UCA1

 

Full name: urothelial cancer associated 1 Alias Symbol: LINC00178|CUDR|UCAT1|onco-lncRNA-36
Type: non-coding RNA Cytoband: 19p13.12
Entrez ID: 652995 HGNC ID: HGNC:37126 Ensembl Gene: ENSG00000214049 OMIM ID: 617500
Drug and gene relationship at DGIdb

 

Expression of UCA1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UCA1 652995 227919_at -0.5322 0.3093
GSE26886 UCA1 652995 227919_at -1.5016 0.0000
GSE45670 UCA1 652995 227919_at -0.0219 0.9496
GSE53622 UCA1 652995 148078 -0.5326 0.0415
GSE53624 UCA1 652995 78977 0.0862 0.4819
GSE63941 UCA1 652995 227919_at 3.4086 0.0863
GSE77861 UCA1 652995 227919_at -0.2775 0.0834
SRP007169 UCA1 652995 RNAseq -0.6086 0.5947
SRP064894 UCA1 652995 RNAseq -1.8923 0.0000
SRP133303 UCA1 652995 RNAseq -0.3160 0.1888
SRP159526 UCA1 652995 RNAseq -2.0095 0.0000
SRP219564 UCA1 652995 RNAseq -0.2180 0.8061
TCGA UCA1 652995 RNAseq 0.8955 0.0856

Upregulated datasets: 0; Downregulated datasets: 3.  


 

Survival by UCA1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of UCA1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UCA1 652995 4 2 24
GSE20123 UCA1 652995 3 1 26
GSE43470 UCA1 652995 2 5 36
GSE46452 UCA1 652995 47 1 11
GSE47630 UCA1 652995 4 8 28
GSE54993 UCA1 652995 15 4 51
GSE54994 UCA1 652995 6 14 33
GSE60625 UCA1 652995 9 0 2
GSE74703 UCA1 652995 2 4 30
GSE74704 UCA1 652995 0 1 19
TCGA UCA1 652995 18 12 66

Total number of gains: 110; Total number of losses: 52; Total Number of normals: 326.  


 

Somatic mutations of UCA1:

 

Generating mutation plots.

 

Highly correlated genes for UCA1:

 

Showing top 20/466 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UCA1STAU20.724018303
UCA1EVPLL0.709121303
UCA1EP300-AS10.70713303
UCA1COBLL10.706379303
UCA1MAPT0.704952303
UCA1GALNT120.699764303
UCA1TMEM1540.697485404
UCA1GUF10.693667303
UCA1MPZL30.693043605
UCA1KCNK70.692148303
UCA1GBP60.690487303
UCA1ORMDL20.687774303
UCA1ARHGAP320.6863505
UCA1CD2AP0.682929303
UCA1STXBP50.677024404
UCA1CAB39L0.676753303
UCA1MAGI30.671408303
UCA1TMEM184A0.670461303
UCA1STRN0.670162505
UCA1ALAD0.666977303

For details and further investigation, click here