| Full name: transmembrane protein 150B | Alias Symbol: TTN2|DRAM3 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 284417 | HGNC ID: HGNC:34415 | Ensembl Gene: ENSG00000180061 | OMIM ID: 617291 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM150B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM150B | 284417 | 1570225_at | -0.1000 | 0.7111 | |
| GSE26886 | TMEM150B | 284417 | 1570225_at | 0.0759 | 0.4102 | |
| GSE45670 | TMEM150B | 284417 | 1570225_at | 0.1439 | 0.1430 | |
| GSE53622 | TMEM150B | 284417 | 10258 | 0.6889 | 0.0002 | |
| GSE53624 | TMEM150B | 284417 | 16976 | 0.6599 | 0.0000 | |
| GSE63941 | TMEM150B | 284417 | 1570225_at | 0.0319 | 0.8596 | |
| GSE77861 | TMEM150B | 284417 | 1570225_at | -0.1376 | 0.1998 | |
| GSE97050 | TMEM150B | 284417 | A_33_P3401008 | 0.1308 | 0.8548 | |
| SRP219564 | TMEM150B | 284417 | RNAseq | 1.5256 | 0.0275 | |
| TCGA | TMEM150B | 284417 | RNAseq | 0.5575 | 0.2596 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TMEM150B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM150B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM150B | 284417 | 3 | 4 | 23 | |
| GSE20123 | TMEM150B | 284417 | 3 | 3 | 24 | |
| GSE43470 | TMEM150B | 284417 | 3 | 11 | 29 | |
| GSE46452 | TMEM150B | 284417 | 45 | 1 | 13 | |
| GSE47630 | TMEM150B | 284417 | 8 | 6 | 26 | |
| GSE54993 | TMEM150B | 284417 | 17 | 4 | 49 | |
| GSE54994 | TMEM150B | 284417 | 4 | 13 | 36 | |
| GSE60625 | TMEM150B | 284417 | 9 | 0 | 2 | |
| GSE74703 | TMEM150B | 284417 | 3 | 7 | 26 | |
| GSE74704 | TMEM150B | 284417 | 3 | 1 | 16 | |
| TCGA | TMEM150B | 284417 | 20 | 14 | 62 |
Total number of gains: 118; Total number of losses: 64; Total Number of normals: 306.
Somatic mutations of TMEM150B:
Generating mutation plots.
Highly correlated genes for TMEM150B:
Showing top 20/86 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM150B | SLC7A7 | 0.772289 | 3 | 0 | 3 |
| TMEM150B | SPI1 | 0.745189 | 3 | 0 | 3 |
| TMEM150B | FPR3 | 0.735594 | 3 | 0 | 3 |
| TMEM150B | LILRB4 | 0.704285 | 3 | 0 | 3 |
| TMEM150B | TRANK1 | 0.703864 | 3 | 0 | 3 |
| TMEM150B | KLRD1 | 0.689223 | 4 | 0 | 4 |
| TMEM150B | MYO7A | 0.681194 | 3 | 0 | 3 |
| TMEM150B | SPATA13 | 0.664138 | 3 | 0 | 3 |
| TMEM150B | LRRC25 | 0.659186 | 4 | 0 | 3 |
| TMEM150B | PDCD1LG2 | 0.652848 | 3 | 0 | 3 |
| TMEM150B | ATP8B4 | 0.648242 | 3 | 0 | 3 |
| TMEM150B | RASGRP3 | 0.643321 | 4 | 0 | 3 |
| TMEM150B | SLA | 0.641591 | 3 | 0 | 3 |
| TMEM150B | GLB1 | 0.639844 | 3 | 0 | 3 |
| TMEM150B | SIGLEC12 | 0.635306 | 3 | 0 | 3 |
| TMEM150B | TAGAP | 0.633537 | 3 | 0 | 3 |
| TMEM150B | DOK2 | 0.630891 | 4 | 0 | 3 |
| TMEM150B | SLAMF8 | 0.626959 | 4 | 0 | 3 |
| TMEM150B | IL2RB | 0.623317 | 3 | 0 | 3 |
| TMEM150B | CCL3 | 0.622673 | 3 | 0 | 3 |
For details and further investigation, click here
