| Full name: transient receptor potential cation channel subfamily C member 7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 57113 | HGNC ID: HGNC:20754 | Ensembl Gene: ENSG00000069018 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TRPC7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRPC7 | 57113 | 208589_at | 0.1423 | 0.4570 | |
| GSE20347 | TRPC7 | 57113 | 208589_at | -0.0491 | 0.4320 | |
| GSE23400 | TRPC7 | 57113 | 208589_at | -0.0709 | 0.1019 | |
| GSE26886 | TRPC7 | 57113 | 208589_at | 0.1486 | 0.1611 | |
| GSE29001 | TRPC7 | 57113 | 208589_at | -0.0861 | 0.5096 | |
| GSE38129 | TRPC7 | 57113 | 208589_at | -0.0904 | 0.0653 | |
| GSE45670 | TRPC7 | 57113 | 208589_at | 0.0087 | 0.9421 | |
| GSE53622 | TRPC7 | 57113 | 109714 | 0.3810 | 0.0015 | |
| GSE53624 | TRPC7 | 57113 | 109714 | 0.5026 | 0.0000 | |
| GSE63941 | TRPC7 | 57113 | 208589_at | -0.0436 | 0.7970 | |
| GSE77861 | TRPC7 | 57113 | 208589_at | -0.0429 | 0.6495 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRPC7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRPC7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRPC7 | 57113 | 3 | 11 | 16 | |
| GSE20123 | TRPC7 | 57113 | 4 | 11 | 15 | |
| GSE43470 | TRPC7 | 57113 | 4 | 6 | 33 | |
| GSE46452 | TRPC7 | 57113 | 0 | 27 | 32 | |
| GSE47630 | TRPC7 | 57113 | 0 | 21 | 19 | |
| GSE54993 | TRPC7 | 57113 | 9 | 1 | 60 | |
| GSE54994 | TRPC7 | 57113 | 3 | 13 | 37 | |
| GSE60625 | TRPC7 | 57113 | 0 | 0 | 11 | |
| GSE74703 | TRPC7 | 57113 | 3 | 5 | 28 | |
| GSE74704 | TRPC7 | 57113 | 3 | 5 | 12 | |
| TCGA | TRPC7 | 57113 | 4 | 36 | 56 |
Total number of gains: 33; Total number of losses: 136; Total Number of normals: 319.
Somatic mutations of TRPC7:
Generating mutation plots.
Highly correlated genes for TRPC7:
Showing top 20/255 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRPC7 | LCT | 0.69619 | 3 | 0 | 3 |
| TRPC7 | COL2A1 | 0.66134 | 3 | 0 | 3 |
| TRPC7 | HAPLN1 | 0.646035 | 3 | 0 | 3 |
| TRPC7 | CR1 | 0.644781 | 3 | 0 | 3 |
| TRPC7 | KDM6B | 0.640003 | 3 | 0 | 3 |
| TRPC7 | TCP10L | 0.636396 | 4 | 0 | 4 |
| TRPC7 | SPINK2 | 0.635443 | 3 | 0 | 3 |
| TRPC7 | PDC | 0.635217 | 4 | 0 | 4 |
| TRPC7 | IL17A | 0.633685 | 4 | 0 | 3 |
| TRPC7 | MUC5AC | 0.630792 | 4 | 0 | 3 |
| TRPC7 | CITED1 | 0.622256 | 3 | 0 | 3 |
| TRPC7 | HNF4G | 0.622171 | 3 | 0 | 3 |
| TRPC7 | NOL4 | 0.621532 | 4 | 0 | 3 |
| TRPC7 | CYP19A1 | 0.619354 | 4 | 0 | 4 |
| TRPC7 | SIRT3 | 0.619065 | 3 | 0 | 3 |
| TRPC7 | HLA-DOA | 0.61833 | 4 | 0 | 3 |
| TRPC7 | TUB | 0.617769 | 4 | 0 | 4 |
| TRPC7 | UGT2A3 | 0.616792 | 3 | 0 | 3 |
| TRPC7 | C6 | 0.613629 | 4 | 0 | 3 |
| TRPC7 | SAG | 0.613393 | 5 | 0 | 5 |
For details and further investigation, click here
