| Full name: adiponectin receptor 2 | Alias Symbol: PAQR2|ACDCR2 | ||
| Type: protein-coding gene | Cytoband: 12p13.33 | ||
| Entrez ID: 79602 | HGNC ID: HGNC:24041 | Ensembl Gene: ENSG00000006831 | OMIM ID: 607946 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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ADIPOR2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04152 | AMPK signaling pathway | |
| hsa04211 | Longevity regulating pathway - mammal | |
| hsa04920 | Adipocytokine signaling pathway | |
| hsa04932 | Non-alcoholic fatty liver disease (NAFLD) |
Expression of ADIPOR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADIPOR2 | 79602 | 201346_at | 0.1483 | 0.7747 | |
| GSE20347 | ADIPOR2 | 79602 | 201346_at | -0.3207 | 0.0316 | |
| GSE23400 | ADIPOR2 | 79602 | 201346_at | -0.2659 | 0.0008 | |
| GSE26886 | ADIPOR2 | 79602 | 201346_at | -1.2341 | 0.0000 | |
| GSE29001 | ADIPOR2 | 79602 | 201346_at | -0.2676 | 0.3152 | |
| GSE38129 | ADIPOR2 | 79602 | 201346_at | -0.2970 | 0.0291 | |
| GSE45670 | ADIPOR2 | 79602 | 201346_at | -0.2080 | 0.3297 | |
| GSE53622 | ADIPOR2 | 79602 | 81584 | -0.3549 | 0.0000 | |
| GSE53624 | ADIPOR2 | 79602 | 29243 | -0.5126 | 0.0000 | |
| GSE63941 | ADIPOR2 | 79602 | 201346_at | 1.0655 | 0.0102 | |
| GSE77861 | ADIPOR2 | 79602 | 201346_at | -0.0919 | 0.8212 | |
| GSE97050 | ADIPOR2 | 79602 | A_23_P48121 | -0.0987 | 0.7522 | |
| SRP007169 | ADIPOR2 | 79602 | RNAseq | -0.3736 | 0.5488 | |
| SRP008496 | ADIPOR2 | 79602 | RNAseq | -0.3894 | 0.3294 | |
| SRP064894 | ADIPOR2 | 79602 | RNAseq | -1.2770 | 0.0000 | |
| SRP133303 | ADIPOR2 | 79602 | RNAseq | -0.1915 | 0.4190 | |
| SRP159526 | ADIPOR2 | 79602 | RNAseq | -0.4452 | 0.0050 | |
| SRP193095 | ADIPOR2 | 79602 | RNAseq | -1.1061 | 0.0000 | |
| SRP219564 | ADIPOR2 | 79602 | RNAseq | -0.7773 | 0.0341 | |
| TCGA | ADIPOR2 | 79602 | RNAseq | -0.1456 | 0.0011 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by ADIPOR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADIPOR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADIPOR2 | 79602 | 7 | 4 | 19 | |
| GSE20123 | ADIPOR2 | 79602 | 7 | 4 | 19 | |
| GSE43470 | ADIPOR2 | 79602 | 11 | 3 | 29 | |
| GSE46452 | ADIPOR2 | 79602 | 10 | 1 | 48 | |
| GSE47630 | ADIPOR2 | 79602 | 12 | 2 | 26 | |
| GSE54993 | ADIPOR2 | 79602 | 1 | 10 | 59 | |
| GSE54994 | ADIPOR2 | 79602 | 10 | 2 | 41 | |
| GSE60625 | ADIPOR2 | 79602 | 0 | 1 | 10 | |
| GSE74703 | ADIPOR2 | 79602 | 10 | 2 | 24 | |
| GSE74704 | ADIPOR2 | 79602 | 4 | 2 | 14 | |
| TCGA | ADIPOR2 | 79602 | 38 | 8 | 50 |
Total number of gains: 110; Total number of losses: 39; Total Number of normals: 339.
Somatic mutations of ADIPOR2:
Generating mutation plots.
Highly correlated genes for ADIPOR2:
Showing top 20/307 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADIPOR2 | KDM6A | 0.646029 | 5 | 0 | 4 |
| ADIPOR2 | EPS15 | 0.630275 | 4 | 0 | 4 |
| ADIPOR2 | KRT18 | 0.629353 | 4 | 0 | 4 |
| ADIPOR2 | CMAS | 0.627521 | 12 | 0 | 10 |
| ADIPOR2 | MED28 | 0.621413 | 3 | 0 | 3 |
| ADIPOR2 | WWC1 | 0.612886 | 9 | 0 | 8 |
| ADIPOR2 | TAB3 | 0.609172 | 6 | 0 | 4 |
| ADIPOR2 | DMKN | 0.607395 | 4 | 0 | 3 |
| ADIPOR2 | MECOM | 0.604906 | 6 | 0 | 5 |
| ADIPOR2 | MRPS7 | 0.602185 | 5 | 0 | 4 |
| ADIPOR2 | SYTL1 | 0.599589 | 5 | 0 | 3 |
| ADIPOR2 | GRHL1 | 0.598926 | 6 | 0 | 5 |
| ADIPOR2 | FAM135A | 0.598178 | 6 | 0 | 5 |
| ADIPOR2 | SNRNP40 | 0.597974 | 4 | 0 | 3 |
| ADIPOR2 | ZNF384 | 0.5973 | 4 | 0 | 3 |
| ADIPOR2 | DUOXA1 | 0.596963 | 4 | 0 | 3 |
| ADIPOR2 | STK38 | 0.596342 | 4 | 0 | 3 |
| ADIPOR2 | ADIPOR1 | 0.596341 | 9 | 0 | 7 |
| ADIPOR2 | SIAH2 | 0.595733 | 9 | 0 | 5 |
| ADIPOR2 | LNX1 | 0.592067 | 5 | 0 | 3 |
For details and further investigation, click here
