| Full name: acyl-CoA dehydrogenase family member 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q25 | ||
| Entrez ID: 27034 | HGNC ID: HGNC:87 | Ensembl Gene: ENSG00000151498 | OMIM ID: 604773 |
| Drug and gene relationship at DGIdb | |||
Expression of ACAD8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACAD8 | 27034 | 221669_s_at | -0.4361 | 0.2362 | |
| GSE20347 | ACAD8 | 27034 | 221669_s_at | -0.5708 | 0.0001 | |
| GSE23400 | ACAD8 | 27034 | 221669_s_at | -0.2610 | 0.0023 | |
| GSE26886 | ACAD8 | 27034 | 221669_s_at | -2.1300 | 0.0000 | |
| GSE29001 | ACAD8 | 27034 | 221669_s_at | -0.3183 | 0.2079 | |
| GSE38129 | ACAD8 | 27034 | 221669_s_at | -0.5067 | 0.0006 | |
| GSE45670 | ACAD8 | 27034 | 221669_s_at | -0.2209 | 0.2495 | |
| GSE53622 | ACAD8 | 27034 | 14831 | -0.1468 | 0.3690 | |
| GSE53624 | ACAD8 | 27034 | 14831 | -0.2866 | 0.0189 | |
| GSE63941 | ACAD8 | 27034 | 221669_s_at | -1.2608 | 0.0230 | |
| GSE77861 | ACAD8 | 27034 | 221669_s_at | -0.6703 | 0.0052 | |
| GSE97050 | ACAD8 | 27034 | A_23_P47426 | -0.0039 | 0.9915 | |
| SRP007169 | ACAD8 | 27034 | RNAseq | -1.5696 | 0.0064 | |
| SRP008496 | ACAD8 | 27034 | RNAseq | -1.5960 | 0.0000 | |
| SRP064894 | ACAD8 | 27034 | RNAseq | -0.5279 | 0.0008 | |
| SRP133303 | ACAD8 | 27034 | RNAseq | -0.9492 | 0.0000 | |
| SRP159526 | ACAD8 | 27034 | RNAseq | -0.7610 | 0.0001 | |
| SRP193095 | ACAD8 | 27034 | RNAseq | -0.9842 | 0.0000 | |
| SRP219564 | ACAD8 | 27034 | RNAseq | -0.6215 | 0.0508 | |
| TCGA | ACAD8 | 27034 | RNAseq | -0.3927 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ACAD8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACAD8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACAD8 | 27034 | 0 | 15 | 15 | |
| GSE20123 | ACAD8 | 27034 | 0 | 15 | 15 | |
| GSE43470 | ACAD8 | 27034 | 2 | 8 | 33 | |
| GSE46452 | ACAD8 | 27034 | 3 | 26 | 30 | |
| GSE47630 | ACAD8 | 27034 | 2 | 19 | 19 | |
| GSE54993 | ACAD8 | 27034 | 10 | 0 | 60 | |
| GSE54994 | ACAD8 | 27034 | 5 | 18 | 30 | |
| GSE60625 | ACAD8 | 27034 | 0 | 3 | 8 | |
| GSE74703 | ACAD8 | 27034 | 1 | 5 | 30 | |
| GSE74704 | ACAD8 | 27034 | 0 | 11 | 9 | |
| TCGA | ACAD8 | 27034 | 6 | 49 | 41 |
Total number of gains: 29; Total number of losses: 169; Total Number of normals: 290.
Somatic mutations of ACAD8:
Generating mutation plots.
Highly correlated genes for ACAD8:
Showing top 20/746 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACAD8 | RASSF5 | 0.728176 | 3 | 0 | 3 |
| ACAD8 | MCEE | 0.707315 | 4 | 0 | 4 |
| ACAD8 | CXCL17 | 0.707213 | 4 | 0 | 3 |
| ACAD8 | SPATA18 | 0.694115 | 3 | 0 | 3 |
| ACAD8 | SLC18B1 | 0.691889 | 4 | 0 | 3 |
| ACAD8 | PLRG1 | 0.691594 | 3 | 0 | 3 |
| ACAD8 | FAM3D | 0.685478 | 4 | 0 | 4 |
| ACAD8 | KLHDC8B | 0.681062 | 5 | 0 | 4 |
| ACAD8 | CAPN14 | 0.678946 | 4 | 0 | 4 |
| ACAD8 | ZMAT2 | 0.677977 | 4 | 0 | 3 |
| ACAD8 | KRT78 | 0.677774 | 4 | 0 | 4 |
| ACAD8 | GID4 | 0.677079 | 4 | 0 | 3 |
| ACAD8 | ZNF879 | 0.676949 | 3 | 0 | 3 |
| ACAD8 | CIPC | 0.676846 | 4 | 0 | 3 |
| ACAD8 | TMEM50A | 0.675827 | 4 | 0 | 3 |
| ACAD8 | PDIK1L | 0.666982 | 4 | 0 | 3 |
| ACAD8 | ADIPOR1 | 0.666779 | 4 | 0 | 3 |
| ACAD8 | FAM3B | 0.66673 | 4 | 0 | 3 |
| ACAD8 | RBM20 | 0.66439 | 5 | 0 | 4 |
| ACAD8 | FAM221A | 0.662491 | 4 | 0 | 3 |
For details and further investigation, click here
