Full name: adenosine kinase	Alias Symbol: AK
Type: protein-coding gene	Cytoband: 10q22.2
Entrez ID: 132	HGNC ID: HGNC:257	Ensembl Gene: ENSG00000156110	OMIM ID: 102750
Drug and gene relationship at DGIdb

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Expression of ADK:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	ADK	132	204119_s_at	-0.3198	0.5911	Show
GSE20347	ADK	132	204119_s_at	-0.7251	0.0001	Show
GSE23400	ADK	132	204119_s_at	-0.1891	0.0590	Show
GSE26886	ADK	132	204119_s_at	-0.9966	0.0505	Show
GSE29001	ADK	132	204119_s_at	-0.8326	0.0415	Show
GSE38129	ADK	132	204119_s_at	-0.2097	0.3469	Show
GSE45670	ADK	132	204119_s_at	-0.2409	0.1359	Show
GSE53622	ADK	132	7690	-0.3438	0.0006	Show
GSE53624	ADK	132	7690	-0.4209	0.0000	Show
GSE63941	ADK	132	204119_s_at	2.0016	0.0004	Show
GSE77861	ADK	132	204119_s_at	-0.6596	0.0309	Show
GSE97050	ADK	132	A_23_P112596	0.3302	0.4058	Show
SRP007169	ADK	132	RNAseq	-1.8928	0.0002	Show
SRP008496	ADK	132	RNAseq	-1.5499	0.0000	Show
SRP064894	ADK	132	RNAseq	-0.8526	0.0000	Show
SRP133303	ADK	132	RNAseq	-0.0107	0.9536	Show
SRP159526	ADK	132	RNAseq	-0.6390	0.1633	Show
SRP193095	ADK	132	RNAseq	-0.9250	0.0000	Show
SRP219564	ADK	132	RNAseq	-0.8023	0.0545	Show
TCGA	ADK	132	RNAseq	0.2694	0.0000	Show

Upregulated datasets: 1; Downregulated datasets: 2.  Download Data

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Survival by ADK expression:

 

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Copy number change of ADK:

 

Dataset	Gene	EntrezID	Gain	Loss	Normal	Detail
GSE15526	ADK	132	3	5	22	Show
GSE20123	ADK	132	3	4	23	Show
GSE43470	ADK	132	2	8	33	Show
GSE46452	ADK	132	0	11	48	Show
GSE47630	ADK	132	2	14	24	Show
GSE54993	ADK	132	7	0	63	Show
GSE54994	ADK	132	2	10	41	Show
GSE60625	ADK	132	0	0	11	Show
GSE74703	ADK	132	2	5	29	Show
GSE74704	ADK	132	1	2	17	Show
TCGA	ADK	132	11	25	60	Show

Total number of gains: 33; Total number of losses: 84; Total Number of normals: 371.  Download Data

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Somatic mutations of ADK:

 

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Highly correlated genes for ADK:

 

Showing top 20/729 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
ADK	UBE2L3	0.671648	3	0	3
ADK	DNAJA2	0.664304	8	0	5
ADK	CDK7	0.657938	12	0	10
ADK	CYB5R2	0.652357	4	0	3
ADK	PLA2G4F	0.65135	3	0	3
ADK	COMMD1	0.649883	3	0	3
ADK	ORMDL2	0.647644	11	0	9
ADK	RPS17	0.646549	3	0	3
ADK	EIF3J	0.645367	5	0	4
ADK	UGP2	0.643359	5	0	3
ADK	RTCA	0.643321	10	0	9
ADK	AP3B1	0.641144	10	0	8
ADK	PGAM1	0.638722	11	0	8
ADK	VDAC1	0.635435	12	0	10
ADK	SH3RF2	0.630422	6	0	5
ADK	COMMD8	0.629952	9	0	8
ADK	SEMA4B	0.628713	4	0	4
ADK	PNPLA5	0.625684	3	0	3
ADK	SDR9C7	0.625646	6	0	5
ADK	DUOXA1	0.624134	7	0	6

For details and further investigation, click here