| Full name: UBX domain protein 8 | Alias Symbol: D8S2298E|REP8 | ||
| Type: protein-coding gene | Cytoband: 8p12 | ||
| Entrez ID: 7993 | HGNC ID: HGNC:30307 | Ensembl Gene: ENSG00000104691 | OMIM ID: 602155 |
| Drug and gene relationship at DGIdb | |||
Expression of UBXN8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBXN8 | 7993 | 215983_s_at | -0.1135 | 0.8697 | |
| GSE20347 | UBXN8 | 7993 | 215983_s_at | -0.0601 | 0.7447 | |
| GSE23400 | UBXN8 | 7993 | 215983_s_at | 0.0617 | 0.2964 | |
| GSE26886 | UBXN8 | 7993 | 215983_s_at | -0.4850 | 0.0297 | |
| GSE29001 | UBXN8 | 7993 | 215983_s_at | 0.0063 | 0.9885 | |
| GSE38129 | UBXN8 | 7993 | 215983_s_at | -0.0251 | 0.9001 | |
| GSE45670 | UBXN8 | 7993 | 215983_s_at | 0.2785 | 0.0622 | |
| GSE53622 | UBXN8 | 7993 | 25130 | -0.1666 | 0.1208 | |
| GSE53624 | UBXN8 | 7993 | 47392 | -0.2837 | 0.0009 | |
| GSE63941 | UBXN8 | 7993 | 215983_s_at | -1.4037 | 0.0122 | |
| GSE77861 | UBXN8 | 7993 | 215983_s_at | -0.0744 | 0.8565 | |
| GSE97050 | UBXN8 | 7993 | A_23_P157465 | 0.1914 | 0.4363 | |
| SRP007169 | UBXN8 | 7993 | RNAseq | 0.3240 | 0.6164 | |
| SRP064894 | UBXN8 | 7993 | RNAseq | 0.2924 | 0.1391 | |
| SRP133303 | UBXN8 | 7993 | RNAseq | -0.6569 | 0.0039 | |
| SRP159526 | UBXN8 | 7993 | RNAseq | -0.3068 | 0.3929 | |
| SRP193095 | UBXN8 | 7993 | RNAseq | -0.3191 | 0.0644 | |
| SRP219564 | UBXN8 | 7993 | RNAseq | -0.2244 | 0.4787 | |
| TCGA | UBXN8 | 7993 | RNAseq | -0.3651 | 0.0009 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UBXN8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBXN8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBXN8 | 7993 | 4 | 11 | 15 | |
| GSE20123 | UBXN8 | 7993 | 4 | 11 | 15 | |
| GSE43470 | UBXN8 | 7993 | 4 | 7 | 32 | |
| GSE46452 | UBXN8 | 7993 | 13 | 13 | 33 | |
| GSE47630 | UBXN8 | 7993 | 10 | 8 | 22 | |
| GSE54993 | UBXN8 | 7993 | 2 | 15 | 53 | |
| GSE54994 | UBXN8 | 7993 | 11 | 15 | 27 | |
| GSE60625 | UBXN8 | 7993 | 3 | 0 | 8 | |
| GSE74703 | UBXN8 | 7993 | 4 | 6 | 26 | |
| GSE74704 | UBXN8 | 7993 | 3 | 7 | 10 | |
| TCGA | UBXN8 | 7993 | 19 | 40 | 37 |
Total number of gains: 77; Total number of losses: 133; Total Number of normals: 278.
Somatic mutations of UBXN8:
Generating mutation plots.
Highly correlated genes for UBXN8:
Showing top 20/73 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBXN8 | TXNDC17 | 0.704684 | 3 | 0 | 3 |
| UBXN8 | KCNJ2 | 0.655718 | 3 | 0 | 3 |
| UBXN8 | CDC23 | 0.640351 | 4 | 0 | 3 |
| UBXN8 | DSTYK | 0.638144 | 3 | 0 | 3 |
| UBXN8 | CTBP1 | 0.634836 | 3 | 0 | 3 |
| UBXN8 | DLEU1 | 0.63137 | 4 | 0 | 4 |
| UBXN8 | MYL12B | 0.629888 | 4 | 0 | 3 |
| UBXN8 | PPP3CC | 0.618758 | 6 | 0 | 5 |
| UBXN8 | LARS2 | 0.615038 | 3 | 0 | 3 |
| UBXN8 | ACO1 | 0.612639 | 3 | 0 | 3 |
| UBXN8 | BAG4 | 0.61255 | 4 | 0 | 3 |
| UBXN8 | MRPL39 | 0.601771 | 4 | 0 | 3 |
| UBXN8 | RAB6A | 0.597979 | 3 | 0 | 3 |
| UBXN8 | CLIP1 | 0.597728 | 3 | 0 | 3 |
| UBXN8 | LACC1 | 0.594515 | 3 | 0 | 3 |
| UBXN8 | RRM1 | 0.593886 | 3 | 0 | 3 |
| UBXN8 | HOOK3 | 0.58937 | 4 | 0 | 4 |
| UBXN8 | SRP72 | 0.587474 | 3 | 0 | 3 |
| UBXN8 | PCSK5 | 0.587456 | 3 | 0 | 3 |
| UBXN8 | DUSP11 | 0.586983 | 5 | 0 | 3 |
For details and further investigation, click here
