA RIN2 54453 43 11 42

Total number of gains: 165; Total number of losses: 41; Total Number of normals: 282.  

 

Somatic mutations of RIN2:

 

Generating mutation plots.

 

Highly correlated genes for RIN2:

 

Showing top 20/847 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RIN2NXN0.761506303
RIN2SDHAF20.758415303
RIN2SPON20.752737303
RIN2ZNF7640.717843303
RIN2VPS350.715037403
RIN2GNG100.712413303
RIN2FAM89A0.71176303
RIN2THAP110.700814404
RIN2KIAA05860.695109303
RIN2THSD10.684731303
RIN2LRRC8C0.683469303
RIN2HEATR60.676648303
RIN2GMCL10.675947303
RIN2CMTM30.675272404
RIN2IRAK20.673731303
RIN2STK350.66467403
RIN2TPM30.663105403
RIN2TMEM1380.662717605
RIN2ZNF4690.660927504
RIN2IFI160.65972512011

For details and further investigation, click here