| Full name: sulfatase 2 | Alias Symbol: KIAA1247|HSULF-2|SULF-2 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 55959 | HGNC ID: HGNC:20392 | Ensembl Gene: ENSG00000196562 | OMIM ID: 610013 |
| Drug and gene relationship at DGIdb | |||
Expression of SULF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SULF2 | 55959 | 224724_at | 0.7045 | 0.1214 | |
| GSE26886 | SULF2 | 55959 | 224724_at | 0.4222 | 0.3626 | |
| GSE45670 | SULF2 | 55959 | 224724_at | 0.2479 | 0.3841 | |
| GSE53622 | SULF2 | 55959 | 88506 | 0.4950 | 0.0001 | |
| GSE53624 | SULF2 | 55959 | 88506 | 0.6628 | 0.0000 | |
| GSE63941 | SULF2 | 55959 | 224724_at | -2.5487 | 0.0624 | |
| GSE77861 | SULF2 | 55959 | 224724_at | 0.2250 | 0.6475 | |
| GSE97050 | SULF2 | 55959 | A_23_P154605 | 0.4988 | 0.1695 | |
| SRP007169 | SULF2 | 55959 | RNAseq | 0.1495 | 0.8076 | |
| SRP008496 | SULF2 | 55959 | RNAseq | 0.7170 | 0.1250 | |
| SRP064894 | SULF2 | 55959 | RNAseq | 0.9242 | 0.0012 | |
| SRP133303 | SULF2 | 55959 | RNAseq | 1.0921 | 0.0016 | |
| SRP159526 | SULF2 | 55959 | RNAseq | 0.6937 | 0.1491 | |
| SRP193095 | SULF2 | 55959 | RNAseq | 0.3802 | 0.1278 | |
| SRP219564 | SULF2 | 55959 | RNAseq | 0.6975 | 0.0833 | |
| TCGA | SULF2 | 55959 | RNAseq | 0.4779 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SULF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SULF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SULF2 | 55959 | 15 | 2 | 13 | |
| GSE20123 | SULF2 | 55959 | 15 | 2 | 13 | |
| GSE43470 | SULF2 | 55959 | 12 | 1 | 30 | |
| GSE46452 | SULF2 | 55959 | 29 | 0 | 30 | |
| GSE47630 | SULF2 | 55959 | 24 | 1 | 15 | |
| GSE54993 | SULF2 | 55959 | 0 | 18 | 52 | |
| GSE54994 | SULF2 | 55959 | 26 | 0 | 27 | |
| GSE60625 | SULF2 | 55959 | 0 | 0 | 11 | |
| GSE74703 | SULF2 | 55959 | 10 | 1 | 25 | |
| GSE74704 | SULF2 | 55959 | 11 | 0 | 9 | |
| TCGA | SULF2 | 55959 | 45 | 3 | 48 |
Total number of gains: 187; Total number of losses: 28; Total Number of normals: 273.
Somatic mutations of SULF2:
Generating mutation plots.
Highly correlated genes for SULF2:
Showing top 20/126 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SULF2 | UTP15 | 0.718483 | 3 | 0 | 3 |
| SULF2 | COPS8 | 0.705103 | 3 | 0 | 3 |
| SULF2 | PTPN1 | 0.69199 | 3 | 0 | 3 |
| SULF2 | MAK16 | 0.65277 | 3 | 0 | 3 |
| SULF2 | ATP13A3 | 0.632642 | 3 | 0 | 3 |
| SULF2 | INTS1 | 0.632136 | 3 | 0 | 3 |
| SULF2 | TNPO1 | 0.629613 | 3 | 0 | 3 |
| SULF2 | GUCY1A2 | 0.628906 | 3 | 0 | 3 |
| SULF2 | CBLB | 0.616914 | 3 | 0 | 3 |
| SULF2 | DBR1 | 0.612519 | 3 | 0 | 3 |
| SULF2 | MPP6 | 0.612146 | 4 | 0 | 3 |
| SULF2 | VAC14 | 0.609972 | 4 | 0 | 3 |
| SULF2 | C17orf75 | 0.608225 | 3 | 0 | 3 |
| SULF2 | NAV1 | 0.608179 | 6 | 0 | 5 |
| SULF2 | PLAU | 0.608122 | 5 | 0 | 3 |
| SULF2 | ERF | 0.602815 | 3 | 0 | 3 |
| SULF2 | AGPS | 0.5999 | 4 | 0 | 4 |
| SULF2 | UBE2E3 | 0.599764 | 4 | 0 | 3 |
| SULF2 | FAM20C | 0.596882 | 3 | 0 | 3 |
| SULF2 | PDE7A | 0.594664 | 5 | 0 | 4 |
For details and further investigation, click here
