| Full name: transmembrane 4 L six family member 1 | Alias Symbol: L6 | ||
| Type: protein-coding gene | Cytoband: 3q25.1 | ||
| Entrez ID: 4071 | HGNC ID: HGNC:11853 | Ensembl Gene: ENSG00000169908 | OMIM ID: 191155 |
Expression of TM4SF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TM4SF1 | 4071 | 209386_at | -0.6313 | 0.4905 | |
| GSE20347 | TM4SF1 | 4071 | 209386_at | -0.5402 | 0.0304 | |
| GSE23400 | TM4SF1 | 4071 | 209386_at | -0.4503 | 0.0005 | |
| GSE26886 | TM4SF1 | 4071 | 209386_at | -0.5652 | 0.0318 | |
| GSE29001 | TM4SF1 | 4071 | 209386_at | -0.7932 | 0.0028 | |
| GSE38129 | TM4SF1 | 4071 | 209386_at | -0.2913 | 0.2497 | |
| GSE45670 | TM4SF1 | 4071 | 209386_at | -0.5712 | 0.0340 | |
| GSE53622 | TM4SF1 | 4071 | 89627 | -0.9843 | 0.0000 | |
| GSE53624 | TM4SF1 | 4071 | 89627 | -0.2890 | 0.0008 | |
| GSE63941 | TM4SF1 | 4071 | 209386_at | 0.5074 | 0.7731 | |
| GSE77861 | TM4SF1 | 4071 | 209386_at | -0.2298 | 0.5300 | |
| GSE97050 | TM4SF1 | 4071 | A_33_P3390057 | 0.0905 | 0.8439 | |
| SRP007169 | TM4SF1 | 4071 | RNAseq | -1.3857 | 0.0000 | |
| SRP008496 | TM4SF1 | 4071 | RNAseq | -1.0761 | 0.0008 | |
| SRP064894 | TM4SF1 | 4071 | RNAseq | -0.7129 | 0.0030 | |
| SRP133303 | TM4SF1 | 4071 | RNAseq | -0.5125 | 0.2058 | |
| SRP159526 | TM4SF1 | 4071 | RNAseq | 0.5783 | 0.2002 | |
| SRP193095 | TM4SF1 | 4071 | RNAseq | -0.0225 | 0.9283 | |
| SRP219564 | TM4SF1 | 4071 | RNAseq | -0.3760 | 0.5380 | |
| TCGA | TM4SF1 | 4071 | RNAseq | 0.1623 | 0.0341 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TM4SF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TM4SF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TM4SF1 | 4071 | 22 | 0 | 8 | |
| GSE20123 | TM4SF1 | 4071 | 22 | 0 | 8 | |
| GSE43470 | TM4SF1 | 4071 | 23 | 0 | 20 | |
| GSE46452 | TM4SF1 | 4071 | 18 | 2 | 39 | |
| GSE47630 | TM4SF1 | 4071 | 19 | 3 | 18 | |
| GSE54993 | TM4SF1 | 4071 | 1 | 10 | 59 | |
| GSE54994 | TM4SF1 | 4071 | 37 | 1 | 15 | |
| GSE60625 | TM4SF1 | 4071 | 0 | 6 | 5 | |
| GSE74703 | TM4SF1 | 4071 | 20 | 0 | 16 | |
| GSE74704 | TM4SF1 | 4071 | 15 | 0 | 5 | |
| TCGA | TM4SF1 | 4071 | 71 | 1 | 24 |
Total number of gains: 248; Total number of losses: 23; Total Number of normals: 217.
Somatic mutations of TM4SF1:
Generating mutation plots.
Highly correlated genes for TM4SF1:
Showing top 20/235 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TM4SF1 | ACOT8 | 0.647319 | 3 | 0 | 3 |
| TM4SF1 | USP54 | 0.64396 | 3 | 0 | 3 |
| TM4SF1 | HSD17B10 | 0.622252 | 3 | 0 | 3 |
| TM4SF1 | TCP11L2 | 0.621507 | 3 | 0 | 3 |
| TM4SF1 | STUB1 | 0.61717 | 3 | 0 | 3 |
| TM4SF1 | VPS25 | 0.616842 | 4 | 0 | 3 |
| TM4SF1 | SOX21-AS1 | 0.613756 | 3 | 0 | 3 |
| TM4SF1 | HMGCL | 0.611369 | 5 | 0 | 3 |
| TM4SF1 | PDZRN3 | 0.611194 | 4 | 0 | 3 |
| TM4SF1 | PITHD1 | 0.606627 | 3 | 0 | 3 |
| TM4SF1 | SHROOM3 | 0.600189 | 3 | 0 | 3 |
| TM4SF1 | SERPINB6 | 0.598131 | 6 | 0 | 4 |
| TM4SF1 | PEBP1 | 0.590481 | 3 | 0 | 3 |
| TM4SF1 | TBC1D20 | 0.586878 | 3 | 0 | 3 |
| TM4SF1 | PCTP | 0.585578 | 4 | 0 | 3 |
| TM4SF1 | HCAR3 | 0.583891 | 6 | 0 | 4 |
| TM4SF1 | MEAF6 | 0.583286 | 4 | 0 | 3 |
| TM4SF1 | PRSS8 | 0.583007 | 8 | 0 | 5 |
| TM4SF1 | YPEL3 | 0.582027 | 3 | 0 | 3 |
| TM4SF1 | BECN1 | 0.581825 | 3 | 0 | 3 |
For details and further investigation, click here
