| Full name: transmembrane protein 252 | Alias Symbol: MGC34760 | ||
| Type: protein-coding gene | Cytoband: 9q21.11 | ||
| Entrez ID: 169693 | HGNC ID: HGNC:28537 | Ensembl Gene: ENSG00000181778 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM252:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM252 | 169693 | 1553809_a_at | -0.1513 | 0.4781 | |
| GSE26886 | TMEM252 | 169693 | 1553809_a_at | 0.0614 | 0.6240 | |
| GSE45670 | TMEM252 | 169693 | 1553809_a_at | 0.0830 | 0.4072 | |
| GSE53622 | TMEM252 | 169693 | 50791 | -1.9495 | 0.0000 | |
| GSE53624 | TMEM252 | 169693 | 50791 | -1.2253 | 0.0000 | |
| GSE63941 | TMEM252 | 169693 | 1553809_a_at | 0.2166 | 0.1006 | |
| GSE77861 | TMEM252 | 169693 | 1553809_a_at | -0.1591 | 0.1632 | |
| SRP133303 | TMEM252 | 169693 | RNAseq | -2.7499 | 0.0161 | |
| SRP159526 | TMEM252 | 169693 | RNAseq | -2.4074 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by TMEM252 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TMEM252:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM252 | 169693 | 6 | 10 | 14 | |
| GSE20123 | TMEM252 | 169693 | 6 | 11 | 13 | |
| GSE43470 | TMEM252 | 169693 | 6 | 5 | 32 | |
| GSE46452 | TMEM252 | 169693 | 7 | 14 | 38 | |
| GSE47630 | TMEM252 | 169693 | 1 | 19 | 20 | |
| GSE54993 | TMEM252 | 169693 | 5 | 1 | 64 | |
| GSE54994 | TMEM252 | 169693 | 4 | 13 | 36 | |
| GSE60625 | TMEM252 | 169693 | 0 | 0 | 11 | |
| GSE74703 | TMEM252 | 169693 | 5 | 4 | 27 | |
| GSE74704 | TMEM252 | 169693 | 3 | 7 | 10 | |
| TCGA | TMEM252 | 169693 | 18 | 29 | 49 |
Total number of gains: 61; Total number of losses: 113; Total Number of normals: 314.
Somatic mutations of TMEM252:
Generating mutation plots.
Highly correlated genes for TMEM252:
Showing top 20/177 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM252 | APOC3 | 0.693904 | 3 | 0 | 3 |
| TMEM252 | ABCC8 | 0.681529 | 4 | 0 | 3 |
| TMEM252 | MORN3 | 0.672968 | 3 | 0 | 3 |
| TMEM252 | ETFDH | 0.663388 | 3 | 0 | 3 |
| TMEM252 | ZBTB16 | 0.658557 | 3 | 0 | 3 |
| TMEM252 | P2RX1 | 0.655919 | 4 | 0 | 4 |
| TMEM252 | ADAMTSL4 | 0.655511 | 3 | 0 | 3 |
| TMEM252 | MPRIP | 0.654501 | 3 | 0 | 3 |
| TMEM252 | GPX3 | 0.652419 | 3 | 0 | 3 |
| TMEM252 | GPD1L | 0.652129 | 3 | 0 | 3 |
| TMEM252 | PRR26 | 0.645552 | 3 | 0 | 3 |
| TMEM252 | MYL5 | 0.641364 | 4 | 0 | 3 |
| TMEM252 | IL12A-AS1 | 0.639972 | 4 | 0 | 4 |
| TMEM252 | PRDM8 | 0.637436 | 4 | 0 | 3 |
| TMEM252 | SCN2B | 0.636458 | 5 | 0 | 4 |
| TMEM252 | BOK | 0.636412 | 3 | 0 | 3 |
| TMEM252 | UQCRQ | 0.627958 | 4 | 0 | 3 |
| TMEM252 | HMHB1 | 0.627716 | 5 | 0 | 3 |
| TMEM252 | CALCOCO2 | 0.627099 | 3 | 0 | 3 |
| TMEM252 | HIPK3 | 0.626607 | 3 | 0 | 3 |
For details and further investigation, click here
