| Full name: transmembrane protein 171 | Alias Symbol: PRP2 | ||
| Type: protein-coding gene | Cytoband: 5q13.2 | ||
| Entrez ID: 134285 | HGNC ID: HGNC:27031 | Ensembl Gene: ENSG00000157111 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM171:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM171 | 134285 | 240770_at | -0.1241 | 0.9082 | |
| GSE26886 | TMEM171 | 134285 | 240770_at | -1.0328 | 0.0016 | |
| GSE45670 | TMEM171 | 134285 | 240770_at | 0.1114 | 0.7544 | |
| GSE53622 | TMEM171 | 134285 | 87809 | -0.6289 | 0.0219 | |
| GSE53624 | TMEM171 | 134285 | 87809 | -1.2556 | 0.0000 | |
| GSE63941 | TMEM171 | 134285 | 240770_at | -0.2362 | 0.5229 | |
| GSE77861 | TMEM171 | 134285 | 1553559_at | -0.1921 | 0.1760 | |
| GSE97050 | TMEM171 | 134285 | A_32_P110390 | -0.0848 | 0.8859 | |
| SRP007169 | TMEM171 | 134285 | RNAseq | -1.7422 | 0.0025 | |
| SRP064894 | TMEM171 | 134285 | RNAseq | -1.1156 | 0.0034 | |
| SRP133303 | TMEM171 | 134285 | RNAseq | -0.7296 | 0.0080 | |
| SRP159526 | TMEM171 | 134285 | RNAseq | -1.4943 | 0.0532 | |
| SRP193095 | TMEM171 | 134285 | RNAseq | -0.9216 | 0.0021 | |
| SRP219564 | TMEM171 | 134285 | RNAseq | -1.3179 | 0.1472 | |
| TCGA | TMEM171 | 134285 | RNAseq | -0.8087 | 0.0014 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by TMEM171 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM171:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM171 | 134285 | 1 | 13 | 16 | |
| GSE20123 | TMEM171 | 134285 | 1 | 13 | 16 | |
| GSE43470 | TMEM171 | 134285 | 1 | 13 | 29 | |
| GSE46452 | TMEM171 | 134285 | 0 | 28 | 31 | |
| GSE47630 | TMEM171 | 134285 | 1 | 19 | 20 | |
| GSE54993 | TMEM171 | 134285 | 8 | 1 | 61 | |
| GSE54994 | TMEM171 | 134285 | 1 | 19 | 33 | |
| GSE60625 | TMEM171 | 134285 | 0 | 0 | 11 | |
| GSE74703 | TMEM171 | 134285 | 1 | 9 | 26 | |
| GSE74704 | TMEM171 | 134285 | 1 | 6 | 13 | |
| TCGA | TMEM171 | 134285 | 4 | 51 | 41 |
Total number of gains: 19; Total number of losses: 172; Total Number of normals: 297.
Somatic mutations of TMEM171:
Generating mutation plots.
Highly correlated genes for TMEM171:
Showing top 20/229 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM171 | RTCA | 0.653869 | 5 | 0 | 5 |
| TMEM171 | LIMK2 | 0.648793 | 3 | 0 | 3 |
| TMEM171 | EPN3 | 0.633678 | 3 | 0 | 3 |
| TMEM171 | PRRG2 | 0.625438 | 6 | 0 | 6 |
| TMEM171 | IL18 | 0.625278 | 5 | 0 | 5 |
| TMEM171 | CYP2D6 | 0.624584 | 4 | 0 | 4 |
| TMEM171 | RNF149 | 0.6186 | 3 | 0 | 3 |
| TMEM171 | KRT83 | 0.613914 | 3 | 0 | 3 |
| TMEM171 | KCNK6 | 0.609206 | 5 | 0 | 4 |
| TMEM171 | EGOT | 0.606308 | 3 | 0 | 3 |
| TMEM171 | ARL14 | 0.603709 | 4 | 0 | 3 |
| TMEM171 | USP43 | 0.600542 | 5 | 0 | 3 |
| TMEM171 | TWF1 | 0.598965 | 5 | 0 | 5 |
| TMEM171 | SGPP2 | 0.597002 | 3 | 0 | 3 |
| TMEM171 | PRRG4 | 0.595905 | 3 | 0 | 3 |
| TMEM171 | C6orf132 | 0.59577 | 7 | 0 | 4 |
| TMEM171 | GCHFR | 0.594966 | 3 | 0 | 3 |
| TMEM171 | GALE | 0.59403 | 6 | 0 | 4 |
| TMEM171 | MREG | 0.593519 | 4 | 0 | 3 |
| TMEM171 | CDK7 | 0.59242 | 5 | 0 | 4 |
For details and further investigation, click here
